HK1218576A1 - 結核病生物標誌物及其用途 - Google Patents

結核病生物標誌物及其用途

Info

Publication number
HK1218576A1
HK1218576A1 HK16106536.0A HK16106536A HK1218576A1 HK 1218576 A1 HK1218576 A1 HK 1218576A1 HK 16106536 A HK16106536 A HK 16106536A HK 1218576 A1 HK1218576 A1 HK 1218576A1
Authority
HK
Hong Kong
Prior art keywords
tuberculosis biomarkers
biomarkers
tuberculosis
Prior art date
Application number
HK16106536.0A
Other languages
English (en)
Inventor
Jacqueline Michele Achkar
Eustache Paramithiotis
Pascal Croteau
Original Assignee
Caprion Proteomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caprion Proteomics Inc filed Critical Caprion Proteomics Inc
Publication of HK1218576A1 publication Critical patent/HK1218576A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK16106536.0A 2013-02-28 2016-06-07 結核病生物標誌物及其用途 HK1218576A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361770432P 2013-02-28 2013-02-28
PCT/US2014/017289 WO2014133855A1 (en) 2013-02-28 2014-02-20 Tuberculosis biomarkers and uses thereof

Publications (1)

Publication Number Publication Date
HK1218576A1 true HK1218576A1 (zh) 2017-02-24

Family

ID=50236322

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16106536.0A HK1218576A1 (zh) 2013-02-28 2016-06-07 結核病生物標誌物及其用途

Country Status (8)

Country Link
US (2) US9857378B2 (zh)
EP (1) EP2962100B1 (zh)
JP (2) JP6416793B2 (zh)
AU (1) AU2014223824B2 (zh)
CA (2) CA2902068C (zh)
DK (1) DK2962100T3 (zh)
HK (1) HK1218576A1 (zh)
WO (1) WO2014133855A1 (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10613090B2 (en) 2014-05-09 2020-04-07 Ascendant Diagnostics, LLC Methods of detecting cancer
CN104808003B (zh) * 2015-04-30 2016-05-18 李继承 肺结核疗效评价试剂盒及其应用
CN105223364B (zh) * 2015-10-10 2018-02-23 广西医科大学 血清shbg蛋白作为肺结核病血清标志物及其应用
CN105588944B (zh) * 2016-02-25 2017-05-24 首都医科大学附属北京胸科医院 检测agp1、serpina3和cdh1含量的系统在筛查活动性结核病患者中的应用
EP3443356B1 (en) * 2016-04-15 2024-06-05 Stellenbosch University Host biomarkers for immunodiagnosis and monitoring of tuberculosis disease
EP3242132B1 (en) * 2016-05-05 2020-02-12 Ascendant Diagnostics, LLC Methods of detecting cancer
CN107367615A (zh) * 2016-05-11 2017-11-21 优势医疗有限责任公司 检测癌症的方法和试剂盒
WO2018013883A1 (en) 2016-07-14 2018-01-18 Caprion Proteomics Inc. Biomarkers of latent tuberculosis infection
US11680296B2 (en) * 2017-10-16 2023-06-20 Massachusetts Institute Of Technology Mycobacterium tuberculosis host-pathogen interaction
CN108504736A (zh) * 2018-04-09 2018-09-07 中国人民解放军第三0九医院 检测orm1基因表达量的系统在诊断结核病中的应用
US11592449B2 (en) * 2018-08-08 2023-02-28 Regeneron Pharmaceuticals, Inc. Use of LC-MS/MS to quantitate protein biomarkers
KR102127903B1 (ko) * 2019-01-29 2020-06-29 연세대학교 산학협력단 염증성 호흡기 질환의 진단용 바이오마커
CN110244048A (zh) * 2019-06-19 2019-09-17 中国人民解放军总医院第八医学中心 Serping1蛋白作为标志物在开发诊断活动性结核病的试剂中的应用
CN110275027B (zh) * 2019-07-03 2022-08-30 上海市肺科医院 一种用于辅助判断肺结核病理损伤和/或预后转归的生物学标志物
US20220326236A1 (en) * 2019-10-02 2022-10-13 Albert Einstein College Of Medicine Methods for assessing the risk of developing active tuberculosis
CN112684183B (zh) * 2020-12-20 2022-09-02 中国医学科学院病原生物学研究所 一种多抗原蛋白组合应用于肺结核的鉴别与诊断

