US4401108A
(en)
|
1980-02-13 |
1983-08-30 |
Thomas Jefferson University |
Radioactive material loading, calibration and injection systems
|
SU1033181A1
(ru)
|
1982-02-02 |
1983-08-07 |
Томское Отделение Охтинского Ордена Ленина И Ордена Трудового Красного Знамени Научно-Производственного Объединения "Пластполимер" |
Способ обработки полимерного сорбента дл хроматографии
|
JPS6075530A
(ja)
|
1983-09-30 |
1985-04-27 |
Asahi Chem Ind Co Ltd |
金属元素の新しい分離精製方法
|
US4559175A
(en)
|
1984-04-19 |
1985-12-17 |
The United States Of America As Represented By The Secretary Of The Air Force |
Halo-substituted diphospha-s-triazines and their derivatives
|
US4885250A
(en)
|
1987-03-02 |
1989-12-05 |
E. I. Du Pont De Nemours And Company |
Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports
|
US5612016A
(en)
|
1988-04-01 |
1997-03-18 |
Immunomedics, Inc. |
Conjugates of antibodies and bifunctional ligands
|
US5169936A
(en)
|
1989-04-14 |
1992-12-08 |
Biogen, Inc. |
Protein purification on immobilized metal affinity resins effected by elution using a weak ligand
|
EP0455757B1
(en)
|
1989-08-04 |
1999-03-31 |
GRANDICS, Peter |
An integrated cell culture-protein purification system for the automated production and purification of cell culture products
|
US5244816A
(en)
|
1989-10-11 |
1993-09-14 |
Akzo N.V. |
Method for purifying chelator conjugated compounds
|
AU1742092A
(en)
|
1991-04-05 |
1992-11-02 |
Brigham Young University |
Support bonded polyalkylene-polyamine-poly(carboxylic acid) and extraction of metal ions therewith
|
RU2034853C1
(ru)
|
1992-07-14 |
1995-05-10 |
Научно-исследовательский институт строительных материалов при Томской государственной инженерно-строительной академии |
Способ получения полимерного сорбента для хроматографии
|
JP2871435B2
(ja)
|
1993-04-22 |
1999-03-17 |
イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー |
親水性ポリマー被覆パーフルオロカーボンポリマーベースのマトリックスの製造方法
|
JPH07110229A
(ja)
|
1993-10-12 |
1995-04-25 |
Nkk Corp |
金属ストリップループの最下点位置検出装置
|
US5478924A
(en)
|
1994-02-16 |
1995-12-26 |
Cramer; Steven M. |
Displacement chromatography of proteins using low molecular weight displacers
|
US5429746A
(en)
|
1994-02-22 |
1995-07-04 |
Smith Kline Beecham Corporation |
Antibody purification
|
US5856179A
(en)
|
1994-03-10 |
1999-01-05 |
Genentech, Inc. |
Polypeptide production in animal cell culture
|
US5423982A
(en)
|
1994-05-31 |
1995-06-13 |
Biosepra Inc. |
Liquid chromatography column adapted for in situ chemical sterilization
|
US5610285A
(en)
|
1994-08-24 |
1997-03-11 |
Bayer Corporation |
Purification of α-1 proteinase inhibitor using novel chromatographic separation conditions
|
US6359114B1
(en)
|
1995-06-07 |
2002-03-19 |
Aphton Corp. |
System for method for the modification and purification of proteins
|
US5691152A
(en)
|
1995-11-09 |
1997-11-25 |
E. R. Squibb & Sons, Inc. |
Stable avidin composition
|
AR005035A1
(es)
|
1995-12-11 |
1999-04-07 |
Merck Patent Ges Mit Beschränkter Haftung |
Procedimiento para preparar proteinas recombinantes en e. coli, mediante fermentacion con gran concentracion de celulas.
