HK1246329A1 - 半胱氨酸連接的納米抗體二聚體 - Google Patents
半胱氨酸連接的納米抗體二聚體Info
- Publication number
- HK1246329A1 HK1246329A1 HK18105949.1A HK18105949A HK1246329A1 HK 1246329 A1 HK1246329 A1 HK 1246329A1 HK 18105949 A HK18105949 A HK 18105949A HK 1246329 A1 HK1246329 A1 HK 1246329A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- dimers
- cysteine linked
- nanobody
- linked nanobody
- cysteine
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
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US201462094179P | 2014-12-19 | 2014-12-19 | |
US201562140611P | 2015-03-31 | 2015-03-31 | |
PCT/EP2015/080536 WO2016097313A1 (en) | 2014-12-19 | 2015-12-18 | Cysteine linked nanobody dimers |
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CA (1) | CA2971278C (zh) |
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ES2777928T3 (es) * | 2011-10-18 | 2020-08-06 | Institut National De Rech Pour L'agriculture L'alimentation Et L'environnement | Uso de derivado de avermectina para aumentar la biodisponibilidad y eficacia de lactonas macrocíclicas |
AU2016214317B2 (en) * | 2015-02-05 | 2022-01-13 | Ablynx N.V. | Nanobody dimers linked via C-terminally engineered cysteins |
KR101841339B1 (ko) * | 2015-03-31 | 2018-03-22 | 한양대학교 산학협력단 | 항암 활성을 갖는 펩티드, 이를 유효성분으로 함유하는 암 예방 및 치료용 약학 조성물 및 건강기능식품 조성물 |
KR101723292B1 (ko) * | 2015-05-06 | 2017-04-04 | 서울대학교산학협력단 | Kai1 폴리펩타이드 또는 이를 코딩하는 유전자를 포함하는 혈관신생 억제용 조성물 및 이의 용도 |
US9765117B2 (en) * | 2015-08-24 | 2017-09-19 | Romek Figa | Peptides for treating cancer |
GB201520558D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520568D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd | Peptides |
GB201520570D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520539D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201604468D0 (en) * | 2016-03-16 | 2016-04-27 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520557D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520595D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520550D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520543D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
RU2648164C1 (ru) * | 2016-12-19 | 2018-03-22 | Федеральное государственное учреждение науки Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Селективный бифункциональный препарат на основе фрагментов одноцепочечных антител верблюжьих, нацеленный на опухолевые рецепторы cd47/erbb2, предназначенный для терапии злокачественных новообразований |
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CN113150152B (zh) * | 2021-04-13 | 2022-08-09 | 西安交通大学 | 一种人源t细胞表面抑制性分子的特异性纳米抗体及其应用 |
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CN107406497A (zh) | 2017-11-28 |
CA2971278A1 (en) | 2016-06-23 |
PT3233910T (pt) | 2020-03-17 |
ES2772348T3 (es) | 2020-07-07 |
PL3233910T3 (pl) | 2020-06-01 |
US20170360955A1 (en) | 2017-12-21 |
WO2016097313A1 (en) | 2016-06-23 |
AU2015366284A1 (en) | 2017-06-29 |
US20230211006A1 (en) | 2023-07-06 |
AU2015366284B2 (en) | 2021-07-22 |
US11426468B2 (en) | 2022-08-30 |
CA2971278C (en) | 2023-09-19 |
JP6862343B2 (ja) | 2021-04-21 |
EP3233910B1 (en) | 2019-12-11 |
EP3233910A1 (en) | 2017-10-25 |
JP2018504383A (ja) | 2018-02-15 |
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