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696561B1 (en) 1909-07-09 2004-02-24 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
US4475196A (en) 1981-03-06 1984-10-02 Zor Clair G Instrument for locating faults in aircraft passenger reading light and attendant call control system
US4447233A (en) 1981-04-10 1984-05-08 Parker-Hannifin Corporation Medication infusion pump
US4439196A (en) 1982-03-18 1984-03-27 Merck & Co., Inc. Osmotic drug delivery system
US4447224A (en) 1982-09-20 1984-05-08 Infusaid Corporation Variable flow implantable infusion apparatus
US4487603A (en) 1982-11-26 1984-12-11 Cordis Corporation Implantable microinfusion pump system
US4486194A (en) 1983-06-08 1984-12-04 James Ferrara Therapeutic device for administering medicaments through the skin
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
WO1990005144A1 (en) 1988-11-11 1990-05-17 Medical Research Council Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
US6291158B1 (en) 1989-05-16 2001-09-18 Scripps Research Institute Method for tapping the immunological repertoire
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US6172197B1 (en) 1991-07-10 2001-01-09 Medical Research Council Methods for producing members of specific binding pairs
US5840867A (en) 1991-02-21 1998-11-24 Gilead Sciences, Inc. Aptamer analogs specific for biomolecules
US5582981A (en) 1991-08-14 1996-12-10 Gilead Sciences, Inc. Method for identifying an oligonucleotide aptamer specific for a target
DE69233087T2 (de) 1991-11-22 2003-12-24 Affymetrix Inc N D Ges D Staat Verfahren zur Herstellung von Polymerarrays
PT1696031E (pt) 1991-12-02 2010-06-25 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
DK0616640T3 (da) 1991-12-02 2004-12-20 Medical Res Council Fremstilling af anti-selv antistoffer fra repertoirer af antistofsegmenter og fremvist på fag
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US6765087B1 (en) 1992-08-21 2004-07-20 Vrije Universiteit Brussel Immunoglobulins devoid of light chains
DK1087013T3 (da) 1992-08-21 2009-05-11 Univ Bruxelles Immunoglobuliner uden lette kæder
US5756291A (en) 1992-08-21 1998-05-26 Gilead Sciences, Inc. Aptamers specific for biomolecules and methods of making
US6838254B1 (en) 1993-04-29 2005-01-04 Conopco, Inc. Production of antibodies or (functionalized) fragments thereof derived from heavy chain immunoglobulins of camelidae
SE9400088D0 (sv) 1994-01-14 1994-01-14 Kabi Pharmacia Ab Bacterial receptor structures
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US5545531A (en) 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
US6111095A (en) 1995-06-07 2000-08-29 Merck & Co., Inc. Capped synthetic RNA, analogs, and aptamers
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
EP0880598A4 (en) 1996-01-23 2005-02-23 Affymetrix Inc RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
US5792613A (en) 1996-06-12 1998-08-11 The Curators Of The University Of Missouri Method for obtaining RNA aptamers based on shape selection
ATE332368T1 (de) 1997-01-21 2006-07-15 Gen Hospital Corp Selektion von proteinen mittels rns-protein fusionen
US6261804B1 (en) 1997-01-21 2001-07-17 The General Hospital Corporation Selection of proteins using RNA-protein fusions
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
GB9722131D0 (en) 1997-10-20 1997-12-17 Medical Res Council Method
EP1027456B1 (en) 1997-10-31 2005-03-16 Affymetrix, Inc. (a Delaware Corporation) Expression profiles in adult and fetal organs
US6261783B1 (en) 1997-12-15 2001-07-17 Gilead Sciences, Inc. Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
US6020135A (en) 1998-03-27 2000-02-01 Affymetrix, Inc. P53-regulated genes
US6458559B1 (en) 1998-04-22 2002-10-01 Cornell Research Foundation, Inc. Multivalent RNA aptamers and their expression in multicellular organisms
US6818418B1 (en) 1998-12-10 2004-11-16 Compound Therapeutics, Inc. Protein scaffolds for antibody mimics and other binding proteins
US7115396B2 (en) 1998-12-10 2006-10-03 Compound Therapeutics, Inc. Protein scaffolds for antibody mimics and other binding proteins
