HK1254619A1 - 使用導電聚合物的游離dna捕獲平台以及該平台的應用 - Google Patents

使用導電聚合物的游離dna捕獲平台以及該平台的應用

Info

Publication number
HK1254619A1
HK1254619A1 HK18113585.4A HK18113585A HK1254619A1 HK 1254619 A1 HK1254619 A1 HK 1254619A1 HK 18113585 A HK18113585 A HK 18113585A HK 1254619 A1 HK1254619 A1 HK 1254619A1
Authority
HK
Hong Kong
Prior art keywords
platform
cell
conductive polymer
free dna
dna capture
Prior art date
Application number
HK18113585.4A
Other languages
English (en)
Inventor
曹榮南
李銀淑
Original Assignee
國立癌症中心
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 國立癌症中心 filed Critical 國立癌症中心
Publication of HK1254619A1 publication Critical patent/HK1254619A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/12—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/026—Wholly aromatic polyamines
    • C08G73/0266—Polyanilines or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/0605—Polycondensates containing five-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms
    • C08G73/0611—Polycondensates containing five-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms with only one nitrogen atom in the ring, e.g. polypyrroles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
HK18113585.4A 2015-06-23 2018-10-23 使用導電聚合物的游離dna捕獲平台以及該平台的應用 HK1254619A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020150089267A KR101701618B1 (ko) 2015-06-23 2015-06-23 전도성 고분자를 이용한 세포 유리 ｄｎａ 검출용 구조체 및 이의 용도
PCT/KR2016/006728 WO2016209011A1 (ko) 2015-06-23 2016-06-23 전도성 고분자를 이용한 세포 유리 dna 검출용 구조체 및 이의 용도

Publications (1)

Publication Number Publication Date
HK1254619A1 true HK1254619A1 (zh) 2019-07-26

Family

ID=57585770

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18113585.4A HK1254619A1 (zh) 2015-06-23 2018-10-23 使用導電聚合物的游離dna捕獲平台以及該平台的應用

Country Status (7)

