HK1250484A1 - 用於治疗胰腺炎的吉卡宾和衍生物 - Google Patents

用於治疗胰腺炎的吉卡宾和衍生物 Download PDF

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Publication number
HK1250484A1
HK1250484A1 HK18109899.3A HK18109899A HK1250484A1 HK 1250484 A1 HK1250484 A1 HK 1250484A1 HK 18109899 A HK18109899 A HK 18109899A HK 1250484 A1 HK1250484 A1 HK 1250484A1
Authority
HK
Hong Kong
Prior art keywords
compound
pancreatitis
subject
gemcabene
administered
Prior art date
Application number
HK18109899.3A
Other languages
English (en)
Chinese (zh)
Inventor
Charles L. Bisgaier
Original Assignee
Gemphire Therapeutics Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gemphire Therapeutics Inc. filed Critical Gemphire Therapeutics Inc.
Publication of HK1250484A1 publication Critical patent/HK1250484A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18109899.3A 2010-12-27 2018-08-01 用於治疗胰腺炎的吉卡宾和衍生物 HK1250484A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201061427236P 2010-12-27 2010-12-27
US61/427236 2010-12-27

Publications (1)

Publication Number Publication Date
HK1250484A1 true HK1250484A1 (zh) 2018-12-21

Family

ID=45498140

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18109899.3A HK1250484A1 (zh) 2010-12-27 2018-08-01 用於治疗胰腺炎的吉卡宾和衍生物

Country Status (14)

Country Link
US (1) US8846761B2 (https=)
EP (2) EP3170495B1 (https=)
JP (3) JP2014509305A (https=)
CN (2) CN103442707A (https=)
AU (1) AU2011352449B2 (https=)
CA (1) CA2822921C (https=)
DK (1) DK2658536T3 (https=)
ES (1) ES2608177T3 (https=)
HK (1) HK1250484A1 (https=)
HU (1) HUE031004T2 (https=)
MX (1) MX337593B (https=)
PL (1) PL2658536T3 (https=)
PT (1) PT2658536T (https=)
WO (1) WO2012092103A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016077832A2 (en) 2014-11-14 2016-05-19 Gemphire Therapeutics Inc. PROCESSES AND INTERMEDIATES FOR PREPARING α,ω-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS
AU2016348638A1 (en) * 2015-11-06 2018-06-07 Gemphire Therapeutics Inc. Gemcabene combinations for the treatment of cardiovascular disease
EP3612171A4 (en) 2017-04-18 2020-10-21 Gemphire Therapeutics Inc. GEMCABENE, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, COMPOSITIONS THEREOF AND PROCEDURES FOR THE USE OF THE SAME

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3737289A (en) 1988-06-06 1990-01-05 Okamoto, Shosuke Agent for treating pancreatitis or the like
US5648387A (en) 1995-03-24 1997-07-15 Warner-Lambert Company Carboxyalkylethers, formulations, and treatment of vascular diseases
US20020103252A1 (en) 1997-12-12 2002-08-01 Bisgaier Charles Larry Statin-carboxyalkylether combinations
US20030105154A1 (en) * 2001-10-24 2003-06-05 Bisgaier Charles Larry Statin-carboxyalkylether combinations
US6861555B2 (en) 2000-01-25 2005-03-01 Warner-Lambert Company Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith
MXPA01009893A (es) 1999-04-01 2003-07-28 Esperion Therapeutics Inc Compuestos con eter, composiciones y usos de estos.
IL155215A0 (en) 2000-10-11 2003-11-23 Esperion Therapeutics Inc Ether compounds and compositions for cholesterol management and related uses
US6645170B2 (en) 2001-03-05 2003-11-11 Bioject Medical Technologies, Inc. Simplified disposable needle-free injection apparatus and method
US20040229954A1 (en) * 2003-05-16 2004-11-18 Macdougall Diane Elaine Selective manipulation of triglyceride, HDL and LDL parameters with 6-(5-carboxy-5-methyl-hexyloxy)-2,2-dimethylhexanoic acid monocalcium salt
US7345190B2 (en) 2003-11-12 2008-03-18 Ssv Therapeutics, Inc. Carnitine conjugates as dual prodrugs and uses thereof

Also Published As

Publication number Publication date
EP3170495A1 (en) 2017-05-24
CA2822921C (en) 2018-07-17
AU2011352449B2 (en) 2015-06-18
US20120165411A1 (en) 2012-06-28
CN107648210A (zh) 2018-02-02
WO2012092103A1 (en) 2012-07-05
PL2658536T3 (pl) 2017-04-28
AU2011352449A1 (en) 2013-07-11
CN103442707A (zh) 2013-12-11
US8846761B2 (en) 2014-09-30
JP6207560B2 (ja) 2017-10-04
PT2658536T (pt) 2016-12-22
JP2018027953A (ja) 2018-02-22
EP2658536B1 (en) 2016-10-19
ES2608177T3 (es) 2017-04-06
MX337593B (es) 2016-03-11
HUE031004T2 (en) 2017-06-28
DK2658536T3 (en) 2017-01-09
EP2658536A1 (en) 2013-11-06
EP3170495B1 (en) 2023-04-26
JP2014509305A (ja) 2014-04-17
MX2013007310A (es) 2013-10-25
JP2016028075A (ja) 2016-02-25
CA2822921A1 (en) 2012-07-05

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