HK1245651A1 - Therapeutic agent for dry eye characterized by being to be dropped into eye of dry eye patient wearing soft contact lens - Google Patents

Therapeutic agent for dry eye characterized by being to be dropped into eye of dry eye patient wearing soft contact lens Download PDF

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Publication number
HK1245651A1
HK1245651A1 HK18105156.9A HK18105156A HK1245651A1 HK 1245651 A1 HK1245651 A1 HK 1245651A1 HK 18105156 A HK18105156 A HK 18105156A HK 1245651 A1 HK1245651 A1 HK 1245651A1
Authority
HK
Hong Kong
Prior art keywords
eye
soft contact
dry eye
ophthalmic solution
salt
Prior art date
Application number
HK18105156.9A
Other languages
English (en)
Chinese (zh)
Inventor
大下善弘
中泽仁志
松冈功
中澤仁志
神村明日香
松岡功
Original Assignee
Santen Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co., Ltd. filed Critical Santen Pharmaceutical Co., Ltd.
Publication of HK1245651A1 publication Critical patent/HK1245651A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK18105156.9A 2015-06-05 2016-06-03 Therapeutic agent for dry eye characterized by being to be dropped into eye of dry eye patient wearing soft contact lens HK1245651A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015114596 2015-06-05
JP2015114596 2015-06-05
PCT/JP2016/066590 WO2016195072A1 (ja) 2015-06-05 2016-06-03 ソフトコンタクトレンズが装用されたドライアイ患者の眼に点眼されるように用いられることを特徴とするドライアイ治療剤

Publications (1)

Publication Number Publication Date
HK1245651A1 true HK1245651A1 (en) 2018-08-31

Family

ID=57441364

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105156.9A HK1245651A1 (en) 2015-06-05 2016-06-03 Therapeutic agent for dry eye characterized by being to be dropped into eye of dry eye patient wearing soft contact lens

Country Status (11)

Country Link
US (3) US10729712B2 (enExample)
EP (1) EP3305301B1 (enExample)
JP (5) JP2017002035A (enExample)
KR (2) KR20180014768A (enExample)
CN (2) CN113143948A (enExample)
CA (1) CA2987882A1 (enExample)
ES (1) ES2999137T3 (enExample)
HK (1) HK1245651A1 (enExample)
RU (1) RU2742032C2 (enExample)
TW (1) TW201707710A (enExample)
WO (1) WO2016195072A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119114152A (zh) * 2017-06-17 2024-12-13 株式会社Acenet 自由基产生催化剂、自由基的制造方法、氧化反应产物的制造方法、药剂和农畜产用药剂
CN108853016A (zh) * 2018-09-26 2018-11-23 广州大光制药有限公司 一种地夸磷索钠滴眼液及其制备方法
CN114286670B (zh) * 2019-08-27 2024-01-16 参天制药株式会社 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物
CN113712909A (zh) * 2020-05-25 2021-11-30 南京帝昌医药科技有限公司 一种复方地夸磷索四钠滴眼液及其制备方法
KR102365008B1 (ko) * 2020-06-23 2022-02-23 주식회사태준제약 디쿠아포솔을 포함하는 점안 조성물
CN115996705A (zh) * 2020-06-23 2023-04-21 株式会社泰俊制药 包含地夸磷索的眼用组合物
CN116568287A (zh) * 2020-11-30 2023-08-08 学校法人近畿大学 泪膜破裂时间缩短型干眼症治疗剂及含有该治疗剂的滴眼剂
KR102548710B1 (ko) * 2020-12-24 2023-06-28 주식회사 종근당 디쿠아포솔 또는 이의 약제학적으로 허용가능한 염과 토코페롤을 함유하는 건성안 예방 또는 치료용 약제학적 조성물
JP7230169B2 (ja) * 2020-12-25 2023-02-28 参天製薬株式会社 ジクアホソルまたはその塩、銀塩およびイオン性等張化剤を含有する水性点眼液
CN114187994A (zh) * 2021-12-06 2022-03-15 上海泽充生物技术有限公司 一种提示干眼症患者定期滴眼并记录的系统

Family Cites Families (16)

* Cited by examiner, † Cited by third party
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US4029817A (en) * 1973-09-24 1977-06-14 Allergan Pharmaceuticals Soft contact lens preserving solutions
WO1997020578A1 (en) * 1995-12-04 1997-06-12 University Of Miami Non-preserved topical corticosteroid for treatment of dry eye, filamentary keratitis, and delayed tear clearance
US5900407A (en) 1997-02-06 1999-05-04 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with uridine triphosphates and related compounds
US5763447C1 (en) * 1996-07-23 2002-05-07 Inspire Pharmaceuticals Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds
AU721273B2 (en) 1996-09-20 2000-06-29 Bausch & Lomb Incorporated Method and composition for rewetting contact lenses and relieving eye dryness
US20040214754A1 (en) * 2001-10-03 2004-10-28 Ellis Edward J. Ophthalmic preparation containing glycomacropeptide
US20100130580A1 (en) * 2006-01-25 2010-05-27 Aciex Therapeutics, Inc. Formulations and Methods for Treating Dry Eye
CN102481268B (zh) 2009-06-25 2014-04-02 狮王株式会社 眼科用组合物和白浊、沉淀的抑制方法
JP5640492B2 (ja) * 2009-06-30 2014-12-17 ライオン株式会社 眼科用組成物及び白濁・沈殿抑制方法
PT2598119T (pt) * 2010-07-29 2018-12-17 Allergan Inc Soluções de brimonidina e timolol isentas de conservantes
AU2011299851A1 (en) * 2010-09-10 2013-04-04 Santen Pharmaceutical Co., Ltd. Agent for treatment of dry eye characterized by combining P2Y2 receptor agonist with hyaluronic acid or salt thereof, method for treating dry eye, and use of the P2Y2 receptor agonist and hyaluronic acid or salt thereof
CN103282039A (zh) 2010-12-28 2013-09-04 参天制药株式会社 含有地夸磷索的滴眼液及其制备方法、抑制不溶性析出物产生的方法
MX341189B (es) 2011-01-18 2016-08-09 Senju Pharma Co Composicion liquida y acousa de bromfenaco, que tiene efectividad conservadora.
SG11201405799TA (en) * 2012-03-26 2014-11-27 Santen Pharmaceutical Co Ltd Ophthalmic solution comprising diquafosol
JP5686454B1 (ja) * 2013-12-12 2015-03-18 株式会社メニコン コンタクトレンズ装着用液剤およびそれを用いたコンタクトレンズの屈折率向上方法
TWI709405B (zh) * 2014-12-25 2020-11-11 日商參天製藥股份有限公司 水性點眼液及其應用

Also Published As

Publication number Publication date
EP3305301C0 (en) 2024-11-27
KR20200079572A (ko) 2020-07-03
EP3305301B1 (en) 2024-11-27
JP2024014996A (ja) 2024-02-01
RU2017145545A (ru) 2019-07-09
TW201707710A (zh) 2017-03-01
RU2017145545A3 (enExample) 2019-11-21
JP2022093383A (ja) 2022-06-23
ES2999137T3 (en) 2025-02-24
US10729712B2 (en) 2020-08-04
JP2017002035A (ja) 2017-01-05
EP3305301A1 (en) 2018-04-11
EP3305301A4 (en) 2019-02-13
US20200254000A1 (en) 2020-08-13
US20210128601A1 (en) 2021-05-06
KR20180014768A (ko) 2018-02-09
US20180147230A1 (en) 2018-05-31
JP2025096568A (ja) 2025-06-26
CN113143948A (zh) 2021-07-23
US10918656B2 (en) 2021-02-16
WO2016195072A1 (ja) 2016-12-08
RU2742032C2 (ru) 2021-02-01
CA2987882A1 (en) 2016-12-08
CN107635565A (zh) 2018-01-26
JP2021073289A (ja) 2021-05-13

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