IT1147788B - Procedimento per la preparazione di attivatori di plasminogeni utili come agenti terapeutici e diagnostici - Google Patents
Procedimento per la preparazione di attivatori di plasminogeni utili come agenti terapeutici e diagnosticiInfo
- Publication number
- IT1147788B IT1147788B IT68733/80A IT6873380A IT1147788B IT 1147788 B IT1147788 B IT 1147788B IT 68733/80 A IT68733/80 A IT 68733/80A IT 6873380 A IT6873380 A IT 6873380A IT 1147788 B IT1147788 B IT 1147788B
- Authority
- IT
- Italy
- Prior art keywords
- therapeutic
- procedure
- preparation
- diagnostic agents
- plasminogen activators
- Prior art date
Links
- 102000001938 Plasminogen Activators Human genes 0.000 title 1
- 108010001014 Plasminogen Activators Proteins 0.000 title 1
- 239000000032 diagnostic agent Substances 0.000 title 1
- 229940039227 diagnostic agent Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940127126 plasminogen activator Drugs 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9324679A | 1979-11-13 | 1979-11-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8068733A0 IT8068733A0 (it) | 1980-11-12 |
| IT1147788B true IT1147788B (it) | 1986-11-26 |
Family
ID=22237919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT68733/80A IT1147788B (it) | 1979-11-13 | 1980-11-12 | Procedimento per la preparazione di attivatori di plasminogeni utili come agenti terapeutici e diagnostici |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0040238B1 (it) |
| JP (2) | JPH0734743B2 (it) |
| AU (1) | AU6642281A (it) |
| CA (1) | CA1164341A (it) |
| CY (1) | CY1382A (it) |
| DE (1) | DE3068549D1 (it) |
| HK (1) | HK85987A (it) |
| IT (1) | IT1147788B (it) |
| MY (1) | MY8700685A (it) |
| SG (1) | SG40587G (it) |
| WO (1) | WO1981001417A1 (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0040238B1 (en) * | 1979-11-13 | 1984-07-11 | HUSAIN, Syed Shaukat | Plasminogen activators useful as therapeutic and diagnostic agents and their isolation |
| IL68366A (en) * | 1982-04-15 | 1990-08-31 | Genentech Inc | Process for expressing a gene encoding a protein comprising the enzymatic portion of human urokinase in a microorganism or cell culture |
| JPS5951220A (ja) * | 1982-08-02 | 1984-03-24 | Asahi Chem Ind Co Ltd | 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤 |
| DE3486023T2 (de) * | 1983-09-13 | 1993-06-24 | Green Cross Corp | Verfahren zur herstellung von urokinase zymogen. |
| JPS60158115A (ja) * | 1984-01-30 | 1985-08-19 | Meiji Milk Prod Co Ltd | プラズミノーゲンアクチベーターの製造法 |
| DE3584902D1 (de) * | 1984-02-29 | 1992-01-30 | Asahi Chemical Ind | Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren. |
| GB8613221D0 (en) * | 1986-05-30 | 1986-07-02 | Bp Chem Int Ltd | Recovery process |
| WO1988008878A1 (en) * | 1987-05-15 | 1988-11-17 | Integrated Genetics, Inc. | Substances for detecting bloodclots |
| EP0307774A3 (en) * | 1987-09-16 | 1990-02-28 | W.R. Grace & Co.-Conn. | Process for purifying plasminogen activator |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE549167A (it) * | 1955-07-01 | |||
| US2961382A (en) * | 1957-07-25 | 1960-11-22 | Ortho Pharma Corp | Urokinase-a plasmiogen activator and methods of obtaining the same |
| US2989440A (en) * | 1959-01-23 | 1961-06-20 | Ortho Pharmacentical Corp | Urokinase-alpha plasminogen activator and methods of obtaining the same |
| US3042667A (en) * | 1959-03-10 | 1962-07-03 | Pharmacia Ab | Process for producing dextran derivatives and products resulting therefrom |
| US3140984A (en) * | 1961-11-30 | 1964-07-14 | Univ Alberta | Production of high activity fibrinolytic agents |
