HK1205764A1 - 結核病生物標誌物及其用途 - Google Patents

結核病生物標誌物及其用途

Info

Publication number
HK1205764A1
HK1205764A1 HK15106261.2A HK15106261A HK1205764A1 HK 1205764 A1 HK1205764 A1 HK 1205764A1 HK 15106261 A HK15106261 A HK 15106261A HK 1205764 A1 HK1205764 A1 HK 1205764A1
Authority
HK
Hong Kong
Prior art keywords
tuberculosis biomarkers
biomarkers
tuberculosis
Prior art date
Application number
HK15106261.2A
Other languages
English (en)
Inventor
Urs Ochsner
David G Sterling
Nebojsa Janjic
Original Assignee
Somalogic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic Inc filed Critical Somalogic Inc
Publication of HK1205764A1 publication Critical patent/HK1205764A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK15106261.2A 2012-04-13 2015-07-01 結核病生物標誌物及其用途 HK1205764A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261623732P 2012-04-13 2012-04-13
PCT/US2013/036447 WO2013155460A1 (en) 2012-04-13 2013-04-12 Tuberculosis biomarkers and uses thereof

Publications (1)

Publication Number Publication Date
HK1205764A1 true HK1205764A1 (zh) 2015-12-24

Family

ID=49328218

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15106261.2A HK1205764A1 (zh) 2012-04-13 2015-07-01 結核病生物標誌物及其用途

Country Status (6)

Country Link
US (3) US20140155411A1 (zh)
EP (1) EP2836608A4 (zh)
JP (1) JP2015514227A (zh)
CA (1) CA2867481A1 (zh)
HK (1) HK1205764A1 (zh)
WO (1) WO2013155460A1 (zh)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140155411A1 (en) 2012-04-13 2014-06-05 Somalogic, Inc. Tuberculosis Biomarkers and Uses Thereof
WO2015164616A1 (en) * 2014-04-24 2015-10-29 Somalogic, Inc. Biomarkers for detection of tuberculosis
WO2016182967A1 (en) * 2015-05-08 2016-11-17 Somalogic, Inc. Biomarkers for detection of tuberculosis risk
GB201519872D0 (en) 2015-11-11 2015-12-23 Univ Cape Town And Ct For Infectious Disease Res Biomarkers for prospective determination of risk for development of active tuberculosis
GB201602305D0 (en) * 2016-02-09 2016-03-23 Medical Res Council And Imp Innovations Ltd TB Biomarkers
EP3443356B1 (en) * 2016-04-15 2024-06-05 Stellenbosch University Host biomarkers for immunodiagnosis and monitoring of tuberculosis disease
US10607228B1 (en) * 2016-08-24 2020-03-31 Jpmorgan Chase Bank, N.A. Dynamic rule strategy and fraud detection system and method
JP2019537443A (ja) * 2016-11-02 2019-12-26 バイオイズ カンパニー リミテッド 次世代配列決定法を用いた標的タンパク質の集団的定量方法とその用途
WO2018106481A1 (en) * 2016-12-09 2018-06-14 Basil Leaf Technologies, Llc Computer-implemented methods, systems, and computer-readable media for diagnosing a condition
JP6812789B2 (ja) * 2016-12-28 2021-01-13 富士通株式会社 情報処理装置、情報処理プログラム、および情報処理方法
WO2019202448A1 (en) * 2018-04-16 2019-10-24 University Of Cape Town A three-protein proteomic biomarker for prospective determination of risk for development of active tuberculosis
JPWO2020162441A1 (zh) * 2019-02-04 2020-08-13
BR112022006056A2 (pt) * 2019-09-30 2022-07-12 Univ Cape Town Método para diagnosticar tuberculose em amostras de urina
CN112034176B (zh) * 2020-07-09 2022-08-30 中国工程物理研究院材料研究所 Cntn1作为长期低剂量电离辐射暴露诊断的分子标记物的用途
US20220026417A1 (en) * 2020-07-21 2022-01-27 Industry-University Cooperation Foundation, Catholic University of Pusan Method of simultaneously diagnosing active tuberculosis and latent tuberculosis infection using human whole blood sample-derived biomarker
CN112481369A (zh) * 2020-12-03 2021-03-12 中国医学科学院病原生物学研究所 Msrb1作为结核病诊断分子标识的用途
US11676726B2 (en) * 2021-06-22 2023-06-13 David Haase Apparatus and method for generating a treatment plan for salutogenesis
WO2023021262A1 (en) * 2021-08-17 2023-02-23 Scotland's Rural College Methods of determining animal phenotypes
CN114250310B (zh) * 2021-11-15 2023-12-08 四川大学华西医院 用于检测结核病的dna甲基化标志物、诊断模型、甲基化探针及试剂盒
CN115466797A (zh) * 2022-06-06 2022-12-13 四川大学华西第二医院 用于检测rs4770965和rs9507713的试剂在制备结核筛查试剂盒中的用途
US20240229138A9 (en) * 2022-10-24 2024-07-11 Inflammatix, Inc. Fluidic device and methods for characterization of an infection or other condition

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US6143506A (en) * 1998-08-13 2000-11-07 The Research Foundation Of State Of Ny Diagnostic method for detection of periodontitis or peri-implantitis
WO2004001070A1 (en) * 2002-06-20 2003-12-31 Glaxo Group Limited Surrogate markers for the determination of the disease status of an individual infected by mycobacterium tuberculosis
US20060009378A1 (en) * 2002-11-14 2006-01-12 Itshak Golan Novel galectin sequences and compositions and methods utilizing same for treating or diagnosing arthritis and other chronic inflammatory diseases
DE602004026724D1 (de) * 2003-06-13 2010-06-02 Univ Pittsburgh Überwachung von immunologischen, hämatologischen und entzündlichen erkrankungen
GB0510511D0 (en) * 2005-05-23 2005-06-29 St Georges Entpr Ltd Diagnosis of tuberculosis
JP2007024631A (ja) 2005-07-14 2007-02-01 Human Science Shinko Zaidan 同位体標識法
WO2007039489A1 (en) * 2005-09-26 2007-04-12 Apotech Corporation Antibodies against april as biomarkers for early prognosis of lymphoma patients
US20070292869A1 (en) * 2006-03-02 2007-12-20 Ppd Biomarker Discovery Sciences, Llc Compositions and Methods for Analyzing Renal Cancer
US20080085524A1 (en) * 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
KR100961926B1 (ko) * 2007-08-30 2010-06-10 서울대학교산학협력단 당뇨병성 망막병증 검출용 바이오 마커 조성물 및 진단키트
AT505727B1 (de) * 2007-09-04 2009-06-15 Univ Innsbruck Verfahren zur diagnose des metabolischen syndroms
US20110129817A1 (en) * 2009-11-30 2011-06-02 Baylor Research Institute Blood transcriptional signature of active versus latent mycobacterium tuberculosis infection
TW201022492A (en) * 2008-06-25 2010-06-16 Baylor Res Inst Blood transcriptional signature of mycobacterium tuberculosis infection
ES2527455T3 (es) * 2009-05-14 2015-01-23 The Chancellor, Masters And Scholars Of The University Of Oxford Diagnóstico clínico de fibrosis/cirrosis hepática usando biomarcadores de proteínas plasmáticas humanas poco abundantes
BR112012024475A2 (pt) * 2010-03-31 2015-09-15 Firmenich & Cie preparação de cápsulas sólidas que contêm aromas.
US20110275794A1 (en) * 2010-04-12 2011-11-10 Somalogic, Inc. 5-position modified pyrimidines and their use
US20140155411A1 (en) 2012-04-13 2014-06-05 Somalogic, Inc. Tuberculosis Biomarkers and Uses Thereof
CN103065065A (zh) * 2012-11-18 2013-04-24 浙江大学 一种活动性肺结核蛋白表达差异质谱模型及构建方法

Also Published As

Publication number Publication date
CA2867481A1 (en) 2013-10-17
US20180128839A1 (en) 2018-05-10
US20160109462A1 (en) 2016-04-21
WO2013155460A1 (en) 2013-10-17
US10408847B2 (en) 2019-09-10
EP2836608A1 (en) 2015-02-18
JP2015514227A (ja) 2015-05-18
EP2836608A4 (en) 2016-02-24
US20140155411A1 (en) 2014-06-05

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