HK1217341A1 - 非溶血性 融合蛋白及其用途 - Google Patents

非溶血性 融合蛋白及其用途

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Publication number
HK1217341A1
HK1217341A1 HK16105309.7A HK16105309A HK1217341A1 HK 1217341 A1 HK1217341 A1 HK 1217341A1 HK 16105309 A HK16105309 A HK 16105309A HK 1217341 A1 HK1217341 A1 HK 1217341A1
Authority
HK
Hong Kong
Prior art keywords
llo
fusion proteins
hemolytic
hemolytic llo
llo fusion
Prior art date
Application number
HK16105309.7A
Other languages
English (en)
Inventor
Yvonne Paterson
Paulo Maciag
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of HK1217341A1 publication Critical patent/HK1217341A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
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    • A61K39/001116—Receptors for cytokines
    • A61K39/001119—Receptors for interleukins [IL]
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    • A61K39/001148—Regulators of development
    • A61K39/00115—Apoptosis related proteins, e.g. survivin or livin
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
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    • A61K2239/57—Skin; melanoma
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
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  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
HK16105309.7A 2008-06-23 2016-05-10 非溶血性 融合蛋白及其用途 HK1217341A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/213,696 US8771702B2 (en) 2001-03-26 2008-06-23 Non-hemolytic LLO fusion proteins and methods of utilizing same

Publications (1)

Publication Number Publication Date
HK1217341A1 true HK1217341A1 (zh) 2017-01-06

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ID=41550653

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Application Number Title Priority Date Filing Date
HK16105309.7A HK1217341A1 (zh) 2008-06-23 2016-05-10 非溶血性 融合蛋白及其用途

Country Status (10)

Country Link
US (3) US8771702B2 (zh)
EP (3) EP3530669A1 (zh)
JP (2) JP5597197B2 (zh)
DK (2) DK2942355T3 (zh)
ES (2) ES2719832T3 (zh)
HK (1) HK1217341A1 (zh)
HU (1) HUE042819T2 (zh)
PL (1) PL2942355T3 (zh)
PT (2) PT2307049T (zh)
WO (1) WO2010008782A1 (zh)

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US9499602B2 (en) 2016-11-22
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