Country Link
US (2) US20170051275A1 (zh)
EP (1) EP3315607B1 (zh)
JP (1) JP6670860B2 (zh)
KR (1) KR101701618B1 (zh)
CN (1) CN107980061A (zh)
HK (1) HK1254619A1 (zh)
WO (1) WO2016209011A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108330171A (zh) * 2017-09-27 2018-07-27 天津诺禾医学检验所有限公司 检测egfr基因第19号外显子缺失突变的试剂盒、方法及其应用
KR102249506B1 (ko) 2017-10-30 2021-05-11 주식회사 인퓨전텍 동형2기능성 이미도에스터를 이용한 액체생검 유래 생체물질의 추출 방법
JP7239973B2 (ja) * 2017-12-19 2023-03-15 国立大学法人山口大学 前癌病変又は癌の有無の予測を補助する方法
WO2019178346A1 (en) * 2018-03-14 2019-09-19 The Trustees Of The University Of Pennsylvania Enrichment of nucleic acids
KR102072735B1 (ko) * 2018-06-01 2020-02-03 주식회사 제놉시 불안정한 세포유리 dna 검출 방법 및 이를 이용한 장치
JP2022528278A (ja) * 2019-04-05 2022-06-09 ジェノプシー インコーポレイテッド Ｃｆｄｎａを用いたがん診断方法
US20230183811A1 (en) * 2020-05-14 2023-06-15 Georgia Tech Research Corporation Methods of detecting the efficacy of anticancer agents
KR102552632B1 (ko) * 2020-11-06 2023-07-06 사회복지법인 삼성생명공익재단 중추신경계 림프종을 진단하기 위한 마커, 이를 포함하는 중추신경계 림프종 진단 키트 및 중추신경계 림프종을 진단하는 방법
US20240084286A1 (en) * 2021-01-25 2024-03-14 The Broad Institute, Inc. Methods and compositions for increasing the concentration of cell free dna
CN115253682B (zh) * 2022-07-29 2024-02-02 烟台至公生物医药科技有限公司 一种膀胱癌细胞捕获装置及捕获方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776672A (en) * 1990-09-28 1998-07-07 Kabushiki Kaisha Toshiba Gene detection method
US5440025A (en) * 1992-03-12 1995-08-08 University Of Massachusetts At Lowell Process for separating nucleic acid polymers
BR9907852A (pt) 1998-02-12 2000-10-24 Immunivest Corp Processos para detectar e enumerar células raras e cancerosas em uma população celular mista, para diagnosticar câncer de estágio precoce em um paciente de teste, para determinar a probabilidade de recorrência de câncer em um paciente humano anteriormente tratado de câncer, para distinguir um carcinoma confinado ao órgão de um carcinoma com propriedades metastáticas, para acompanhar a situação de remissão em um paciente humano com câncer que passa pelo tratamento de terapia contra o câncer e para aumentar quantidades de células epiteliais circulantes em uma amostra de sangue, partìcula magnética revestida, composição, conjuntos de teste para avaliar uma amostra de paciente quanto a presença de células raras circulantes, quanto a presença de células de tumor circulantes, quanto a presença de células de câncer de mama circulantes, quanto a presença de células de câncer de próstata circulantes, quanto a presença de células de câncer de cólon circulantes, quanto a presença de células de câncer de bexiga circulantes e para monitorar um paciente quanto a recorrência de câncer, e, fração de sangue periférico enriquecido quanto a células neoplásticas circulantes
US6855426B2 (en) 2001-08-08 2005-02-15 Nanoproducts Corporation Methods for producing composite nanoparticles
JP4593557B2 (ja) 2003-02-27 2010-12-08 ベリデックス・リミテッド・ライアビリティ・カンパニー 循環腫瘍細胞（ｃｔｃ）：転移癌患者における増悪までの時間、生存および療法に対する応答の早期評価
DE10311315A1 (de) * 2003-03-14 2004-09-30 Apibio Sas Verfahren und Vorrichtung zur Detektion von Biomolekülen
US7910064B2 (en) 2003-06-03 2011-03-22 Nanosys, Inc. Nanowire-based sensor configurations
WO2006042276A2 (en) * 2004-10-12 2006-04-20 The Regents Of The University Of California Electrochemically fabricated conducting polymer nanowire sensors
US8034222B2 (en) * 2004-10-26 2011-10-11 The Regents Of The University Of California Conducting polymer nanowire sensors
JP2009500609A (ja) * 2005-06-30 2009-01-08 アプレラ コーポレーション 導電性ポリマーを含む多孔質コンポジット電極
KR100700090B1 (ko) * 2005-09-23 2007-03-28 삼성전자주식회사 이온투과성 폴리머로 코팅된 전극을 이용한 핵산 정제 방법및 그 장치
KR100730350B1 (ko) 2005-10-17 2007-06-19 삼성전자주식회사 표면처리된 나노포어를 이용한 ｄｎａ 검출방법 및검출장치
RU2429486C2 (ru) 2006-06-02 2011-09-20 Пфайзер Продактс Инк. Анализ циркулирующих опухолевых клеток
ES2524458T3 (es) 2006-10-18 2014-12-09 Periness Ltd. DNasa para el tratamiento de la subfertilidad masculina
KR100940598B1 (ko) * 2007-10-12 2010-02-04 부산대학교 산학협력단 Ｄｎａ검출용 마이크로칩 및 이를 이용한 검출방법
US8070928B2 (en) * 2007-12-31 2011-12-06 Intel Corporation Nanofabricated structures for electric field-assisted nucleic acid extraction
US20100041048A1 (en) * 2008-07-31 2010-02-18 The Johns Hopkins University Circulating Mutant DNA to Assess Tumor Dynamics
JP5080434B2 (ja) 2008-12-05 2012-11-21 ベリデックス・リミテッド・ライアビリティ・カンパニー 生物学的試料から標的生体部分を単離する方法およびそのためのキット
WO2010151817A1 (en) * 2009-06-25 2010-12-29 The Regents Of The University Of California Probe immobilization and signal amplification for polymer-based biosensor
JP5704590B2 (ja) 2010-02-05 2015-04-22 国立大学法人東京農工大学 サイズ選択マイクロキャビティアレイを用いた循環腫瘍細胞の検出
CN101812176B (zh) * 2010-04-13 2012-01-25 无锡中美亿芯生物科技有限公司 一种具有生物活性的导电聚苯胺及其制备方法和应用
WO2012162563A2 (en) * 2011-05-24 2012-11-29 The Regents Of The University Of California Method for exosomal biomarker detection by electric field-induced release and measurement
JP5854456B2 (ja) 2011-08-23 2016-02-09 日立化成株式会社 癌細胞濃縮フィルター
KR101473078B1 (ko) * 2013-01-02 2014-12-17 연세대학교 산학협력단 암 진단 및 치료용 유-무기 나노복합체
US9999856B2 (en) * 2013-07-26 2018-06-19 General Electric Company Methods for electroelution of biomolecules
KR101545160B1 (ko) * 2013-11-25 2015-08-19 국립암센터 전도성 고분자를 포함하는 세포의 검출 및 회수용 조성물
CN106459966A (zh) * 2014-04-08 2017-02-22 生物动力学公司 用于生物材料的分离的改进的装置

