HK85987A - Plasminogen activators useful as therapeutic and diagnostic agents and their isolation - Google Patents

Plasminogen activators useful as therapeutic and diagnostic agents and their isolation

Info

Publication number
HK85987A
HK85987A HK859/87A HK85987A HK85987A HK 85987 A HK85987 A HK 85987A HK 859/87 A HK859/87 A HK 859/87A HK 85987 A HK85987 A HK 85987A HK 85987 A HK85987 A HK 85987A
Authority
HK
Hong Kong
Prior art keywords
fibrin
matrix
plasminogen activator
urokinase
affinity
Prior art date
Application number
HK859/87A
Other languages
German (de)
English (en)
French (fr)
Inventor
Syed Shaukat Husain
Boguslaw Lipinski
Victor Gurewich
Original Assignee
Vascular Laboratory Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22237919&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK85987(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vascular Laboratory Inc filed Critical Vascular Laboratory Inc
Publication of HK85987A publication Critical patent/HK85987A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK859/87A 1979-11-13 1987-11-19 Plasminogen activators useful as therapeutic and diagnostic agents and their isolation HK85987A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9324679A 1979-11-13 1979-11-13
PCT/US1980/001450 WO1981001417A1 (en) 1979-11-13 1980-10-29 Isolation of plasminogen activators useful as therapeutic and diagnostic agents

Publications (1)

Publication Number Publication Date
HK85987A true HK85987A (en) 1987-11-27

Family

ID=22237919

Family Applications (1)

Application Number Title Priority Date Filing Date
HK859/87A HK85987A (en) 1979-11-13 1987-11-19 Plasminogen activators useful as therapeutic and diagnostic agents and their isolation

Country Status (11)

Country Link
EP (1) EP0040238B1 (cs)
JP (2) JPH0734743B2 (cs)
AU (1) AU6642281A (cs)
CA (1) CA1164341A (cs)
CY (1) CY1382A (cs)
DE (1) DE3068549D1 (cs)
HK (1) HK85987A (cs)
IT (1) IT1147788B (cs)
MY (1) MY8700685A (cs)
SG (1) SG40587G (cs)
WO (1) WO1981001417A1 (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3068549D1 (en) * 1979-11-13 1984-08-16 Syed Shaukat Husain Plasminogen activators useful as therapeutic and diagnostic agents and their isolation
FI88932C (fi) * 1982-04-15 1993-07-26 Genentech Inc Framstaellning av funktionellt maenskligt urokinasprotein
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
DE3486023T2 (de) * 1983-09-13 1993-06-24 Green Cross Corp Verfahren zur herstellung von urokinase zymogen.
JPS60158115A (ja) * 1984-01-30 1985-08-19 Meiji Milk Prod Co Ltd プラズミノーゲンアクチベーターの製造法
DE3584902D1 (de) * 1984-02-29 1992-01-30 Asahi Chemical Ind Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren.
GB8613221D0 (en) * 1986-05-30 1986-07-02 Bp Chem Int Ltd Recovery process
WO1988008878A1 (en) * 1987-05-15 1988-11-17 Integrated Genetics, Inc. Substances for detecting bloodclots
EP0307774A3 (en) * 1987-09-16 1990-02-28 W.R. Grace & Co.-Conn. Process for purifying plasminogen activator

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL96631C (cs) * 1955-07-01
US2961382A (en) * 1957-07-25 1960-11-22 Ortho Pharma Corp Urokinase-a plasmiogen activator and methods of obtaining the same
US2989440A (en) * 1959-01-23 1961-06-20 Ortho Pharmacentical Corp Urokinase-alpha plasminogen activator and methods of obtaining the same
US3042667A (en) * 1959-03-10 1962-07-03 Pharmacia Ab Process for producing dextran derivatives and products resulting therefrom
US3140984A (en) * 1961-11-30 1964-07-14 Univ Alberta Production of high activity fibrinolytic agents
US3256158A (en) * 1963-03-22 1966-06-14 Abbott Lab Purification of urokinase
US3355361A (en) * 1964-10-15 1967-11-28 Sterling Drug Inc Recovery and purification of urokinase
JPS4810232B1 (cs) * 1970-09-04 1973-04-02
US3755083A (en) * 1971-08-30 1973-08-28 Rand Labor Inc Method for recovering urokinase from urine containing the same
GB1417003A (en) * 1972-06-22 1975-12-10 Radiochemical Centre Ltd Stabilisation of fibrinogen
DE2239791A1 (de) * 1972-08-12 1974-02-21 Hoechst Ag Verfahren zur herstellung von mit indium-113m markiertem humantransferrin
US3812245A (en) * 1972-08-21 1974-05-21 Research Corp Novel compositions for radiotracer localization of deep vein thrombi
US3957582A (en) * 1974-11-20 1976-05-18 Abbott Laboratories Purification of urokinase
FR2347048A2 (fr) * 1976-04-07 1977-11-04 Choay Sa Compositions constituees par des composes du type plasminogene, notamment d'origine placentaire, procede d'obtention des ces compositions, et medicaments contenant ces compositions
JPS51123885A (en) * 1975-04-18 1976-10-28 Hitachi Chem Co Ltd Process for purifying urokinase
US4036945A (en) * 1976-05-03 1977-07-19 The Massachusetts General Hospital Composition and method for determining the size and location of myocardial infarcts
US4094965A (en) * 1977-04-01 1978-06-13 New England Nuclear Corporation Diagnostic agents containing albumin and method for making same
DE2812609A1 (de) * 1977-04-09 1978-10-19 Tanabe Seiyaku Co Verfahren zur reinigung roher urokinase
FR2387242A1 (fr) * 1977-04-12 1978-11-10 Choay Sa Compositions purifiees d'urokinase et procede pour leur obtention
LU80716A1 (fr) * 1978-12-22 1979-05-16 Green Cross Corp Procede pour la production d'une preparation thrombolytique
DE3068549D1 (en) * 1979-11-13 1984-08-16 Syed Shaukat Husain Plasminogen activators useful as therapeutic and diagnostic agents and their isolation
JPH0736755B2 (ja) * 1983-09-13 1995-04-26 株式会社ミドリ十字 プラスミノーゲン・アクチベーター前駆体含有組成物

Also Published As

Publication number Publication date
MY8700685A (en) 1987-12-31
JPS6296085A (ja) 1987-05-02
WO1981001417A1 (en) 1981-05-28
CA1164341A (en) 1984-03-27
IT1147788B (it) 1986-11-26
IT8068733A0 (it) 1980-11-12
EP0040238A1 (en) 1981-11-25
AU6642281A (en) 1981-06-03
CY1382A (en) 1987-12-18
JPS56501474A (cs) 1981-10-15
EP0040238B1 (en) 1984-07-11
SG40587G (en) 1987-07-24
EP0040238A4 (en) 1982-07-13
DE3068549D1 (en) 1984-08-16
JPH0734743B2 (ja) 1995-04-19

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