HK1217479A1 - -取代的氧- -二硝基-苯基 -氧-丙酸酯的化合物，方法及其應用 - Google Patents

-取代的氧- -二硝基-苯基 -氧-丙酸酯的化合物，方法及其應用

Info

Publication number
HK1217479A1
HK1217479A1 HK16105533.5A HK16105533A HK1217479A1 HK 1217479 A1 HK1217479 A1 HK 1217479A1 HK 16105533 A HK16105533 A HK 16105533A HK 1217479 A1 HK1217479 A1 HK 1217479A1
Authority
HK
Hong Kong
Prior art keywords
dinitro
oxo
phenyl
compounds
applications
Prior art date
Application number
HK16105533.5A
Other languages
English (en)
Inventor
加瓦拉 戈文達 拉朱盧
薩姆巴西瓦姆 加內甚
托馬斯 皮蒂亞帕拉姆皮爾 湯姆
錢德拉帕 科拉曼加拉 拉溫德拉
Original Assignee
Anthem Biosciences Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anthem Biosciences Pvt Ltd filed Critical Anthem Biosciences Pvt Ltd
Publication of HK1217479A1 publication Critical patent/HK1217479A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK16105533.5A 2013-06-06 2016-05-13 -取代的氧- -二硝基-苯基 -氧-丙酸酯的化合物，方法及其應用 HK1217479A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2466CH2013 2013-06-06
PCT/IB2014/061980 WO2014195896A1 (en) 2013-06-06 2014-06-05 Compounds of '3-(5-sustituted oxy-2,4-dinitro-phenyl)-2-oxo-propionic acid ester', process and applications thereof

Publications (1)

Publication Number Publication Date
HK1217479A1 true HK1217479A1 (zh) 2017-01-13

Family

ID=51022932

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16105533.5A HK1217479A1 (zh) 2013-06-06 2016-05-13 -取代的氧- -二硝基-苯基 -氧-丙酸酯的化合物，方法及其應用

Country Status (13)

Country Link
US (1) US9115128B2 (zh)
EP (1) EP3004047B1 (zh)
JP (1) JP6114881B2 (zh)
KR (1) KR101813214B1 (zh)
CN (1) CN105473544B (zh)
AU (1) AU2014276394B2 (zh)
BR (1) BR112015030527B1 (zh)
ES (1) ES2623295T3 (zh)
HK (1) HK1217479A1 (zh)
MX (1) MX2015016674A (zh)
NZ (1) NZ714747A (zh)
WO (1) WO2014195896A1 (zh)
ZA (1) ZA201508750B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106565522A (zh) * 2016-09-29 2017-04-19 福格森（武汉）生物科技股份有限公司 一种由氟代芳香化合物制备烷氧基芳香化合物的方法
CN107089982B (zh) 2017-05-11 2018-06-05 王靖林 4，5-二取代-1-氢-吡咯(2，3-f)喹啉-2，7，9-三羧酸酯化合物及应用
CN111087395A (zh) * 2019-12-31 2020-05-01 江西农业大学 一种四步法合成吡咯喹啉醌的制备方法
CN110981873A (zh) * 2019-12-31 2020-04-10 江西农业大学 一种五步法合成吡咯喹啉醌的制备方法
US20230139593A1 (en) * 2020-03-13 2023-05-04 The University Of Adelaide Treatment of disorders associated with oxidative stress and compounds for same
CN114890999B (zh) * 2022-05-27 2023-10-24 江苏信佑生物有限公司 一种pqq的制备方法
CN115894483A (zh) * 2022-11-11 2023-04-04 山东原力泰医药科技有限公司 制备吡咯喹啉醌的中间体及方法
CN118063459A (zh) * 2024-02-23 2024-05-24 福建康鸿生物科技有限公司 一种吡咯喹啉醌二钠盐晶体及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10512251A (ja) 1995-01-10 1998-11-24 スミスクライン・ビーチャム・ソシエタ・ペル・アチオニ 骨粗鬆症の治療に有用なインドール誘導体
US20070072894A1 (en) * 2005-03-24 2007-03-29 Kempf J V Synthesis of pyrroloquinoline quinone (PQQ)
CN101193888A (zh) * 2005-03-24 2008-06-04 Clf医疗技术加速程序有限公司 吡咯喹啉醌（pqq）的合成方法
CN101544567B (zh) * 2008-03-28 2012-07-25 中国科学院大连化学物理研究所 一步法合成二硝基甲苯的硝化方法
CN102432524A (zh) * 2011-11-18 2012-05-02 苏州诚和医药化学有限公司 一种制备2－羧酸吲哚的方法

Also Published As

Publication number Publication date
BR112015030527B1 (pt) 2020-12-01
KR101813214B1 (ko) 2017-12-29
EP3004047B1 (en) 2017-02-22
JP6114881B2 (ja) 2017-04-12
CN105473544A (zh) 2016-04-06
AU2014276394A1 (en) 2015-12-24
EP3004047A1 (en) 2016-04-13
JP2016521703A (ja) 2016-07-25
WO2014195896A1 (en) 2014-12-11
BR112015030527A2 (pt) 2017-07-25
US9115128B2 (en) 2015-08-25
ZA201508750B (en) 2017-11-29
US20140364613A1 (en) 2014-12-11
KR20160017061A (ko) 2016-02-15
NZ714747A (en) 2017-03-31
MX2015016674A (es) 2016-07-15
ES2623295T3 (es) 2017-07-10
CN105473544B (zh) 2017-10-31
AU2014276394B2 (en) 2018-10-04

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20220608