HK1221214A1 - 二吡咯亞甲基的結晶及其製備方法 - Google Patents
二吡咯亞甲基的結晶及其製備方法Info
- Publication number
- HK1221214A1 HK1221214A1 HK16109149.3A HK16109149A HK1221214A1 HK 1221214 A1 HK1221214 A1 HK 1221214A1 HK 16109149 A HK16109149 A HK 16109149A HK 1221214 A1 HK1221214 A1 HK 1221214A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- dipyrromethene
- crystal
- manufacturing same
- manufacturing
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013081879 | 2013-04-10 | ||
| PCT/JP2014/060055 WO2014168103A1 (ja) | 2013-04-10 | 2014-04-07 | ピロール誘導体の結晶及びその製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1221214A1 true HK1221214A1 (zh) | 2017-05-26 |
Family
ID=51689511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16109149.3A HK1221214A1 (zh) | 2013-04-10 | 2016-08-01 | 二吡咯亞甲基的結晶及其製備方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9499483B2 (zh) |
| EP (2) | EP3190102B1 (zh) |
| JP (2) | JP6240164B2 (zh) |
| KR (2) | KR20210018557A (zh) |
| CN (2) | CN105164105B (zh) |
| BR (1) | BR112015025729B1 (zh) |
| CA (2) | CA2958625C (zh) |
| ES (2) | ES2661125T3 (zh) |
| HK (1) | HK1221214A1 (zh) |
| HU (2) | HUE038950T2 (zh) |
| IL (2) | IL241892B (zh) |
| TW (1) | TWI624447B (zh) |
| WO (1) | WO2014168103A1 (zh) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105473552B (zh) | 2013-08-27 | 2017-11-10 | 第一三共株式会社 | 用于产生吡咯衍生物及其中间体的方法 |
| CA3015964C (en) * | 2016-03-24 | 2021-08-03 | Daiichi Sankyo Company, Limited | Medicine for treating renal disease |
| TW202135802A (zh) * | 2019-12-25 | 2021-10-01 | 日商第一三共股份有限公司 | 包含吡咯羧醯胺之口腔崩散錠 |
| US20230029044A1 (en) * | 2020-02-21 | 2023-01-26 | Sumitomo Pharma Co., Ltd. | Optically resolved trolox intermediate and method for producing same |
| EP4317133A1 (en) * | 2021-03-30 | 2024-02-07 | Sunshine Lake Pharma Co., Ltd. | Crystalline form of pyrrole amide compound, preparation method therefor and use thereof |
| CA3216002A1 (en) * | 2021-04-26 | 2022-11-03 | Jiancheng Wang | Preparation method for pyrrole amide compound |
| CN113651745B (zh) * | 2021-09-09 | 2023-06-02 | 上海医药工业研究院 | 布瓦西坦中间体及其制备方法和纯化方法 |
| CN115784961A (zh) * | 2021-09-10 | 2023-03-14 | 上海鼎雅药物化学科技有限公司 | 埃沙西林酮及其中间体的合成方法 |
| WO2023134677A1 (zh) * | 2022-01-14 | 2023-07-20 | 广东东阳光药业有限公司 | 制备吡咯化合物的方法及其中间体 |
| CN114456098A (zh) * | 2022-01-19 | 2022-05-10 | 大连理工大学 | 糖尿病肾病药物艾莎利酮的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11279158A (ja) * | 1998-02-09 | 1999-10-12 | Pfizer Prod Inc | キナゾリン―４―オン誘導体の製造方法 |
| AU2930501A (en) * | 2000-01-07 | 2001-07-24 | Transform Pharmaceuticals, Inc. | High-throughput formation, identification, and analysis of diverse solid-forms |
| US6939968B2 (en) * | 2002-12-23 | 2005-09-06 | Bristol-Myers Squibb Company | Atropisomers of 3-substituted-4-arylquinolin-2-one derivatives |
| CN101006052B (zh) * | 2004-07-30 | 2013-11-06 | 埃克塞利希斯股份有限公司 | 作为药用制剂的吡咯衍生物 |
| PL1773768T3 (pl) | 2004-07-30 | 2019-03-29 | Exelixis, Inc. | Pochodne pirolu jako środki farmaceutyczne |
| KR100770434B1 (ko) | 2006-11-07 | 2007-10-26 | 여석준 | 다층 다단 다공성 플레이트에 의한 입자 분리·포집시스템 |
| WO2008126831A1 (ja) * | 2007-04-09 | 2008-10-23 | Daiichi Sankyo Company, Limited | ピロール誘導体のアトロプ異性体 |
| JP2010111657A (ja) * | 2008-10-07 | 2010-05-20 | Daiichi Sankyo Co Ltd | ピロール誘導体のアトロプ異性体を含有する医薬 |
| WO2010098286A1 (ja) * | 2009-02-25 | 2010-09-02 | 第一三共株式会社 | ミネラルコルチコイド受容体拮抗薬を含有する医薬 |
-
2014
- 2014-04-07 KR KR1020217004100A patent/KR20210018557A/ko not_active Application Discontinuation
- 2014-04-07 CN CN201480020522.6A patent/CN105164105B/zh active Active
- 2014-04-07 CA CA2958625A patent/CA2958625C/en active Active
- 2014-04-07 JP JP2015511244A patent/JP6240164B2/ja active Active
- 2014-04-07 KR KR1020157027888A patent/KR102234597B1/ko active IP Right Grant
- 2014-04-07 CA CA2908879A patent/CA2908879C/en active Active
- 2014-04-07 CN CN201710054565.1A patent/CN106916092B/zh active Active
- 2014-04-07 EP EP17157692.9A patent/EP3190102B1/en active Active
- 2014-04-07 ES ES14782674.7T patent/ES2661125T3/es active Active
- 2014-04-07 WO PCT/JP2014/060055 patent/WO2014168103A1/ja active Application Filing
- 2014-04-07 ES ES17157692T patent/ES2700962T3/es active Active
- 2014-04-07 HU HUE14782674A patent/HUE038950T2/hu unknown
- 2014-04-07 BR BR112015025729-1A patent/BR112015025729B1/pt active IP Right Grant
- 2014-04-07 HU HUE17157692A patent/HUE041725T2/hu unknown
- 2014-04-07 EP EP14782674.7A patent/EP2985277B1/en active Active
- 2014-04-09 TW TW103112941A patent/TWI624447B/zh active
-
2015
- 2015-10-06 IL IL241892A patent/IL241892B/en active IP Right Grant
- 2015-10-09 US US14/879,814 patent/US9499483B2/en active Active
-
2016
- 2016-08-01 HK HK16109149.3A patent/HK1221214A1/zh unknown
- 2016-11-15 US US15/352,407 patent/US9676713B2/en active Active
-
2017
- 2017-04-05 JP JP2017074865A patent/JP6511083B2/ja active Active
- 2017-04-28 US US15/582,064 patent/US9776961B2/en active Active
-
2018
- 2018-07-25 IL IL260782A patent/IL260782B/en active IP Right Grant
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