HRP20031013A2 - (PIRIDO/THIENO)-[f]-OXAZEPIN-5-ONE DERIVATIVES - Google Patents

(PIRIDO/THIENO)-[f]-OXAZEPIN-5-ONE DERIVATIVES Download PDF

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Publication number
HRP20031013A2
HRP20031013A2 HR20031013A HRP20031013A HRP20031013A2 HR P20031013 A2 HRP20031013 A2 HR P20031013A2 HR 20031013 A HR20031013 A HR 20031013A HR P20031013 A HRP20031013 A HR P20031013A HR P20031013 A2 HRP20031013 A2 HR P20031013A2
Authority
HR
Croatia
Prior art keywords
alkyl
formula
pyrido
oxazepin
thien
Prior art date
Application number
HR20031013A
Other languages
English (en)
Croatian (hr)
Inventor
James Anthony Grove Simon
Adam-Worrall Julia
Gilfillan Robert
Original Assignee
Akzo Nobel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.
Publication of HRP20031013A2 publication Critical patent/HRP20031013A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HR20031013A 2001-06-14 2002-06-10 (PIRIDO/THIENO)-[f]-OXAZEPIN-5-ONE DERIVATIVES HRP20031013A2 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01202284 2001-06-14
PCT/EP2002/006364 WO2002102808A2 (en) 2001-06-14 2002-06-10 (PYRIDO/THIENO)-[f]-OXAZEPIN-5-ONE DERIVATIVES AS POSITIVE MODULATORS OF THE AMPA RECEPTOR

Publications (1)

Publication Number Publication Date
HRP20031013A2 true HRP20031013A2 (hr) 2005-10-31

Family

ID=8180476

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20031013A HRP20031013A2 (hr) 2001-06-14 2002-06-10 (PIRIDO/THIENO)-[f]-OXAZEPIN-5-ONE DERIVATIVES

Country Status (25)

Country Link
US (3) US7345036B2 (cs)
EP (1) EP1446407A2 (cs)
JP (1) JP4435562B2 (cs)
KR (1) KR100864267B1 (cs)
CN (2) CN101029051B (cs)
AR (1) AR034482A1 (cs)
AU (1) AU2002320841B2 (cs)
BR (1) BR0210307A (cs)
CA (1) CA2449215C (cs)
CO (1) CO5550448A2 (cs)
CZ (1) CZ296217B6 (cs)
EC (1) ECSP034890A (cs)
HR (1) HRP20031013A2 (cs)
HU (1) HUP0400196A3 (cs)
IL (2) IL158928A0 (cs)
IS (1) IS7042A (cs)
MX (1) MXPA03011562A (cs)
NO (1) NO328710B1 (cs)
NZ (1) NZ529671A (cs)
PE (1) PE20030271A1 (cs)
PL (1) PL367185A1 (cs)
RU (1) RU2286347C2 (cs)
SK (1) SK287583B6 (cs)
WO (1) WO2002102808A2 (cs)
ZA (1) ZA200309096B (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200817385A (en) * 2006-07-04 2008-04-16 Organon Nv Heterocyclic derivatives
GB0624879D0 (en) * 2006-12-14 2007-01-24 Shs Int Ltd Treatment of pervasive development disorders
FR2964969B1 (fr) * 2010-09-16 2012-08-24 Servier Lab Nouveaux derives dihydrobenzoxathiazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1238719A (cs) 1968-11-01 1971-07-07
EP1367056A1 (en) 1992-07-24 2003-12-03 The Regents Of The University Of California Drugs that enhance synaptic responses mediated by AMPA receptors
NZ295657A (en) * 1994-11-02 1998-08-26 Janssen Pharmaceutica Nv Tetracyclic oxazepine and thiazepine derivatives, medicaments and intermediate compounds
ATE203026T1 (de) 1995-01-06 2001-07-15 Hoffmann La Roche Hydroxymethyl-imidazodiazepine und deren ester
US5650409A (en) * 1995-06-02 1997-07-22 Cortex Pharmaceuticals, Inc. Benzoyl piperidines/pyrrolidines for enhancing synaptic response
US5736543A (en) * 1996-04-03 1998-04-07 The Regents Of The University Of California Benzoxazines for enhancing synaptic response
EP0884310B1 (en) 1997-06-09 2005-09-07 Pfizer Products Inc. Quinazolin-4-one ampa antagonists
US5985871A (en) 1997-12-24 1999-11-16 Cortex Pharmaceuticals, Inc. Benzoxazine compounds for enhancing synaptic response
AU751384B2 (en) 1998-02-18 2002-08-15 Neurosearch A/S Novel compounds and their use as positive AMPA receptor modulators
US6124278A (en) 1998-04-03 2000-09-26 The Regents Of The University Of California Acylbenzoxazines for enhancing synaptic response
ATE367393T1 (de) 1999-05-12 2007-08-15 Us Health Thiazepin-hemmer von hiv-1 integrase
TWI232863B (en) 2001-06-11 2005-05-21 Akzo Nobel Nv Benzoxazepine derivatives

Also Published As

Publication number Publication date
CA2449215A1 (en) 2002-12-27
BR0210307A (pt) 2004-07-13
SK15262003A3 (sk) 2004-05-04
PL367185A1 (en) 2005-02-21
CN1255413C (zh) 2006-05-10
AR034482A1 (es) 2004-02-25
WO2002102808A2 (en) 2002-12-27
NO328710B1 (no) 2010-05-03
IL158928A (en) 2008-11-26
AU2002320841B2 (en) 2008-02-28
RU2286347C2 (ru) 2006-10-27
EP1446407A2 (en) 2004-08-18
CN1516701A (zh) 2004-07-28
NO20035523D0 (no) 2003-12-11
CO5550448A2 (es) 2005-08-31
JP4435562B2 (ja) 2010-03-17
US7566778B2 (en) 2009-07-28
MXPA03011562A (es) 2004-03-18
ZA200309096B (en) 2005-02-21
US20040220175A1 (en) 2004-11-04
CZ20033392A3 (en) 2004-05-12
US20090163473A1 (en) 2009-06-25
RU2004100702A (ru) 2005-06-10
US8034804B2 (en) 2011-10-11
SK287583B6 (sk) 2011-03-04
PE20030271A1 (es) 2003-03-19
CA2449215C (en) 2011-03-22
JP2005500301A (ja) 2005-01-06
CZ296217B6 (cs) 2006-02-15
WO2002102808A3 (en) 2003-03-20
NZ529671A (en) 2005-10-28
HUP0400196A3 (en) 2007-05-02
IL158928A0 (en) 2004-05-12
US20080262221A1 (en) 2008-10-23
US7345036B2 (en) 2008-03-18
IS7042A (is) 2003-11-17
KR20040007703A (ko) 2004-01-24
KR100864267B1 (ko) 2008-10-20
HUP0400196A2 (hu) 2004-07-28
CN101029051B (zh) 2010-06-09
CN101029051A (zh) 2007-09-05
ECSP034890A (es) 2004-01-28

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AU2002314144A1 (en) Benzoxazepine derivatives and their use as AMPA receptor stimulators
AU2002320841A1 (en) (Pyrido/thieno)-[f]-oxazepin-5-one derivatives as positive modulators of the AMPA receptor
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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
PPPP Transfer of rights

Owner name: N.V. ORGANON, NL

ODRP Renewal fee for the maintenance of a patent

Payment date: 20110526

Year of fee payment: 10

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