HN1998000143A - Tetrahidronaftalenos substituidos y compuestos analogos. - Google Patents
Tetrahidronaftalenos substituidos y compuestos analogos.Info
- Publication number
- HN1998000143A HN1998000143A HN1998000143A HN1998000143A HN1998000143A HN 1998000143 A HN1998000143 A HN 1998000143A HN 1998000143 A HN1998000143 A HN 1998000143A HN 1998000143 A HN1998000143 A HN 1998000143A HN 1998000143 A HN1998000143 A HN 1998000143A
- Authority
- HN
- Honduras
- Prior art keywords
- substituted
- tetrahidronaftalenos
- hetero
- tetrahydroquinolines
- analog compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19741051A DE19741051A1 (de) | 1997-09-18 | 1997-09-18 | Hetero-Tetrahydrochinoline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HN1998000143A true HN1998000143A (es) | 1999-04-09 |
Family
ID=7842737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HN1998000143A HN1998000143A (es) | 1997-09-18 | 1998-09-18 | Tetrahidronaftalenos substituidos y compuestos analogos. |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US6387929B1 (enExample) |
| EP (1) | EP1017692B1 (enExample) |
| JP (1) | JP2001516757A (enExample) |
| AT (1) | ATE260910T1 (enExample) |
| AU (1) | AU9536898A (enExample) |
| DE (2) | DE19741051A1 (enExample) |
| DK (1) | DK1017692T3 (enExample) |
| ES (1) | ES2216316T3 (enExample) |
| HN (1) | HN1998000143A (enExample) |
| PT (1) | PT1017692E (enExample) |
| WO (1) | WO1999014215A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6642268B2 (en) | 1994-09-13 | 2003-11-04 | G.D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors |
| DE19741051A1 (de) * | 1997-09-18 | 1999-03-25 | Bayer Ag | Hetero-Tetrahydrochinoline |
| EP1340508A1 (en) | 1998-12-23 | 2003-09-03 | G.D. Searle LLC. | Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications |
| US7115279B2 (en) | 2000-08-03 | 2006-10-03 | Curatolo William J | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors |
| EP1269994A3 (en) | 2001-06-22 | 2003-02-12 | Pfizer Products Inc. | Pharmaceutical compositions comprising drug and concentration-enhancing polymers |
| CA2448825C (en) | 2001-06-22 | 2009-08-11 | Pfizer Products Inc. | Pharmaceutical compositions of adsorbates of amorphous drug |
| ES2333645T3 (es) | 2001-06-22 | 2010-02-25 | Bend Research, Inc. | Composiciones farmaceuticas de dispersiones de medicamentos y polimeros neutros. |
| DE10148436A1 (de) * | 2001-10-01 | 2003-04-17 | Bayer Ag | Tetrahydrochinoline |
| ATE509326T1 (de) | 2001-12-18 | 2011-05-15 | L 1 Secure Credentialing Inc | Mehrfachbildsicherheitsmerkmale zur identifikation von dokumenten und verfahren zu ihrer herstellung |
| BR0215240A (pt) | 2001-12-19 | 2004-10-26 | Atherogenics Inc | Derivados de calcona e seu uso no tratamento de doenças |
| AU2002361811A1 (en) | 2001-12-19 | 2003-07-09 | Atherogenics, Inc. | 1,3-bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders |
| US7728048B2 (en) | 2002-12-20 | 2010-06-01 | L-1 Secure Credentialing, Inc. | Increasing thermal conductivity of host polymer used with laser engraving methods and compositions |
| CA2471639A1 (en) | 2002-01-17 | 2003-07-31 | Pharmacia Corporation | Novel alkyl/aryl hydroxy or keto thiepines. |
| AR038375A1 (es) | 2002-02-01 | 2005-01-12 | Pfizer Prod Inc | Composiciones farmaceuticas de inhibidores de la proteina de transferencia de esteres de colesterilo |