US7595383B1 (en) 1999-05-04 2009-09-29 University Of Medicine And Dentistry Of New Jersey Secreted proteins of Mycobacterium tuberculosis and their use as vaccines and diagnostic reagents
JP2003507065A (ja) * 1999-08-20 2003-02-25 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド Ｐｇｒｐ−ｌポリヌクレオチド、ポリペプチド、および抗体
WO2002020565A2 (en) 2000-09-08 2002-03-14 Universität Zürich Collections of repeat proteins comprising repeat modules
US20030133939A1 (en) 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US20030157561A1 (en) 2001-11-19 2003-08-21 Kolkman Joost A. Combinatorial libraries of monomer domains
JP4369662B2 (ja) 2001-04-26 2009-11-25 アビディア インコーポレイテッド 単量体ドメインのコンビナトリアルライブラリー
US20050089932A1 (en) 2001-04-26 2005-04-28 Avidia Research Institute Novel proteins with targeted binding
US20060223114A1 (en) 2001-04-26 2006-10-05 Avidia Research Institute Protein scaffolds and uses thereof
US20050048512A1 (en) 2001-04-26 2005-03-03 Avidia Research Institute Combinatorial libraries of monomer domains
US20040175756A1 (en) 2001-04-26 2004-09-09 Avidia Research Institute Methods for using combinatorial libraries of monomer domains
US20050053973A1 (en) 2001-04-26 2005-03-10 Avidia Research Institute Novel proteins with targeted binding
WO2004081026A2 (en) 2003-06-30 2004-09-23 Domantis Limited Polypeptides
DK1399484T3 (da) 2001-06-28 2010-11-08 Domantis Ltd Dobbelt-specifik ligand og anvendelse af denne
US6872541B2 (en) * 2001-07-25 2005-03-29 Coulter International Corp. Method and compositions for analysis of pentraxin receptors as indicators of disease
EP2366718A3 (en) 2002-06-28 2012-05-02 Domantis Limited Ligand
EP1578801A2 (en) 2002-12-27 2005-09-28 Domantis Limited Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand
WO2004101790A1 (en) 2003-05-14 2004-11-25 Domantis Limited A process for recovering polypeptides that unfold reversibly from a polypeptide repertoire
US20050164301A1 (en) 2003-10-24 2005-07-28 Avidia Research Institute LDL receptor class A and EGF domain monomers and multimers
US20060008844A1 (en) 2004-06-17 2006-01-12 Avidia Research Institute c-Met kinase binding proteins
GB0421639D0 (en) * 2004-09-29 2004-10-27 Proteome Sciences Plc Methods and compositions relating to alzheimer's disease
EP1824796A4 (en) 2004-11-16 2010-02-17 Avidia Res Inst PROTEIN SKELETONS AND USES THEREOF
CA2595682A1 (en) 2005-01-31 2006-08-03 Ablynx N.V. Method for generating variable domain sequences of heavy chain antibodies
GB0510511D0 (en) 2005-05-23 2005-06-29 St Georges Entpr Ltd Diagnosis of tuberculosis
CA2622441A1 (en) 2005-09-27 2007-04-05 Amunix, Inc. Proteinaceous pharmaceuticals and uses thereof
JP5525729B2 (ja) 2005-11-28 2014-06-18 ゲンマブ エー／エス 組換え一価抗体およびその作製方法
US10611818B2 (en) 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
EP2065707A1 (en) * 2007-11-28 2009-06-03 Laboratorios S.A.L.V.A.T., S.A. Detection of endometrial secretion markers for assesment of endometriosis
US20110129817A1 (en) 2009-11-30 2011-06-02 Baylor Research Institute Blood transcriptional signature of active versus latent mycobacterium tuberculosis infection
NZ590341A (en) * 2008-06-25 2012-07-27 Baylor Res Inst Blood transcriptional signature of mycobacterium tuberculosis infection
EP2310526A4 (en) * 2008-07-18 2011-11-02 Oragenics Inc COMPOSITIONS FOR THE DETECTION AND TREATMENT OF COLORECTAL CANCER
EP2536405A1 (en) * 2010-02-16 2012-12-26 Universita Degli Studi di Siena Non peptidic 14-3-3 inhibitors and the use thereof
JP2013524251A (ja) * 2010-04-13 2013-06-17 プロノタ エヌ．ヴェ． 妊娠高血圧疾患のバイオマーカー
RU2447445C1 (ru) * 2010-12-09 2012-04-10 Учреждение Российской академии медицинских наук Центральный научно-исследовательский институт туберкулеза РАМН Способ оценки эффективности лечения и динамики деструктивных изменений в легочной ткани при туберкулезе легких
EP2655662A2 (en) * 2010-12-23 2013-10-30 Centre Hospitalier Universitaire Vaudois Lausanne (CHUV) Methods for differentiating between disease states
EP2678448A4 (en) 2011-02-22 2014-10-01 Caris Life Sciences Luxembourg Holdings S A R L CIRCULATING BIOMARKERS
JP6776582B2 (ja) 2016-03-31 2020-10-28 Tdk株式会社 電子部品

