HK186696A - Substituted imidazobenzaze-pines and imidazopyridoaze-pines - Google Patents
Substituted imidazobenzaze-pines and imidazopyridoaze-pinesInfo
- Publication number
- HK186696A HK186696A HK186696A HK186696A HK186696A HK 186696 A HK186696 A HK 186696A HK 186696 A HK186696 A HK 186696A HK 186696 A HK186696 A HK 186696A HK 186696 A HK186696 A HK 186696A
- Authority
- HK
- Hong Kong
- Prior art keywords
- alkyl
- substituted
- aryl
- arylmethyl
- cycloalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59533190A | 1990-10-10 | 1990-10-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK186696A true HK186696A (en) | 1996-10-11 |
Family
ID=24382815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK186696A HK186696A (en) | 1990-10-10 | 1996-10-03 | Substituted imidazobenzaze-pines and imidazopyridoaze-pines |
Country Status (9)
Country | Link |
---|---|
US (1) | US5393753A (fr) |
EP (1) | EP0552292B1 (fr) |
JP (1) | JPH089616B2 (fr) |
AT (1) | ATE124045T1 (fr) |
AU (1) | AU8902591A (fr) |
CA (1) | CA2093797C (fr) |
DE (1) | DE69110685T2 (fr) |
HK (1) | HK186696A (fr) |
WO (1) | WO1992006981A1 (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL101850A (en) * | 1991-06-13 | 1996-01-31 | Janssen Pharmaceutica Nv | History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them |
GR1001385B (el) * | 1992-10-12 | 1993-10-29 | Janssen Pharmaceutica Nv | Παράγωγα ιμιδαζο 1,2-α (πυρρολο,?ειενο η φουρανο) 3,2-d αζεπίνης συν?έσεις και μέ?οδοι χρήσεως. |
GR1001393B (el) * | 1992-10-12 | 1993-10-29 | Janssen Pharmaceutica Nv | Παράγωγα ιμιδαζο[2,1-Β] 3] βενζαζεπίνης, συν?έσεις και μέ?οδος χρήσεως. |
NZ258551A (en) * | 1992-12-04 | 1996-06-25 | Janssen Pharmaceutica Nv | Triazolobenzazepine compounds; includes a process for preparing the compounds and pharmaceutical compositions containing such a compound |
KR100251295B1 (ko) * | 1992-12-04 | 2000-05-01 | 디르크 반테 | 항앨러지성 이미다조[1,2-a](피롤로, 티에노 또는 푸라노)[2,3-d]아제핀 유도체(Antiallergic imidazo[1,2-a](pyrrolo, thieno or furano)[2,3-d]azepine derivatives) |
ATE194350T1 (de) * | 1992-12-04 | 2000-07-15 | Janssen Pharmaceutica Nv | Antiallergisch triazolo (pyrrolo, thieno oder furano) azepinderivate |
ATE198480T1 (de) * | 1993-07-13 | 2001-01-15 | Janssen Pharmaceutica Nv | Antiallergische imidazoazepine |
US5700806A (en) * | 1995-03-24 | 1997-12-23 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
TW382017B (en) * | 1995-12-27 | 2000-02-11 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives |
TW527186B (en) * | 1996-03-19 | 2003-04-11 | Janssen Pharmaceutica Nv | Fused imidazole derivatives as multidrug resistance modulators |
CA2355939C (fr) * | 1998-12-19 | 2010-12-14 | Janssen Pharmaceutica N.V. | Composes spiro antihistaminiques |
US7476662B2 (en) | 2001-06-12 | 2009-01-13 | Janssen Pharmaceutica N.V. | Substituted tetracyclic imidazole derivatives, processes for their preparation, pharmaceutical compositions comprising them and their use as a medicine |
US20050272936A1 (en) * | 2002-06-03 | 2005-12-08 | Axten Jeffrey M | Imidazolium cxcr3 inhibitors |
CA2648115C (fr) * | 2006-03-31 | 2015-03-24 | Vistakon Pharmaceuticals, Llc | Traitements de l'allergie oculaire |
WO2014083571A1 (fr) | 2012-11-29 | 2014-06-05 | Neuland Laboratories Limited | Procédé de préparation d'alcaftadine |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL137020C (fr) * | 1962-08-31 | |||