| ES2305434T3 (es) | 2002-02-01 | 2008-11-01 | Pfizer Products Inc. | Composiciones framaceuticas de dispersiones amorfas de farmacos y materiales que forman microfases lipofilas. |
| US7824029B2 (en) | 2002-05-10 | 2010-11-02 | L-1 Secure Credentialing, Inc. | Identification card printer-assembler for over the counter card issuing |
| ATE407670T1 (de) | 2002-12-20 | 2008-09-15 | Pfizer Prod Inc | Dosierungsform enthaltend einen cetp-hemmer und einen hmg-coa reduktase hemmer |
| JP5546715B2 (ja) | 2003-03-17 | 2014-07-09 | 日本たばこ産業株式会社 | Ｃｅｔｐ阻害剤の医薬組成物 |
| DE602004030434D1 (de) | 2003-04-16 | 2011-01-20 | L 1 Secure Credentialing Inc | Dreidimensionale datenspeicherung |
| TWI494102B (zh) * | 2003-05-02 | 2015-08-01 | Japan Tobacco Inc | 包含ｓ-〔２（〔〔１-（２-乙基丁基）環己基〕羰基〕胺基）苯基〕２-甲基丙烷硫酯及ｈｍｇ輔酶ａ還原酶抑制劑之組合 |
| BRPI0413277A (pt) | 2003-08-04 | 2006-10-10 | Pfizer Prod Inc | composições farmacêuticas de adsorvatos de medicamentos amorfos e materiais que formam microfases lipofìlicas |
| CL2004001884A1 (es) | 2003-08-04 | 2005-06-03 | Pfizer Prod Inc | Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros. |
| KR20060080214A (ko) * | 2003-09-26 | 2006-07-07 | 니뽄 다바코 산교 가부시키가이샤 | 잔여 리포프로테인 생산 저해 방법 |
| CN1946734B (zh) * | 2004-02-26 | 2012-07-18 | 贝勒研究院 | 系统性治疗关节炎的组合物和方法 |
| US8127137B2 (en) | 2004-03-18 | 2012-02-28 | Digimarc Corporation | Watermark payload encryption for media including multiple watermarks |
| WO2006047537A1 (en) * | 2004-10-25 | 2006-05-04 | Cytokinetics, Inc. | Certain compounds, compositions, and methods |
| WO2006065842A2 (en) * | 2004-12-13 | 2006-06-22 | Synta Pharmaceuticals Corp. | 5,6,7,8-tetrahydroquinolines and related compounds and uses thereof |
| DK1828137T3 (da) | 2004-12-18 | 2012-07-23 | Bayer Pharma AG | 4-Cycloalkyl-substituerede tetrahydroquinolinderivater og deres anvendelse som medikamenter |
| WO2006072362A1 (de) * | 2004-12-18 | 2006-07-13 | Bayer Healthcare Ag | (5s) - 3 - [(s)-fluor (4-trifluoromethylphenyl) methyl] -5,6,7,8-tetrahydrochinolin-5-ol derivative und ihre verwendung als cetp-inhibitoren |
| WO2006082518A1 (en) | 2005-02-03 | 2006-08-10 | Pfizer Products Inc. | Pharmaceutical compositions with enhanced performance |
| WO2006098394A1 (ja) * | 2005-03-14 | 2006-09-21 | Japan Tobacco Inc. | 脂質吸収抑制方法および脂質吸収抑制剤 |
| US7737155B2 (en) | 2005-05-17 | 2010-06-15 | Schering Corporation | Nitrogen-containing heterocyclic compounds and methods of use thereof |
| KR20080059233A (ko) | 2005-10-21 | 2008-06-26 | 노파르티스 아게 | 레닌 억제제, 및 항이상지질혈증제 및/또는 항비만제의조합물 |
| DE102006012548A1 (de) * | 2006-03-18 | 2007-09-20 | Bayer Healthcare Ag | Substituierte Chromanol-Derivate und ihre Verwendung |
| NZ587748A (en) * | 2008-03-05 | 2012-01-12 | Boehringer Ingelheim Int | Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation |
| EP2379547A1 (en) | 2008-12-16 | 2011-10-26 | Schering Corporation | Pyridopyrimidine derivatives and methods of use thereof |
| WO2010075069A1 (en) | 2008-12-16 | 2010-07-01 | Schering Corporation | Bicyclic pyranone derivatives as nicotinic acid receptor agonists |
| JP5780528B2 (ja) | 2010-02-19 | 2015-09-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 三環式ピリジン誘導体、このような化合物を含有する医薬、それらの使用、およびそれらの調製方法 |
| NZ606100A (en) * | 2010-07-09 | 2014-08-29 | Daiichi Sankyo Co Ltd | Substituted pyridine compound |