Also Published As

Publication number Publication date
EP2962100B1 (en) 2021-07-28
US20180172699A1 (en) 2018-06-21
CA2902068A1 (en) 2014-09-04
JP6416793B2 (ja) 2018-10-31
DK2962100T3 (da) 2021-11-01
WO2014133855A8 (en) 2015-09-24
JP2019056707A (ja) 2019-04-11
EP2962100A1 (en) 2016-01-06
JP2016515199A (ja) 2016-05-26
CA2902068C (en) 2023-10-03
US20160154005A1 (en) 2016-06-02
US9857378B2 (en) 2018-01-02
WO2014133855A1 (en) 2014-09-04
AU2014223824A1 (en) 2015-09-10
AU2014223824B2 (en) 2020-02-27
CA3175634A1 (en) 2014-09-04

Similar Documents

Publication Publication Date Title
IL261743B (en) and their uses 33–il antibodies against
HK1218576A1 (zh) 結核病生物標誌物及其用途
HRP20181566T1 (hr) Biomarkeri raka i njihove uporabe
HK1218329A1 (zh) 型糖尿病生物標誌物及其用途
IL261547B (en) Antibodies against pesidine and their uses
IL245040A0 (en) Antibodies against pdgfr-beta and their uses
IL243974A0 (en) Antibodies against -prlr and uses
HK1205764A1 (zh) 結核病生物標誌物及其用途
SG10201708143QA (en) Anti-c10orf54 antibodies and uses thereof
HK1218314A1 (zh) 膿毒症生物標誌物及其應用
SG11201509116VA (en) Anti-tweakr antibodies and uses thereof
IL240248A0 (en) Met-binding substances and their uses
EP2819749A4 (en) BIOMARKERS ASSOCIATED WITH AUTISM AND USES THEREOF
GB201306147D0 (en) Novel biomarker signature and uses thereof
GB201211158D0 (en) Biomarkers and uses thereof
GB201307989D0 (en) Novel combinations and use
GB201320992D0 (en) Complex and uses thereof
ZA201601880B (en) Hetero-transglycosylase and uses thereof
GB201305297D0 (en) Novel agents and uses thereof
GB201308639D0 (en) Biomarkers and uses of thereof
GB201311696D0 (en) Assembly and methods
GB201301393D0 (en) Kiddibidet and pottibidet
GB201304166D0 (en) CelebQuiff and Instant Quiff
GB201218438D0 (en) Biomarkers and uses thereof