| US3256158A (en) * | 1963-03-22 | 1966-06-14 | Abbott Lab | Purification of urokinase |
| US3355361A (en) * | 1964-10-15 | 1967-11-28 | Sterling Drug Inc | Recovery and purification of urokinase |
| JPS4810232B1 (it) * | 1970-09-04 | 1973-04-02 | ||
| US3755083A (en) * | 1971-08-30 | 1973-08-28 | Rand Labor Inc | Method for recovering urokinase from urine containing the same |
| GB1417003A (en) * | 1972-06-22 | 1975-12-10 | Radiochemical Centre Ltd | Stabilisation of fibrinogen |
| DE2239791A1 (de) * | 1972-08-12 | 1974-02-21 | Hoechst Ag | Verfahren zur herstellung von mit indium-113m markiertem humantransferrin |
| US3812245A (en) * | 1972-08-21 | 1974-05-21 | Research Corp | Novel compositions for radiotracer localization of deep vein thrombi |
| US3957582A (en) * | 1974-11-20 | 1976-05-18 | Abbott Laboratories | Purification of urokinase |
| FR2347048A2 (fr) * | 1976-04-07 | 1977-11-04 | Choay Sa | Compositions constituees par des composes du type plasminogene, notamment d'origine placentaire, procede d'obtention des ces compositions, et medicaments contenant ces compositions |
| JPS51123885A (en) * | 1975-04-18 | 1976-10-28 | Hitachi Chem Co Ltd | Process for purifying urokinase |
| US4036945A (en) * | 1976-05-03 | 1977-07-19 | The Massachusetts General Hospital | Composition and method for determining the size and location of myocardial infarcts |
| US4094965A (en) * | 1977-04-01 | 1978-06-13 | New England Nuclear Corporation | Diagnostic agents containing albumin and method for making same |
| DE2812609A1 (de) * | 1977-04-09 | 1978-10-19 | Tanabe Seiyaku Co | Verfahren zur reinigung roher urokinase |
| FR2387242A1 (fr) * | 1977-04-12 | 1978-11-10 | Choay Sa | Compositions purifiees d'urokinase et procede pour leur obtention |
| LU80716A1 (fr) * | 1978-12-22 | 1979-05-16 | Green Cross Corp | Procede pour la production d'une preparation thrombolytique |
| EP0040238B1 (en) * | 1979-11-13 | 1984-07-11 | HUSAIN, Syed Shaukat | Plasminogen activators useful as therapeutic and diagnostic agents and their isolation |
| JPH0736755B2 (ja) * | 1983-09-13 | 1995-04-26 | 株式会社ミドリ十字 | プラスミノーゲン・アクチベーター前駆体含有組成物 |
-
1980
- 1980-10-29 EP EP80902378A patent/EP0040238B1/en not_active Expired
- 1980-10-29 AU AU66422/81A patent/AU6642281A/en not_active Abandoned
- 1980-10-29 JP JP56500150A patent/JPH0734743B2/ja not_active Expired - Lifetime
- 1980-10-29 CY CY138280A patent/CY1382A/xx unknown
- 1980-10-29 DE DE8080902378T patent/DE3068549D1/de not_active Expired
- 1980-10-29 WO PCT/US1980/001450 patent/WO1981001417A1/en active IP Right Grant
- 1980-11-12 CA CA000364452A patent/CA1164341A/en not_active Expired
- 1980-11-12 IT IT68733/80A patent/IT1147788B/it active
-
1986
- 1986-07-23 JP JP61171970A patent/JPS6296085A/ja active Pending
-
1987
- 1987-05-05 SG SG405/87A patent/SG40587G/en unknown
- 1987-11-19 HK HK859/87A patent/HK85987A/xx not_active IP Right Cessation
- 1987-12-30 MY MY685/87A patent/MY8700685A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6296085A (ja) | 1987-05-02 |
| EP0040238A4 (en) | 1982-07-13 |
| AU6642281A (en) | 1981-06-03 |
| HK85987A (en) | 1987-11-27 |
| JPS56501474A (it) | 1981-10-15 |
| DE3068549D1 (en) | 1984-08-16 |
| EP0040238B1 (en) | 1984-07-11 |
| WO1981001417A1 (en) | 1981-05-28 |
| CA1164341A (en) | 1984-03-27 |
| JPH0734743B2 (ja) | 1995-04-19 |
| EP0040238A1 (en) | 1981-11-25 |
| SG40587G (en) | 1987-07-24 |
| IT8068733A0 (it) | 1980-11-12 |
| CY1382A (en) | 1987-12-18 |
| MY8700685A (en) | 1987-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971125 |