HK1219241A1 - 用於組織移植物去細胞化的方法 - Google Patents

用於組織移植物去細胞化的方法

Info

Publication number
HK1219241A1
HK1219241A1 HK16107324.4A HK16107324A HK1219241A1 HK 1219241 A1 HK1219241 A1 HK 1219241A1 HK 16107324 A HK16107324 A HK 16107324A HK 1219241 A1 HK1219241 A1 HK 1219241A1
Authority
HK
Hong Kong
Prior art keywords
decellularization
tissue grafts
grafts
tissue
Prior art date
Application number
HK16107324.4A
Other languages
English (en)
Inventor
‧繆爾
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida filed Critical Univ Florida
Publication of HK1219241A1 publication Critical patent/HK1219241A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3675—Nerve tissue, e.g. brain, spinal cord, nerves, dura mater
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
HK16107324.4A 2013-03-15 2016-06-23 用於組織移植物去細胞化的方法 HK1219241A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361794012P 2013-03-15 2013-03-15
PCT/US2014/030688 WO2014145854A1 (en) 2013-03-15 2014-03-17 Method for decellularization of tissue grafts

Publications (1)

Publication Number Publication Date
HK1219241A1 true HK1219241A1 (zh) 2017-03-31

Family

ID=51538115

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16107324.4A HK1219241A1 (zh) 2013-03-15 2016-06-23 用於組織移植物去細胞化的方法

Country Status (10)

Country Link
US (2) US9572911B2 (zh)
EP (2) EP2968673B1 (zh)
JP (1) JP6480911B2 (zh)
KR (2) KR102167247B1 (zh)
CN (1) CN105188787A (zh)
CL (1) CL2015002754A1 (zh)
DK (1) DK2968673T3 (zh)
ES (1) ES2881079T3 (zh)
HK (1) HK1219241A1 (zh)
WO (1) WO2014145854A1 (zh)

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US20150037436A1 (en) 2013-07-30 2015-02-05 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
US11513039B2 (en) 2015-05-28 2022-11-29 Axogen Corporation Nerve culture system
US11156595B2 (en) * 2015-05-28 2021-10-26 Axogen Corporation Organotypic DRG-peripheral nerve culture system
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US9955126B2 (en) * 2015-08-19 2018-04-24 Rapsodo Pte. Ltd. Systems and methods of analyzing moving objects
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
USD856517S1 (en) 2016-06-03 2019-08-13 Musculoskeletal Transplant Foundation Asymmetric tissue graft
US10945831B2 (en) 2016-06-03 2021-03-16 Musculoskeletal Transplant Foundation Asymmetric tissue graft
CN105920671B (zh) * 2016-06-22 2020-02-11 浙江元太生物科技有限公司 神经移植物的制备方法及其产品
KR101866249B1 (ko) * 2016-11-29 2018-06-12 박순현 생체 조직 투명화용 조성물 및 이를 이용한 생체 조직 투명화 방법
US20210113740A1 (en) * 2018-03-17 2021-04-22 Indian Institute Of Technology Hyderabad Decellularized corneal matrix based hydrogel, bioink formulation and methods thereof
US10813743B2 (en) 2018-09-07 2020-10-27 Musculoskeletal Transplant Foundation Soft tissue repair grafts and processes for preparing and using same
USD895812S1 (en) 2018-09-07 2020-09-08 Musculoskeletal Transplant Foundation Soft tissue repair graft
KR102406052B1 (ko) * 2018-11-15 2022-06-07 옥소젠 코포레이션 동물 기원 신경 이식편으로 신경을 수복하기 위한 재료 및 방법
AU2020291919A1 (en) 2019-06-11 2022-01-20 Axogen Corporation Wet preservation of tissue
JP2021027803A (ja) * 2019-08-09 2021-02-25 国立研究開発法人国立長寿医療研究センター 象牙質再生用細胞培養物
US20230041245A1 (en) * 2020-12-21 2023-02-09 L&C Bio Co., Ltd. Decellularized Nerve Graft and Method of Manufacturing the Same
WO2023122379A1 (en) 2021-12-22 2023-06-29 Axogen Corporation Tissue preservation solution, tissue preservation system, and methods of preserving tissue
WO2023122160A1 (en) 2021-12-22 2023-06-29 Axogen Corporation Nerve grafts containing regenerative compounds, methods of making the same, and methods of treatment using the same

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US3929678A (en) 1974-08-01 1975-12-30 Procter & Gamble Detergent composition having enhanced particulate soil removal performance
EP1315796B1 (en) * 2000-08-16 2006-07-12 Duke University Decellularized tissue engineered constructs and tissues
US7402319B2 (en) * 2002-09-27 2008-07-22 Board Of Regents, The University Of Texas System Cell-free tissue replacement for tissue engineering
CN100372511C (zh) * 2005-11-30 2008-03-05 烟台正海生物技术有限公司 一种脱细胞真皮基质
CN101095963A (zh) 2006-06-30 2008-01-02 中国人民解放军总医院 一种异体神经移植物、其制备方法及其应用
US8198245B2 (en) * 2007-07-27 2012-06-12 Humacyte, Inc. Compositions and methods for soft tissue augmentation
WO2010014021A1 (en) * 2008-07-30 2010-02-04 Mesynthes Limited Tissue scaffolds derived from forestomach extracellular matrix
KR101056069B1 (ko) 2008-10-13 2011-08-10 아주대학교산학협력단 동물조직 분말을 이용한 다공성 3차원 지지체의 제조방법
KR101822662B1 (ko) * 2009-02-04 2018-01-26 예일 유니버시티 폐 조직 엔지니어링
WO2012002986A2 (en) * 2009-12-21 2012-01-05 The Regents Of The University Of California Decellularized and delipidized extracellular matrix and methods of use
US8288472B2 (en) * 2009-12-29 2012-10-16 Chung-Yuan Christian University Antibiofouling nonionic-zwitterionic copolymer

Also Published As

Publication number Publication date
EP2968673A4 (en) 2016-11-02
JP6480911B2 (ja) 2019-03-13
KR20200119907A (ko) 2020-10-20
US9572911B2 (en) 2017-02-21
CN105188787A (zh) 2015-12-23
EP2968673A1 (en) 2016-01-20
US20170128624A1 (en) 2017-05-11
EP2968673B1 (en) 2021-06-02
DK2968673T3 (da) 2021-07-12
JP2016522000A (ja) 2016-07-28
CL2015002754A1 (es) 2016-02-05
US20160030636A1 (en) 2016-02-04
EP3928806A1 (en) 2021-12-29
KR102167247B1 (ko) 2020-10-19
WO2014145854A1 (en) 2014-09-18
ES2881079T3 (es) 2021-11-26
KR20150127247A (ko) 2015-11-16
KR102324450B1 (ko) 2021-11-10

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