|
PT1864999E
(pt)
|
1996-11-27 |
2009-06-25 |
Genentech Inc |
Purificação por afinidade de um polipéptido numa matriz de proteína a
|
US5886154A
(en)
|
1997-06-20 |
1999-03-23 |
Lebing; Wytold R. |
Chromatographic method for high yield purification and viral inactivation of antibodies
|
US6955917B2
(en)
|
1997-06-20 |
2005-10-18 |
Bayer Healthcare Llc |
Chromatographic method for high yield purification and viral inactivation of antibodies
|
US6265542B1
(en)
|
1997-10-24 |
2001-07-24 |
Genentech, Inc. |
Purification of molecules
|
US7611831B2
(en)
|
1998-01-06 |
2009-11-03 |
Cerus Corporation |
Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
|
NZ507557A
(en)
|
1998-05-06 |
2003-10-31 |
Genentech Inc |
Protein purification by ion exchange chromatography
|
DE19858892A1
(de)
|
1998-12-19 |
2000-06-21 |
Merck Patent Gmbh |
Kontinuierliches Verfahren zur Trennung von Stoffen nach Molekülgröße
|
GB9902000D0
(en)
|
1999-01-30 |
1999-03-17 |
Delta Biotechnology Ltd |
Process
|
GB0028879D0
(en)
|
2000-11-27 |
2001-01-10 |
Prometic Biosciences Ltd |
Adsorbents and their use
|
HUP0303246A2
(hu)
|
2001-02-23 |
2003-12-29 |
Immunex Corporation |
Aktív fehérjék fokozott kinyerése
|
ITBO20010426A1
(it)
|
2001-07-06 |
2003-01-06 |
Alfa Wassermann Spa |
Processo per la purificazione di proteine farmacologicamente attive mediante cromatografia in scambio cationico
|
US7252799B2
(en)
|
2001-08-31 |
2007-08-07 |
Clearant, Inc. |
Methods for sterilizing preparations containing albumin
|
US20030095890A1
(en)
|
2001-09-24 |
2003-05-22 |
Shirley Miekka |
Methods for sterilizing biological materials containing non-aqueous solvents
|
WO2003045546A1
(en)
|
2001-11-27 |
2003-06-05 |
Prometic Biosciences Ltd. |
The use of metal-chelating adsorbents
|
US6660172B2
(en)
|
2002-01-31 |
2003-12-09 |
Koslow Technologies Corporation |
Precoat filtration media and methods of making and using
|
DK1472275T3
(da)
|
2002-02-05 |
2009-04-14 |
Genentech Inc |
Proteinoprensning
|
SI1501369T1
(sl)
|
2002-04-26 |
2015-10-30 |
Genentech, Inc. |
Neafinitetno čiščenje proteinov
|
US6902909B2
(en)
|
2002-07-09 |
2005-06-07 |
Synthecon, Inc. |
Methods for efficient production of mammalian recombinant proteins
|
EP2332996B1
(en)
|
2002-09-11 |
2014-10-15 |
Genentech, Inc. |
Purification of anti-Her2 antibodies
|
CA2498725C
(en)
|
2002-09-13 |
2014-07-08 |
Biogen Idec Inc. |
Method of purifying polypeptides by simulated moving bed chromatography
|
US7157276B2
(en)
|
2003-06-20 |
2007-01-02 |
Biogen Idec Inc. |
Use of depth filtration in series with continuous centrifugation to clarify mammalian cell cultures
|
EP1718675B2
(en)
|
2004-02-27 |
2017-01-25 |
Octapharma AG |
A method of providing a purified, virus safe antibody preparation
|
CA2552639C
(en)
|
2004-02-27 |
2012-05-01 |
Ge Healthcare Bio-Sciences Ab |
A process for the purification of antibodies
|
CN102492607B
(zh)
|
2004-06-04 |
2014-12-10 |
通用电气医疗集团生物科学公司 |
一次性生物反应器系统及方法
|
US20060004621A1
(en)
|
2004-06-30 |
2006-01-05 |
Malek Kamal M |
Real-time selection of survey candidates
|
WO2006026248A1
(en)
|
2004-08-25 |
2006-03-09 |
Sigma-Aldrich Co. |
Compositions and methods employing zwitterionic detergent combinations
|
EP2550971B1
(en)
|
2004-09-30 |
2016-11-09 |