US3491103A (en) * | 1963-12-19 | 1970-01-20 | Sandoz Ag | Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes |
FR1447527A (fr) * | 1964-08-11 | 1966-07-29 | Sandoz Sa | Nouveaux benzo-cyclohepta-thiophènes et leur préparation |
US3458522A (en) * | 1967-05-17 | 1969-07-29 | Sandoz Ag | 4-piperidine substituted benzocycloheptaoxazoles and benzocycloheptathiazoles |
US3485846A (en) * | 1967-06-30 | 1969-12-23 | Eugene E Galantay | Benzocycloheptaimidazoles |
US3442903A (en) * | 1967-08-30 | 1969-05-06 | Sandoz Ag | Certain aminopropylidenebenzo(5,6)cyclohepta(1,2-d)thiazoles |
CH531000A (de) * | 1970-03-11 | 1972-11-30 | Sandoz Ag | Verfahren zur Herstellung neuer Benzocycloheptathiophene |
US3960894A (en) * | 1972-01-24 | 1976-06-01 | Sandoz Ltd. | 9-Bromo-or chloro-9,10-dihydro-10-dihydro-10-alkoxy-4H-benzo[4,5]cyclo-hepta[1,2-b]thiophen-4-ones |
US3994915A (en) * | 1972-06-30 | 1976-11-30 | Sandoz, Inc. | Preparation of substituted oxazoles |
CH579077A5 (en) * | 1972-08-17 | 1976-08-31 | Sandoz Ag | Antiallergic benzo(4,5) cyclohepta(1,2-b)-thiophene derivs - prepd by reacting 4-(4-piperidinylidene)-4 H-benzo(4,5)6 cyclohepta(1,2-b)thiophen-9(10H)-one with a benz(hydr)yl halide |
US4148903A (en) * | 1977-07-28 | 1979-04-10 | Merck & Co., Inc. | Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines |
US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
US4355036A (en) * | 1980-06-19 | 1982-10-19 | Schering Corporation | Tricyclic-substituted piperidine antihistamines |
ATE13297T1 (de) * | 1980-09-02 | 1985-06-15 | Sandoz Ag | Piperidyliden-derivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
US4596809A (en) * | 1985-03-25 | 1986-06-24 | Schering Corporation | Substituted 1,8-naphthyridinones, useful as anti-allergic agents |
US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
DE68916699T2 (de) * | 1988-04-28 | 1994-12-01 | Schering Corp | Benzopyridopiperidin, -piperidyliden und -piperazin-Verbindungen, Zusammensetzungen, Methoden zur Herstellung und Verwendung. |
JP2511550B2 (ja) * | 1988-04-28 | 1996-06-26 | シェリング・コーポレーション | 融合多環式化合物、組成物、製造方法およびpaf拮抗、抗ヒスタミンおよび/または抗炎症剤としてのその使用 |
CA2004211A1 (fr) * | 1988-11-30 | 1990-05-31 | Masataka Syoji | Derives de piperidine et hypotenseurs les contenant |
-
1991
- 1991-10-04 EP EP91920026A patent/EP0552292B1/fr not_active Expired - Lifetime
- 1991-10-04 WO PCT/US1991/007156 patent/WO1992006981A1/fr active Search and Examination
- 1991-10-04 AT AT91920026T patent/ATE124045T1/de not_active IP Right Cessation
- 1991-10-04 DE DE69110685T patent/DE69110685T2/de not_active Expired - Fee Related
- 1991-10-04 JP JP3518357A patent/JPH089616B2/ja not_active Expired - Lifetime
- 1991-10-04 CA CA002093797A patent/CA2093797C/fr not_active Expired - Fee Related
- 1991-10-04 AU AU89025/91A patent/AU8902591A/en not_active Abandoned
- 1991-10-04 US US08/039,038 patent/US5393753A/en not_active Expired - Fee Related
-
1996
- 1996-10-03 HK HK186696A patent/HK186696A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0552292A1 (fr) | 1993-07-28 |
DE69110685D1 (de) | 1995-07-27 |
EP0552292B1 (fr) | 1995-06-21 |
CA2093797A1 (fr) | 1992-04-11 |
WO1992006981A1 (fr) | 1992-04-30 |
JPH089616B2 (ja) | 1996-01-31 |
US5393753A (en) | 1995-02-28 |
CA2093797C (fr) | 1998-09-22 |
DE69110685T2 (de) | 1995-11-09 |
ATE124045T1 (de) | 1995-07-15 |
AU8902591A (en) | 1992-05-20 |
JPH05508661A (ja) | 1993-12-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |