HK1256855A1 - 用於提供已存檔樣本所衍生的dna片段的方法 - Google Patents
用於提供已存檔樣本所衍生的dna片段的方法Info
- Publication number
- HK1256855A1 HK1256855A1 HK18115941.8A HK18115941A HK1256855A1 HK 1256855 A1 HK1256855 A1 HK 1256855A1 HK 18115941 A HK18115941 A HK 18115941A HK 1256855 A1 HK1256855 A1 HK 1256855A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- dna fragments
- fragments derived
- providing dna
- archived sample
- archived
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61469704P | 2004-09-30 | 2004-09-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1256855A1 true HK1256855A1 (zh) | 2019-10-04 |
Family
ID=36143114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18115941.8A HK1256855A1 (zh) | 2004-09-30 | 2017-02-23 | 用於提供已存檔樣本所衍生的dna片段的方法 |
Country Status (5)
Country | Link |
---|---|
US (3) | US8679745B2 (zh) |
EP (5) | EP3061833B1 (zh) |
ES (4) | ES2668911T3 (zh) |
HK (1) | HK1256855A1 (zh) |
WO (1) | WO2006039563A2 (zh) |
Families Citing this family (39)
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US7601497B2 (en) | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
DE10338308B4 (de) | 2003-08-15 | 2006-10-19 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungen in DNA |
EP3061833B1 (en) * | 2004-09-30 | 2018-03-14 | Epigenomics AG | Method for providing dna fragments derived from an archived sample |
US7932027B2 (en) * | 2005-02-16 | 2011-04-26 | Epigenomics Ag | Method for determining the methylation pattern of a polynucleic acid |
DE102005034628B4 (de) * | 2005-07-19 | 2007-08-23 | Epigenomics Ag | Verfahren zur Untersuchung von Cytosin-Methylierungen in DNA |
US8768629B2 (en) * | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
IL282783B2 (en) * | 2006-05-18 | 2023-09-01 | Caris Mpi Inc | A system and method for determining a personalized medical intervention for a disease stage |
DK3101141T3 (da) | 2007-06-08 | 2020-02-03 | Epigenomics Ag | Fremgangsmåde til methyleringsanalyse |
US9115386B2 (en) | 2008-09-26 | 2015-08-25 | Children's Medical Center Corporation | Selective oxidation of 5-methylcytosine by TET-family proteins |
CN106153918A (zh) * | 2008-10-14 | 2016-11-23 | 卡里斯Mpi公司 | 描绘肿瘤类型生物标志模式和特征集的基因靶和基因表达的蛋白靶 |
US8288520B2 (en) | 2008-10-27 | 2012-10-16 | Qiagen Gaithersburg, Inc. | Fast results hybrid capture assay and system |
EP3722810A3 (en) * | 2009-02-11 | 2021-01-13 | Caris MPI, Inc. | Molecular profiling of tumors |
US9797000B2 (en) | 2009-05-01 | 2017-10-24 | Qiagen Gaithersburg Inc. | Non-target amplification method for detection of RNA splice-forms in a sample |
DE202009018981U1 (de) * | 2009-07-01 | 2015-03-11 | Axagarius Gmbh & Co. Kg | Verwendung eines Kits für die Isolierung von Biomolekülen aus biologischen Proben sowie Kit dafür |
EP2478087B1 (en) * | 2009-09-14 | 2017-01-18 | QIAGEN Gaithersburg, Inc. | Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media |
CN102822189B (zh) | 2010-01-29 | 2016-06-29 | 奇亚根盖瑟斯堡股份有限公司 | 用于核酸的序列特异性纯化和多重复合体分析(multiplex analysis)的方法和组合物 |
JP2013517803A (ja) | 2010-01-29 | 2013-05-20 | キアジェン ゲイサーズバーグ インコーポレイテッド | サンプル中のhpvの存在を決定および確認する方法 |
JP2013528049A (ja) | 2010-05-19 | 2013-07-08 | キアゲン ガイサーズバーグ アイエヌシー. | 核酸の配列特異的な精製及び多重分析のための方法及び組成物 |
AU2011258501B2 (en) | 2010-05-25 | 2016-07-07 | Qiagen Gaithersburg, Inc. | Fast results hybrid capture assay and associated strategically-truncated probes |
EP2395082A1 (en) * | 2010-06-14 | 2011-12-14 | QIAGEN GmbH | Extraction of nucleic acids from wax-embedded samples |
US9885092B2 (en) | 2011-02-24 | 2018-02-06 | Qiagen Gaithersburg Inc. | Materials and methods for detection of HPV nucleic acids |
JP6273198B2 (ja) | 2011-03-28 | 2018-01-31 | ジェロン・コーポレーションGeron Corporation | 定量的pcrによる、ホルマリン固定パラフィン包埋(ffpe)試料におけるテロメア長測定 |