Bayer HealthCare LLC |
Devices and Methods for Integrated Continuous Manufacturing of Biological Molecules
|
US20060153861A1
(en)
|
2004-09-30 |
2006-07-13 |
Scheinberg David A |
BCR-ABL imatinib resistance-associated peptides and methods of use thereof
|
BRPI0518207B1
(pt)
|
2004-10-21 |
2023-05-16 |
Cytiva Bioprocess R&D Ab |
Método de separação de um ou mais anticorpos de um ou mais outros compostos em uma amostra líquida
|
JP5553963B2
(ja)
|
2004-10-22 |
2014-07-23 |
アムジエン・インコーポレーテツド |
組換え抗体をリフォールディングする方法
|
WO2006073846A2
(en)
|
2004-12-22 |
2006-07-13 |
Ambrx, Inc. |
Methods for expression and purification of recombinant human growth hormone
|
CA2599650A1
(en)
|
2005-03-07 |
2006-09-14 |
Ge Healthcare Bio-Sciences Ab |
Method of sterilization
|
CN1923290A
(zh)
|
2005-04-29 |
2007-03-07 |
成都夸常医学工业有限公司 |
一种病毒灭活方法、其中所用的处理系统以及装置
|
WO2007055789A2
(en)
|
2005-10-31 |
2007-05-18 |
Neose Technologies, Inc. |
Expression of soluble therapeutic proteins
|
US7662930B2
(en)
|
2005-12-06 |
2010-02-16 |
Amgen Inc. |
Polishing steps used in multi-step protein purification processes
|
JP2009538116A
(ja)
|
2006-02-17 |
2009-11-05 |
ノバルティス アーゲー |
細菌抗原の精製
|
US7673757B2
(en)
|
2006-02-17 |
2010-03-09 |
Millipore Corporation |
Adsorbent filter media for removal of biological contaminants in process liquids
|
JP2010507068A
(ja)
|
2006-04-21 |
2010-03-04 |
バイエル・コーポレーシヨン |
原位置測定のための装置、システム、方法
|
WO2008036899A2
(en)
|
2006-09-22 |
2008-03-27 |
Amgen Inc. |
Methods for removing viral contaminants during protein purification
|
WO2008073620A2
(en)
|
2006-11-02 |
2008-06-19 |
Neose Technologies, Inc. |
Manufacturing process for the production of polypeptides expressed in insect cell-lines
|
KR101496477B1
(ko)
|
2007-02-01 |
2015-02-26 |
아반토르 퍼포먼스 머티리얼스, 인크. |
크로마토그래피 매질 및 크로마토그래피 장치 보관 용액 및 이들의 용도
|
US9597610B2
(en)
|
2007-03-09 |
2017-03-21 |
Ge Healthcare Bioprocess R&D Ab |
Packing system and method for chromatography columns
|
GB0704603D0
(en)
|
2007-03-09 |
2007-04-18 |
Ge Healthcare Bio Sciences Ab |
Packing system and method for chromatography columns
|
CN101678244B
(zh)
|
2007-04-17 |
2013-06-19 |
深度控股有限公司 |
用于连续膜吸附的方法和装置
|
US7901581B2
(en)
|
2007-06-15 |
2011-03-08 |
Ge Healthcare Bio-Sciences Ab |
Chromatography method
|
US7809258B2
(en)
|
2007-07-06 |
2010-10-05 |
Flir Systems Ab |
Camera and method for use with camera
|
US9109193B2
(en)
|
2007-07-30 |
2015-08-18 |
Ge Healthcare Bio-Sciences Corp. |
Continuous perfusion bioreactor system
|
ES2666170T3
(es)
|
2007-10-30 |
2018-05-03 |
Genentech, Inc. |
Purificación de anticuerpos mediante cromatografía de intercambio catiónico
|
CN104830813A
(zh)
|
2007-12-27 |
2015-08-12 |
大塚制药株式会社 |
与雌马酚合成有关的酶
|
UA100901C2
(ru)
*
|
2008-06-24 |
2013-02-11 |
Октафарма Аг |
Способ очищения фактора свертывания крови viii
|
TWI610936B
(zh)
|
2008-10-20 |
2018-01-11 |
艾伯維有限公司 |
使用蛋白質a親和性層析進行抗體之分離及純化
|
US9441028B2
(en)
*
|
2008-12-08 |
2016-09-13 |
Novo Nordisk A/S |
Counter current purification of polypeptides
|
EP2236617A1
(en)
|
2009-03-31 |
2010-10-06 |
Leukocare Ag |
Methods of terminal sterilization of biofunctional compositions
|
WO2010120514A2
(en)
|
2009-03-31 |
2010-10-21 |
The Trustees Of The University Of Pennsylvania |
Antigen-binding proteins comprising recombinant protein scaffolds
|
US8877060B2
(en)
|
2010-11-23 |
2014-11-04 |
Biovec Transfusion, Llc |
Methods for removing pathogens from a platelet preparation
|
US20120104380A1
(en)
|
2009-06-22 |
2012-05-03 |
Merck Patent Gmbh |
Conducting formulation
|
US8580554B2
(en)
|
2009-07-31 |
2013-11-12 |
Baxter International Inc. |
Method of producing a polypeptide or virus of interest in a continuous cell culture
|
CN102686245B
(zh)
|
2009-10-29 |
2015-09-30 |
阿森迪斯药物股份有限公司 |
可生物降解水凝胶的消毒
|
GB0922426D0
(en)
*
|
2009-12-22 |
2010-02-03 |
Ge Healthcare Bio Sciences Ab |
Containers for chromatography media
|
JP6023943B2
(ja)
*
|
2009-12-22 |
2016-11-09 |
ジーイー・ヘルスケア・バイオプロセス・アールアンドディ・アクチボラグ |
クロマトグラフィーカラムを乾式充填する方法
|
WO2011147762A2
(en)
|
2010-05-25 |
2011-12-01 |
Bayer Pharma Aktiengesellschaft |
Stabilized radiopharmaceutical composition
|
US9943781B2
(en)
|
2010-06-03 |
2018-04-17 |
Ge Healthcare Bioprocess R&D Ab |
Parallel assembly of chromatography column modules
|
WO2012049324A2
(en)
|
2010-10-15 |
2012-04-19 |
Straumann Holding Ag |
New emd formulation comprising pga
|
US20130032580A1
(en)
|
2010-11-29 |
2013-02-07 |
Mitsubishi Electric Corporation |
Optical path structure of laser processing machine
|
JP5802760B2
(ja)
|
2010-12-03 |
2015-11-04 |
ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ |
生体高分子クロマトグラフィーのためのシステム及びプロセス
|
KR102027596B1
(ko)
|
2010-12-06 |
2019-10-01 |
타폰 바이오시스템즈, 인코포레이티드 |
생물학적 산물을 위한 연속 처리 방법
|
CN102321316B
(zh)
|
2011-08-25 |
2013-04-24 |
上海恒方大高分子材料科技有限公司 |
一种适用于γ射线辐照消毒的医用PVC材料及其制备方法
|
RU2618219C2
(ru)
|
2011-09-30 |
2017-05-03 |
Байер Интеллектуэль Проперти Гмбх |
Гомогенное экструдированное изделие из термопластично перерабатываемых полиуретанов на основе полиэфирдиолов из янтарной кислоты и 1,3-пропандиола
|
EP2656892A1
(en)
*
|
2012-04-23 |
2013-10-30 |
Merck Patent GmbH |
Chromatography method
|
US20140154270A1
(en)
|
2012-05-21 |
2014-06-05 |
Chen Wang |
Purification of non-human antibodies using kosmotropic salt enhanced protein a affinity chromatography
|
EP2682168A1
(en)
|
2012-07-02 |
2014-01-08 |
Millipore Corporation |
Purification of biological molecules
|
ES2895173T3
(es)
|
2012-06-29 |
2022-02-17 |
Emd Millipore Corp |
Métodos para inactivar virus durante un proceso de purificación de proteínas
|
WO2014066471A1
(en)
|
2012-10-24 |
2014-05-01 |
Genzyme Corporation |
Elution of biomolecules from multi-modal resins using mes and mops as mobile phase modifiers
|
AU2014226126B2
(en)
|
2013-03-08 |
2019-02-14 |
Genzyme Corporation |
Continuous purification of therapeutic proteins
|
CN103223333B
(zh)
|
2013-04-15 |
2015-01-14 |
河海大学 |
一种含双偕胺肟基的改性硅胶吸附剂及其制备方法
|
JP6653654B2
(ja)
|
2014-01-17 |
2020-02-26 |
レプリゲン・コーポレイションRepligen Corporation |
クロマトグラフィーカラムの滅菌
|
TWI709569B
(zh)
|
2014-01-17 |
2020-11-11 |
美商健臻公司 |
無菌層析樹脂及其用於製造方法的用途
|
US20240100450A9
(en)
|
2014-01-17 |
2024-03-28 |
Repligen Corporation |
Sterilizing chromatography columns
|
TWI709570B
(zh)
*
|
2014-01-17 |
2020-11-11 |
美商健臻公司 |
無菌層析法及製法
|
CA3233933A1
(en)
|
2017-01-30 |
2018-08-02 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for reducing bioburden in chromatography
|
KR20210049155A
(ko)
|
2018-08-31 |
2021-05-04 |
젠자임 코포레이션 |
멸균 크로마토그래피 수지 및 제조 공정에서 이의 용도
|