| US20130156720A1 (en) | 2010-08-27 | 2013-06-20 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
| EP2760868B1 (en) | 2011-08-17 | 2018-04-25 | Boehringer Ingelheim International GmbH | Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation |
| EP2801574B1 (en) * | 2012-01-06 | 2016-07-27 | Daiichi Sankyo Company, Limited | Acid adduct salts of substituted pyridine compound as cholesteryl ester transfer protein (cetp) inhibitors |
| US20230227410A1 (en) * | 2022-01-17 | 2023-07-20 | King Abdulaziz University | Tetrahydroquinoline derivatives and a process of preparation thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5169857A (en) | 1988-01-20 | 1992-12-08 | Bayer Aktiengesellschaft | 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis |
| CA1336714C (en) * | 1987-08-20 | 1995-08-15 | Yoshihiro Fujikawa | Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis |
| DE68918713T2 (de) | 1988-01-18 | 1995-03-16 | Toshiba Kawasaki Kk | Interne Pumpe für Kernreaktor. |
| NO177005C (no) * | 1988-01-20 | 1995-07-05 | Bayer Ag | Analogifremgangsmåte for fremstilling av substituerte pyridiner, samt mellomprodukter til bruk ved fremstillingen |
| DE19627431A1 (de) * | 1996-07-08 | 1998-01-15 | Bayer Ag | Heterocyclisch kondensierte Pyridine |
| DE19709125A1 (de) * | 1997-03-06 | 1998-09-10 | Bayer Ag | Substituierte Chinoline |
| DE19741051A1 (de) * | 1997-09-18 | 1999-03-25 | Bayer Ag | Hetero-Tetrahydrochinoline |
-
1997
- 1997-09-18 DE DE19741051A patent/DE19741051A1/de not_active Withdrawn
-
1998
- 1998-09-07 AT AT98948919T patent/ATE260910T1/de not_active IP Right Cessation
- 1998-09-07 AU AU95368/98A patent/AU9536898A/en not_active Abandoned
- 1998-09-07 ES ES98948919T patent/ES2216316T3/es not_active Expired - Lifetime
- 1998-09-07 EP EP98948919A patent/EP1017692B1/de not_active Expired - Lifetime
- 1998-09-07 US US09/508,399 patent/US6387929B1/en not_active Expired - Fee Related
- 1998-09-07 PT PT98948919T patent/PT1017692E/pt unknown
- 1998-09-07 DK DK98948919T patent/DK1017692T3/da active
- 1998-09-07 DE DE59810922T patent/DE59810922D1/de not_active Expired - Fee Related
- 1998-09-07 JP JP2000511764A patent/JP2001516757A/ja active Pending
- 1998-09-07 WO PCT/EP1998/005656 patent/WO1999014215A1/de not_active Ceased
- 1998-09-18 HN HN1998000143A patent/HN1998000143A/es unknown
-
2001
- 2001-10-31 US US09/999,233 patent/US6958346B2/en not_active Expired - Fee Related
-
2005
- 2005-10-25 US US11/257,931 patent/US7192971B2/en not_active Expired - Fee Related
-
2007
- 2007-02-22 US US11/677,790 patent/US20070142420A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT1017692E (pt) | 2004-06-30 |
| AU9536898A (en) | 1999-04-05 |
| US6387929B1 (en) | 2002-05-14 |
| US20020062024A1 (en) | 2002-05-23 |
| EP1017692A1 (de) | 2000-07-12 |
| DE59810922D1 (de) | 2004-04-08 |
| DE19741051A1 (de) | 1999-03-25 |
| JP2001516757A (ja) | 2001-10-02 |
| US6958346B2 (en) | 2005-10-25 |
| ATE260910T1 (de) | 2004-03-15 |
| WO1999014215A1 (de) | 1999-03-25 |
| ES2216316T3 (es) | 2004-10-16 |
| US20070142420A1 (en) | 2007-06-21 |
| US20060069112A1 (en) | 2006-03-30 |
| EP1017692B1 (de) | 2004-03-03 |
| US7192971B2 (en) | 2007-03-20 |
| DK1017692T3 (da) | 2004-07-12 |
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