EA200400666A3 - Новые соединения бензотиазина и бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат - Google Patents

Новые соединения бензотиазина и бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат

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Publication number
EA200400666A3
EA200400666A3 EA200400666A EA200400666A EA200400666A3 EA 200400666 A3 EA200400666 A3 EA 200400666A3 EA 200400666 A EA200400666 A EA 200400666A EA 200400666 A EA200400666 A EA 200400666A EA 200400666 A3 EA200400666 A3 EA 200400666A3
Authority
EA
Eurasian Patent Office
Prior art keywords
hydrogen
preparation
pharmaceutical compositions
compositions containing
alkyl
Prior art date
Application number
EA200400666A
Other languages
English (en)
Other versions
EA200400666A2 (ru
EA008797B1 (ru
Inventor
Патрик Десо
Алекс Корди
Пьер Лестаж
Original Assignee
Ле Лаборатуар Сервье
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ле Лаборатуар Сервье filed Critical Ле Лаборатуар Сервье
Publication of EA200400666A2 publication Critical patent/EA200400666A2/ru
Publication of EA200400666A3 publication Critical patent/EA200400666A3/ru
Publication of EA008797B1 publication Critical patent/EA008797B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Соединения формулы (I)где Rпредставляет собой водород, галоген или алкил,Rпредставляет собой водород или алкил,Rпредставляет собой водород, галоген или гидрокси,A представляет собой CRRили NR,Rпредставляет собой водород, алкил или циклоалкил,Rпредставляет собой атом водород или алкил,илиA представляет собой азот и вместе со смежной -CHR- образует кольцогде m представляет собой 1, 2 или 3,Rпредставляет водород или галоген,X имеет значения, указанные в описании,их изомеры, а также их аддитивные соли. Лекарственные средства.
EA200400666A 2003-06-13 2004-06-11 Новые соединения бензотиазина и бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат EA008797B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0307118A FR2856065B1 (fr) 2003-06-13 2003-06-13 Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (3)

Publication Number Publication Date
EA200400666A2 EA200400666A2 (ru) 2004-12-30
EA200400666A3 true EA200400666A3 (ru) 2005-10-27
EA008797B1 EA008797B1 (ru) 2007-08-31

Family

ID=33186482

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200400666A EA008797B1 (ru) 2003-06-13 2004-06-11 Новые соединения бензотиазина и бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат

Country Status (28)

Country Link
US (2) US7253162B2 (ru)
EP (1) EP1486503B1 (ru)
JP (1) JP2005002114A (ru)
KR (1) KR100586683B1 (ru)
CN (1) CN1277823C (ru)
AR (1) AR044672A1 (ru)
AT (1) ATE344265T1 (ru)
AU (1) AU2004202586A1 (ru)
BR (1) BRPI0401956A (ru)
CA (1) CA2470263A1 (ru)
CY (1) CY1105939T1 (ru)
DE (1) DE602004002990T2 (ru)
DK (1) DK1486503T3 (ru)
EA (1) EA008797B1 (ru)
EG (1) EG24207A (ru)
ES (1) ES2276249T3 (ru)
FR (1) FR2856065B1 (ru)
GE (1) GEP20063815B (ru)
HK (1) HK1071750A1 (ru)
HR (1) HRP20070030T3 (ru)
MA (1) MA27092A1 (ru)
MX (1) MXPA04005580A (ru)
NO (1) NO20042422L (ru)
NZ (1) NZ533472A (ru)
PL (1) PL1486503T3 (ru)
PT (1) PT1486503E (ru)
SG (1) SG148023A1 (ru)
SI (1) SI1486503T1 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1943226A2 (en) 2005-10-13 2008-07-16 Smithkline Beecham Corporation Phenol ethers as modulators of the opioid receptors
WO2008030448A1 (en) * 2006-09-07 2008-03-13 Millennium Pharmaceuticals, Inc. Phenethylamide derivatives with kinase inhibitory activity
GB0821166D0 (en) * 2008-11-19 2008-12-24 Glaxo Group Ltd Compounds
FR2955106B1 (fr) * 2010-01-08 2011-12-23 Servier Lab Nouveaux derives de benzothiadiazines cyclopropylees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP6134654B2 (ja) * 2012-02-08 2017-05-24 武田薬品工業株式会社 複素環化合物およびその用途
WO2019130229A1 (en) * 2017-12-28 2019-07-04 Mylan Laboratories Ltd Methods and intermediates for preparing rucaparib

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1377693A (fr) * 1962-12-06 1964-11-06 Geigy Ag J R Nouveaux composés dibenzo [1.2] thiaziniques et produits pesticides qui en contiennent
FR2722502B1 (fr) * 1994-07-12 1996-08-23 Adir Nouveau derive de benzothiadiazine, son procede depreparation et les compositions pharmaceutiques qui le contiennent
ZA991301B (en) * 1998-02-18 1999-09-13 Neurosearch As Glutamate receptor modulators.
FR2823753B1 (fr) * 2001-04-18 2004-07-16 Servier Lab Nouveau procede de synthese de la (3as)-5,5-dioxo-2,3,3a, 4-tetrahydro-1h-pyrrolo [2,1-c] [1,2,4] benzothiadiazine
FR2833956B1 (fr) * 2001-12-21 2004-01-30 Servier Lab Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2833950B1 (fr) * 2001-12-21 2005-12-16 Servier Lab Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
CY1105939T1 (el) 2011-04-06
ATE344265T1 (de) 2006-11-15
SG148023A1 (en) 2008-12-31
EA200400666A2 (ru) 2004-12-30
EP1486503B1 (fr) 2006-11-02
EP1486503A1 (fr) 2004-12-15
US7423034B2 (en) 2008-09-09
EA008797B1 (ru) 2007-08-31
MXPA04005580A (es) 2005-03-23
CN1572791A (zh) 2005-02-02
AU2004202586A1 (en) 2005-01-06
MA27092A1 (fr) 2004-12-20
KR20040107410A (ko) 2004-12-20
US20070249594A1 (en) 2007-10-25
JP2005002114A (ja) 2005-01-06
FR2856065A1 (fr) 2004-12-17
FR2856065B1 (fr) 2005-08-19
CA2470263A1 (fr) 2004-12-13
PT1486503E (pt) 2007-01-31
HK1071750A1 (en) 2005-07-29
DE602004002990D1 (de) 2006-12-14
AR044672A1 (es) 2005-09-21
SI1486503T1 (sl) 2007-02-28
ES2276249T3 (es) 2007-06-16
NZ533472A (en) 2005-09-30
US7253162B2 (en) 2007-08-07
CN1277823C (zh) 2006-10-04
DE602004002990T2 (de) 2007-07-05
KR100586683B1 (ko) 2006-06-08
PL1486503T3 (pl) 2006-12-29
BRPI0401956A (pt) 2005-06-28
DK1486503T3 (da) 2007-02-26
HRP20070030T3 (en) 2007-08-31
US20040254161A1 (en) 2004-12-16
EG24207A (en) 2008-10-21
NO20042422L (no) 2004-12-14
GEP20063815B (en) 2006-05-10

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU