HK1244018A1 - 狂犬病毒g蛋白表位及與其特異性結合的中和狂犬病毒的結合分子 - Google Patents
狂犬病毒g蛋白表位及與其特異性結合的中和狂犬病毒的結合分子Info
- Publication number
- HK1244018A1 HK1244018A1 HK18103596.2A HK18103596A HK1244018A1 HK 1244018 A1 HK1244018 A1 HK 1244018A1 HK 18103596 A HK18103596 A HK 18103596A HK 1244018 A1 HK1244018 A1 HK 1244018A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- rabies virus
- binding molecule
- binds specifically
- protein epitope
- neutralising binding
- Prior art date
Links
- 241000711798 Rabies lyssavirus Species 0.000 title 2
- 230000003472 neutralizing effect Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/205—Rhabdoviridae, e.g. rabies virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20150082284 | 2015-06-10 | ||
PCT/KR2016/006145 WO2016200189A1 (ko) | 2015-06-10 | 2016-06-09 | 광견병 바이러스 g 단백질의 에피토프 및 이에 특이적으로 결합하는 광견병 바이러스 중화 결합 분자 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1244018A1 true HK1244018A1 (zh) | 2018-07-27 |
Family
ID=57503787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18103596.2A HK1244018A1 (zh) | 2015-06-10 | 2018-03-15 | 狂犬病毒g蛋白表位及與其特異性結合的中和狂犬病毒的結合分子 |
Country Status (5)
Country | Link |
---|---|
US (1) | US10722571B2 (zh) |
KR (1) | KR101969626B1 (zh) |
CN (1) | CN107709360B (zh) |
HK (1) | HK1244018A1 (zh) |
WO (1) | WO2016200189A1 (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11773155B2 (en) | 2018-08-09 | 2023-10-03 | Beijing Wisdomab Biotechnology Co., Ltd | Bispecific antibody against rabies virus, and application thereof |
CN113501873B (zh) * | 2021-07-07 | 2023-05-23 | 高光 | Rbv的蛋白结合分子及其用途 |
CN114748618A (zh) * | 2022-04-02 | 2022-07-15 | 重庆智翔金泰生物制药股份有限公司 | 包含针对狂犬病病毒g蛋白的双特异性抗体的药物制剂及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005023849A2 (en) * | 2003-09-04 | 2005-03-17 | Crucell Holland B.V. | Antigenic peptides of rabies virus and uses thereof |
KR101456770B1 (ko) * | 2004-05-27 | 2014-10-31 | 크루셀 홀란드 비.브이. | 광견병 바이러스를 중화시킬 수 있는 결합 분자 및 그 용도 |
SI1851315T1 (sl) * | 2005-02-02 | 2014-06-30 | University Of Massachusetts | Humana protitelesa proti steklini in njihova uporaba |
ATE471381T1 (de) | 2005-03-04 | 2010-07-15 | Celltrion Inc | Expressionsvektor für tierische zelle mit wenigstens einer kopie von mar-dna-sequenzen am 3'-ende des transkriptionsterminationsbereichs eines gens sowie verfahren zur expression eines fremdgens unter verwendung des vektors |
KR101495019B1 (ko) * | 2011-09-30 | 2015-02-24 | (주)셀트리온 | 광견병 바이러스를 중화시킬 수 있는 결합 분자 |
CN103374069B (zh) * | 2012-04-24 | 2015-06-03 | 中国科学院上海生命科学研究院 | 一种抗狂犬病毒的结合分子2e1 |
WO2015088256A1 (ko) * | 2013-12-12 | 2015-06-18 | (주)셀트리온 | 광견병 바이러스를 중화시킬 수 있는 결합 분자 |
-
2016
- 2016-06-09 CN CN201680033860.2A patent/CN107709360B/zh active Active
- 2016-06-09 US US15/735,068 patent/US10722571B2/en active Active
- 2016-06-09 WO PCT/KR2016/006145 patent/WO2016200189A1/ko active Application Filing
- 2016-06-09 KR KR1020160071948A patent/KR101969626B1/ko active IP Right Grant
-
2018
- 2018-03-15 HK HK18103596.2A patent/HK1244018A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US20190022211A1 (en) | 2019-01-24 |
CN107709360B (zh) | 2021-10-19 |
US10722571B2 (en) | 2020-07-28 |
KR101969626B1 (ko) | 2019-04-16 |
KR20160145508A (ko) | 2016-12-20 |
CN107709360A (zh) | 2018-02-16 |
WO2016200189A1 (ko) | 2016-12-15 |
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