HRP20030510A2 - Gel composition and trans-scrotal application of acomposition for the treatment of hypogonadism - Google Patents
Gel composition and trans-scrotal application of acomposition for the treatment of hypogonadism Download PDFInfo
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- HRP20030510A2 HRP20030510A2 HR20030510A HRP20030510A HRP20030510A2 HR P20030510 A2 HRP20030510 A2 HR P20030510A2 HR 20030510 A HR20030510 A HR 20030510A HR P20030510 A HRP20030510 A HR P20030510A HR P20030510 A2 HRP20030510 A2 HR P20030510A2
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- testosterone
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- 239000012188 paraffin wax Substances 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- IPBVNPXQWQGGJP-UHFFFAOYSA-N phenyl acetate Chemical class CC(=O)OC1=CC=CC=C1 IPBVNPXQWQGGJP-UHFFFAOYSA-N 0.000 description 1
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical class OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 description 1
- 210000003635 pituitary gland Anatomy 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 230000037307 sensitive skin Effects 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 231100001068 severe skin irritation Toxicity 0.000 description 1
- 210000004999 sex organ Anatomy 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Pregnancy & Childbirth (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Colloid Chemistry (AREA)
- Cosmetics (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
- Dental Preparations (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10064205 | 2000-12-22 | ||
| PCT/EP2001/015123 WO2002051421A2 (de) | 2000-12-22 | 2001-12-20 | Gelzusammensetzung und transskrotale applikation einer zusammensetzung zur behandlung von hypogonadismus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20030510A2 true HRP20030510A2 (en) | 2005-04-30 |
Family
ID=7668398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20030510A HRP20030510A2 (en) | 2000-12-22 | 2003-06-20 | Gel composition and trans-scrotal application of acomposition for the treatment of hypogonadism |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20040044086A1 (sl) |
| EP (1) | EP1347764B1 (sl) |
| AT (1) | ATE356626T1 (sl) |
| CA (1) | CA2432534C (sl) |
| CY (1) | CY1106595T1 (sl) |
| CZ (1) | CZ20031761A3 (sl) |
| DE (2) | DE50112206D1 (sl) |
| DK (1) | DK1347764T3 (sl) |
| EE (1) | EE05318B1 (sl) |
| ES (1) | ES2283446T3 (sl) |
| HR (1) | HRP20030510A2 (sl) |
| HU (1) | HUP0600234A3 (sl) |
| PL (1) | PL206702B1 (sl) |
| PT (1) | PT1347764E (sl) |
| SI (1) | SI1347764T1 (sl) |
| SK (1) | SK7932003A3 (sl) |
| WO (1) | WO2002051421A2 (sl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| US20040002482A1 (en) * | 2000-08-30 | 2004-01-01 | Dudley Robert E. | Androgen pharmaceutical composition and method for treating depression |
| US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
| MY139721A (en) * | 2002-04-19 | 2009-10-30 | Cpex Pharmaceuticals Inc | Pharmaceutical composition |
| BRPI0515040B1 (pt) * | 2004-09-09 | 2021-10-13 | Besins Healthcare Luxembourg S.A.R.L | Géis de testosterona compreendendo propileno glicol como intensificador de penetração |
| EP1634583A1 (en) * | 2004-09-09 | 2006-03-15 | Laboratoires Besins International | Testosterone gels comprising propylene glycol as penetration enhancer |
| US20070088012A1 (en) * | 2005-04-08 | 2007-04-19 | Woun Seo | Method of treating or preventing type-2 diabetes |
| ZA200803087B (en) | 2005-10-12 | 2009-11-25 | Unimed Pharmaceuticals Llc | Improved testosterone gel and method of use |
| US20130040923A1 (en) | 2011-05-13 | 2013-02-14 | Trimel Pharmaceuticals Corporation | Intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
| US20130045958A1 (en) | 2011-05-13 | 2013-02-21 | Trimel Pharmaceuticals Corporation | Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
| US9757388B2 (en) | 2011-05-13 | 2017-09-12 | Acerus Pharmaceuticals Srl | Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels |
| US11744838B2 (en) | 2013-03-15 | 2023-09-05 | Acerus Biopharma Inc. | Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3860712A (en) * | 1973-04-16 | 1975-01-14 | Sterling Drug Inc | Composition and method for treatment of acne or seborrhea |