Also Published As

Publication number Publication date
EP3315607A4 (en) 2018-12-26
WO2016209011A1 (ko) 2016-12-29
KR101701618B1 (ko) 2017-02-13
US20190376056A1 (en) 2019-12-12
CN107980061A (zh) 2018-05-01
EP3315607B1 (en) 2021-05-26
US11352616B2 (en) 2022-06-07
US20170051275A1 (en) 2017-02-23
KR20170000258A (ko) 2017-01-02
JP2018522550A (ja) 2018-08-16
JP6670860B2 (ja) 2020-04-01
EP3315607A1 (en) 2018-05-02

Similar Documents

Publication Publication Date Title
HK1254619A1 (zh) 使用導電聚合物的游離dna捕獲平台以及該平台的應用
IL275307B (en) Syntac polypeptides and their uses
HUE053797T2 (hu) Csatlakozó és alkatrész és a csatlakozó használata
GB2588261B (en) Apparatus, use of the apparatus and arrangement
EP3091603A4 (en) Electrolytic solution and electrochemical device
SG11201607082PA (en) New tetracyano-anthraquino-dimethane polymers and use thereof
HK1250146A1 (zh) 抗前-bcr拮抗劑和方法
EP3357934B8 (en) Polymer particles and use thereof
HK1232241A1 (zh) 聚合物顆粒及其用途
EP3168916A4 (en) Electrolytic solution and electrochemical device
EP3168250A4 (en) Fluorine-atom-containing polymer and use thereof
GB2543713B (en) Polymeric proteins and uses thereof
GB201420222D0 (en) Molecular probes and methods using the same
GB201410031D0 (en) Polypeptides and uses thereof
HK1223194A1 (zh) 表面安裝技術器件及相關方法
GB201510461D0 (en) New polymers and methods
GB201420223D0 (en) Molecular probes and methods using the same
IL251518A0 (en) Astaxanthin-based polymers and their uses
GB201420221D0 (en) Molecular probes and methods using the same
GB2545167B (en) Cloches and use thereof
PL3229772T3 (pl) 6-arylo-9-glikozylopuryny i ich zastosowanie
GB201504773D0 (en) Methods and devices used in roofing
TH1401004956B (th) ตัวต่อและอุปกรณ์ที่มีตัวต่อ
ZA201507311B (en) Hinge arrangement and device comprising the arrangement
GB201506803D0 (en) Connector and assembly including the same