HK1256242A1 - 吲哚化合物以及制备和使用该化合物的方法 - Google Patents

吲哚化合物以及制备和使用该化合物的方法 Download PDF

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Publication number
HK1256242A1
HK1256242A1 HK18115278.1A HK18115278A HK1256242A1 HK 1256242 A1 HK1256242 A1 HK 1256242A1 HK 18115278 A HK18115278 A HK 18115278A HK 1256242 A1 HK1256242 A1 HK 1256242A1
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Hong Kong
Prior art keywords
compounds
making
methods
benzazole
compositions
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HK18115278.1A
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English (en)
Chinese (zh)
Inventor
Rose Yen
Yan Chen
Rajinder Singh
Vanessa Taylor
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Rigel Pharmaceuticals, Inc.
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Application filed by Rigel Pharmaceuticals, Inc. filed Critical Rigel Pharmaceuticals, Inc.
Publication of HK1256242A1 publication Critical patent/HK1256242A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Epidemiology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
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  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
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  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
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HK18115278.1A 2015-08-04 2016-08-02 吲哚化合物以及制备和使用该化合物的方法 HK1256242A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562200778P 2015-08-04 2015-08-04
US62/200,778 2015-08-04
PCT/US2016/045176 WO2017023941A1 (en) 2015-08-04 2016-08-02 Benzazole compounds and methods for making and using the compounds

Publications (1)

Publication Number Publication Date
HK1256242A1 true HK1256242A1 (zh) 2019-09-20

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HK18115278.1A HK1256242A1 (zh) 2015-08-04 2016-08-02 吲哚化合物以及制备和使用该化合物的方法

Country Status (8)

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US (4) US10065946B2 (https=)
EP (2) EP3719016A1 (https=)
JP (2) JP6994454B2 (https=)
CA (1) CA2993661A1 (https=)
DK (1) DK3331879T3 (https=)
ES (1) ES2811136T3 (https=)
HK (1) HK1256242A1 (https=)
WO (1) WO2017023941A1 (https=)

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CN112043696B (zh) * 2020-08-26 2023-02-24 深圳市第二人民医院(深圳市转化医学研究院) Ido-1抑制剂在制备治疗骨性关节炎药物中的应用
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KR20240004476A (ko) 2021-04-08 2024-01-11 쿠리스 인코퍼레이션 암 치료를 위한 병용 요법
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