| CA1165240A (en) * | 1980-07-09 | 1984-04-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions |
| CA1249968A (en) * | 1984-04-05 | 1989-02-14 | Kazuo Kigasawa | Ointment base |
| US4725439A (en) * | 1984-06-29 | 1988-02-16 | Alza Corporation | Transdermal drug delivery device |
| US5776923A (en) * | 1993-01-19 | 1998-07-07 | Endorecherche, Inc. | Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone |
| DK3994A (da) * | 1994-01-10 | 1995-07-11 | Frank Nielsen | CDopbevaringssystem hvor CDcoverne monteres på en skinne |
| WO1997041865A1 (de) * | 1996-05-02 | 1997-11-13 | Azupharma Gmbh | Topische penile androgen-applikation zur behandlung der erektilen dysfunktion |
| JP2000513336A (ja) * | 1996-05-22 | 2000-10-10 | ディバーシファイド ファーマシューティカルズ，インコーポレーテッド | 薬物の経皮送達のための組成物、方法及びデバイス |
| US5968919A (en) * | 1997-10-16 | 1999-10-19 | Macrochem Corporation | Hormone replacement therapy drug formulations for topical application to the skin |
| DE69840426D1 (de) * | 1997-11-10 | 2009-02-12 | Strakan Int Ltd | Penetrationsfördernde und irritationsvermindernde Systeme mit Testosteron |
| DE19803193C1 (de) * | 1998-01-28 | 1999-07-15 | August Wolff Gmbh & Co Arzneim | Pharmazeutische Zusammensetzung mit Lecithin und alpha-Bisabolol als Penetrationsbeschleuniger |
| ATE485837T1 (de) * | 2000-08-03 | 2010-11-15 | Antares Pharma Ipl Ag | Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert |
| US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| US20040072810A1 (en) * | 2001-11-07 | 2004-04-15 | Besins International Belgique | Pharmaceutical composition in the form of a gel or a solution based on dihydrotestosterone, process for preparing it and uses thereof |
| DK1317921T3 (da) * | 2001-12-07 | 2009-12-21 | Besins Mfg Belgium | Farmaceutisk sammensætning i form af en gel eller oplösning med dihydrotestosteron, fremgangsmåde til fremstilling og anvendelser heraf |
-
2001
- 2001-12-20 SK SK793-2003A patent/SK7932003A3/sk unknown
- 2001-12-20 WO PCT/EP2001/015123 patent/WO2002051421A2/de active IP Right Grant
- 2001-12-20 CA CA002432534A patent/CA2432534C/en not_active Expired - Fee Related
- 2001-12-20 EE EEP200300305A patent/EE05318B1/xx not_active IP Right Cessation
- 2001-12-20 PT PT01985426T patent/PT1347764E/pt unknown
- 2001-12-20 PL PL366101A patent/PL206702B1/pl not_active IP Right Cessation
- 2001-12-20 DK DK01985426T patent/DK1347764T3/da active
- 2001-12-20 CZ CZ20031761A patent/CZ20031761A3/cs unknown
- 2001-12-20 AT AT01985426T patent/ATE356626T1/de not_active IP Right Cessation
- 2001-12-20 ES ES01985426T patent/ES2283446T3/es not_active Expired - Lifetime
- 2001-12-20 SI SI200130714T patent/SI1347764T1/sl unknown
- 2001-12-20 DE DE50112206T patent/DE50112206D1/de not_active Expired - Lifetime
- 2001-12-20 US US10/451,482 patent/US20040044086A1/en not_active Abandoned
- 2001-12-20 HU HU0600234A patent/HUP0600234A3/hu unknown
- 2001-12-20 EP EP01985426A patent/EP1347764B1/de not_active Expired - Lifetime
- 2001-12-20 DE DE20121209U patent/DE20121209U1/de not_active Expired - Lifetime
-
2003
- 2003-06-20 HR HR20030510A patent/HRP20030510A2/hr not_active Application Discontinuation
-
2007
- 2007-05-16 CY CY20071100660T patent/CY1106595T1/el unknown
-
2010
- 2010-06-07 US US12/795,348 patent/US20100317631A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| SI1347764T1 (sl) | 2007-06-30 |
| CZ20031761A3 (cs) | 2004-01-14 |
| HUP0600234A2 (en) | 2006-07-28 |
| DE50112206D1 (de) | 2007-04-26 |
| HUP0600234A3 (en) | 2011-04-28 |
| US20040044086A1 (en) | 2004-03-04 |
| PT1347764E (pt) | 2007-06-01 |
| EE200300305A (et) | 2003-12-15 |
| SK7932003A3 (en) | 2003-11-04 |
| CA2432534C (en) | 2009-09-22 |
| EP1347764B1 (de) | 2007-03-14 |
| ATE356626T1 (de) | 2007-04-15 |
| EP1347764A2 (de) | 2003-10-01 |
| EE05318B1 (et) | 2010-08-16 |
| DK1347764T3 (da) | 2007-07-23 |
| WO2002051421A2 (de) | 2002-07-04 |
| PL366101A1 (en) | 2005-01-24 |
| US20100317631A1 (en) | 2010-12-16 |
| DE20121209U1 (de) | 2002-06-20 |
| WO2002051421A3 (de) | 2002-11-07 |
| CA2432534A1 (en) | 2002-07-04 |
| PL206702B1 (pl) | 2010-09-30 |
| ES2283446T3 (es) | 2007-11-01 |
| CY1106595T1 (el) | 2012-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| ODBI | Application refused |