HK1231401A1 - 治疗阿尔茨海默氏病的方法 - Google Patents

治疗阿尔茨海默氏病的方法 Download PDF

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Publication number
HK1231401A1
HK1231401A1 HK17105176.6A HK17105176A HK1231401A1 HK 1231401 A1 HK1231401 A1 HK 1231401A1 HK 17105176 A HK17105176 A HK 17105176A HK 1231401 A1 HK1231401 A1 HK 1231401A1
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HK
Hong Kong
Prior art keywords
antibody
seq
patient
hvr
agent
Prior art date
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HK17105176.6A
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English (en)
Chinese (zh)
Inventor
威廉姆．趙
威廉姆．赵
米歇爾．福瑞森漢
米歇尔．福瑞森汉
羅伯特．保羅
罗伯特．保罗
邁克爾．沃德
迈克尔．沃德
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健泰科生物技术公司
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Application filed by 健泰科生物技术公司 filed Critical 健泰科生物技术公司
Publication of HK1231401A1 publication Critical patent/HK1231401A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK17105176.6A 2014-02-08 2015-02-06 治疗阿尔茨海默氏病的方法 HK1231401A1 (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201461937472P 2014-02-08 2014-02-08
US61/937,472 2014-02-08
US201461971479P 2014-03-27 2014-03-27
US61/971,479 2014-03-27
US201462010259P 2014-06-10 2014-06-10
US62/010,259 2014-06-10
US201462081992P 2014-11-19 2014-11-19
US62/081,992 2014-11-19
PCT/US2015/014758 WO2015120233A1 (en) 2014-02-08 2015-02-06 Methods of treating alzheimer's disease

Publications (1)

Publication Number Publication Date
HK1231401A1 true HK1231401A1 (zh) 2017-12-22

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ID=52684643

Family Applications (1)

Application Number Title Priority Date Filing Date
HK17105176.6A HK1231401A1 (zh) 2014-02-08 2015-02-06 治疗阿尔茨海默氏病的方法

Country Status (19)

Country Link
US (3) US20150246963A1 (https=)
EP (2) EP3718563A1 (https=)
JP (4) JP6685912B2 (https=)
KR (4) KR20210121288A (https=)
CN (1) CN106163548A (https=)
AU (1) AU2015214058B2 (https=)
BR (1) BR112016018170A2 (https=)
CA (1) CA2938466C (https=)
CL (2) CL2016001979A1 (https=)
HK (1) HK1231401A1 (https=)
IL (1) IL246999B (https=)
MX (1) MX380252B (https=)
MY (1) MY179105A (https=)
NZ (1) NZ723884A (https=)
RU (1) RU2724190C2 (https=)
SG (2) SG11201606316XA (https=)
TW (1) TWI705824B (https=)
WO (1) WO2015120233A1 (https=)
ZA (1) ZA201605341B (https=)

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FI3347002T3 (fi) 2015-09-10 2023-08-10 Alzheon Inc Alzheimerin taudin hoitaminen tietyssä potilaspopulaatiossa
HK1257801A1 (zh) 2015-10-28 2019-11-01 宾夕法尼亚州大学信托人 用於基因治疗的腺伴随病毒载体的鞘内给药
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CA3026598A1 (en) * 2016-06-07 2017-12-14 Biogen International Neuroscience Gmbh Methods for treating alzheimer's disease
JP2019522033A (ja) * 2016-07-29 2019-08-08 バイオジェン チェサピーク エルエルシー アルツハイマー病治療に関連するアミロイド関連画像異常の治療または予防方法
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WO2019182319A1 (ko) * 2018-03-20 2019-09-26 (주)인벤티지랩 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물의 제조 방법 및 이의 제조 방법으로 제조된 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물
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US20200399352A1 (en) 2020-12-24
EP3102231B1 (en) 2019-09-11
JP2017511793A (ja) 2017-04-27
MY179105A (en) 2020-10-28
CN106163548A (zh) 2016-11-23
CL2016001979A1 (es) 2017-02-10
MX2016010173A (es) 2016-10-13
SG11201606316XA (en) 2016-08-30
JP2020073507A (ja) 2020-05-14
TWI705824B (zh) 2020-10-01
KR20210121288A (ko) 2021-10-07
SG10201913637RA (en) 2020-03-30
WO2015120233A1 (en) 2015-08-13
US20150246963A1 (en) 2015-09-03
AU2015214058B2 (en) 2020-07-09
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