ES2669214T3 (es) | 2011-12-13 | 2018-05-24 | Oslo Universitetssykehus Hf | Procedimientos y kits para la detección de estado de metilación |
ES2675584T3 (es) * | 2012-01-30 | 2018-07-11 | Exact Sciences Development Company, Llc | Modificación de ADN en perlas magnéticas |
EP2925883B1 (en) | 2012-11-30 | 2018-03-28 | Cambridge Epigenetix Limited | Oxidising agent for modified nucleotides |
US9200327B2 (en) | 2012-11-30 | 2015-12-01 | Geron Corporation | Diagnostic markers for treating cell proliferative disorders with telomerase inhibitors |
USRE48665E1 (en) * | 2014-02-28 | 2021-08-03 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
US9771571B2 (en) | 2014-02-28 | 2017-09-26 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
GB2559919B (en) * | 2014-02-28 | 2018-11-14 | Gen Probe Inc | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
US9771572B2 (en) | 2014-02-28 | 2017-09-26 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
JP6681414B2 (ja) | 2015-06-10 | 2020-04-15 | バイオカーティス エヌ ヴイ | メチル化dnaの改善された検出 |
US11459573B2 (en) | 2015-09-30 | 2022-10-04 | Trustees Of Boston University | Deadman and passcode microbial kill switches |
CN109804086B (zh) | 2016-08-10 | 2023-06-13 | 格里尔公司 | 制备双标签dna库用于亚硫酸盐转化定序的方法 |
DE102019118332B4 (de) * | 2019-07-07 | 2022-04-07 | Ist Innuscreen Gmbh | Verfahren und testkit zur bisulfitmodifizierung von dna |
EP4013896A4 (en) * | 2019-08-12 | 2023-09-20 | Baylor College of Medicine | PROTEOGENOMIC METHODS FOR CANCER DIAGNOSIS |
CN113186185B (zh) * | 2020-01-14 | 2023-05-26 | 东北林业大学 | 一种从哺乳动物粪便中高效富集宿主dna的方法 |
JP2023535636A (ja) | 2020-07-30 | 2023-08-18 | ケンブリッジ エピジェネティックス リミテッド | 核酸解析のための組成物および方法 |
CN117915922A (zh) * | 2021-04-27 | 2024-04-19 | 芝加哥大学 | 与假尿苷和5-羟甲基胞嘧啶的修饰和检测相关的组合物和方法 |
DE102022113596B3 (de) * | 2022-05-30 | 2023-06-29 | Xebios Diagnostics Group GmbH | Verfahren und Kit zum gleichzeitigen Nachweis einer Mehrzahl unterschiedlicher Pathogene in einer Probe |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
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US5786146A (en) * | 1996-06-03 | 1998-07-28 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
DE19754482A1 (de) | 1997-11-27 | 1999-07-01 | Epigenomics Gmbh | Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke |
EP0953635B1 (en) * | 1998-04-28 | 2012-08-29 | Ortho-Clinical Diagnostics, Inc. | Improved methods for extracting nucleic acids from tissue samples and paraffin-embedded tissues |
US6605432B1 (en) * | 1999-02-05 | 2003-08-12 | Curators Of The University Of Missouri | High-throughput methods for detecting DNA methylation |
DE19957827C2 (de) | 1999-11-25 | 2003-06-12 | Epigenomics Ag | Verwendung eines Oligomer-Arrays mit PNA- und/oder DNA-Oligomeren auf einer Oberfläche |
AU3074001A (en) * | 1999-12-09 | 2001-06-18 | Advanced Research And Technology Institute, Inc. | Fluorescent in situ rt-pcr |
US6248535B1 (en) | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
EP1728874B1 (en) * | 2000-03-24 | 2012-09-26 | Amgen Research (Munich) GmbH | Method for the preparation of an in vitro surrogate for identifying expressed genes in a test sample |
DE10029915B4 (de) | 2000-06-19 | 2005-06-16 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungen |
CA2421102A1 (en) | 2000-08-25 | 2002-03-07 | Lovelace Respiratory Research Institute | Nested methylation-specific polymerase chain reaction cancer detection method |
ES2299520T3 (es) | 2000-09-01 | 2008-06-01 | Epigenomics Ag | Procedimiento para la determinacion del grado de metilacion de determinadas citosinas en dna genomico en el contexto secuencial 5'-cpg-3'. |
DE10050942B4 (de) * | 2000-10-10 | 2005-11-17 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungen |
GB2369822A (en) | 2000-12-05 | 2002-06-12 | Genovar Diagnostics Ltd | Nucleic acid extraction method and kit |
DE10112515B4 (de) | 2001-03-09 | 2004-02-12 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungsmustern mit hoher Sensitivität |
WO2002086163A1 (en) | 2001-04-20 | 2002-10-31 | Karolinska Innovations Ab | Methods for high throughput genome analysis using restriction site tagged microarrays |
DE10154317B4 (de) | 2001-10-26 | 2005-06-09 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungen in immobilisierten DNA Proben |
EP1340818A1 (en) * | 2002-02-27 | 2003-09-03 | Epigenomics AG | Method and nucleic acids for the analysis of a colon cell proliferative disorder |
WO2003083107A1 (en) | 2002-03-25 | 2003-10-09 | The Board Of Trustees Of The University Of Arkansas | Cpg retrieval of dna from formalin-fixed pathology specimen for promoter methylation analysis |
US20040110138A1 (en) * | 2002-11-01 | 2004-06-10 | University Of Ottawa | Method for the detection of multiple genetic targets |
US7288373B2 (en) * | 2003-05-02 | 2007-10-30 | Human Genetic Signatures Pty Ltd. | Treatment of methylated nucleic acid |
DE10328813B4 (de) | 2003-06-20 | 2006-04-13 | Epigenomics Ag | Verfahren zur Untersuchung von Cytosin-Methylierungen in DNA-Sequenzen mittels triplexbildender Oligomere |
EP2088210A3 (en) | 2003-10-09 | 2009-11-18 | Epigenomics AG | Improved bisulfite conversion of DNA |
DE102004029700A1 (de) | 2004-06-15 | 2006-02-09 | Epigenomics Ag | Verfahren zur Quantifizierung methylierter DNA |
EP3061833B1 (en) | 2004-09-30 | 2018-03-14 | Epigenomics AG | Method for providing dna fragments derived from an archived sample |
DE102005007185A1 (de) | 2005-02-16 | 2006-08-17 | Epigenomics Ag | Verfahren zur Herstellung einer Mischung von Fragmenten einer Polynukleinsäure |
WO2006088978A1 (en) | 2005-02-16 | 2006-08-24 | Epigenomics, Inc. | Method for determining the methylation pattern of a polynucleic acid |
-
2005
- 2005-09-30 EP EP15201550.9A patent/EP3061833B1/en not_active Revoked
- 2005-09-30 ES ES15201550.9T patent/ES2668911T3/es active Active
- 2005-09-30 ES ES05802610.5T patent/ES2521115T3/es active Active
- 2005-09-30 EP EP05802610.5A patent/EP1794319B1/en active Active
- 2005-09-30 EP EP18156719.9A patent/EP3342877B1/en active Active
- 2005-09-30 ES ES11009790.4T patent/ES2564659T3/es active Active
- 2005-09-30 WO PCT/US2005/035317 patent/WO2006039563A2/en active Application Filing
- 2005-09-30 EP EP11009790.4A patent/EP2458015B1/en not_active Revoked
- 2005-09-30 US US11/664,367 patent/US8679745B2/en active Active
- 2005-09-30 ES ES18156719T patent/ES2787454T3/es active Active
-
2006
- 2006-09-19 EP EP06805772A patent/EP1977002A1/en not_active Withdrawn
-
2013
- 2013-12-02 US US14/094,667 patent/US8962246B2/en active Active
-
2015
- 2015-02-23 US US14/628,892 patent/US20150176062A1/en not_active Abandoned
-
2017
- 2017-02-23 HK HK18115941.8A patent/HK1256855A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US20150176062A1 (en) | 2015-06-25 |
EP1794319B1 (en) | 2014-08-13 |
ES2668911T3 (es) | 2018-05-23 |
EP1977002A1 (en) | 2008-10-08 |
WO2006039563A3 (en) | 2006-09-28 |
EP3342877B1 (en) | 2020-01-29 |
ES2787454T3 (es) | 2020-10-16 |
EP3342877A1 (en) | 2018-07-04 |
US20140087449A1 (en) | 2014-03-27 |
WO2006039563A2 (en) | 2006-04-13 |
US8679745B2 (en) | 2014-03-25 |
EP3061833A1 (en) | 2016-08-31 |
EP2458015B1 (en) | 2015-12-23 |
US8962246B2 (en) | 2015-02-24 |
EP2458015A1 (en) | 2012-05-30 |
EP1794319A4 (en) | 2009-10-21 |
EP1794319A2 (en) | 2007-06-13 |
EP3061833B1 (en) | 2018-03-14 |
US20080220418A1 (en) | 2008-09-11 |
ES2564659T3 (es) | 2016-03-28 |
ES2521115T3 (es) | 2014-11-12 |
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