HK1212207A1 - 經取代吡咯並嘧啶化合物、其組合物及其治療方法 - Google Patents

經取代吡咯並嘧啶化合物、其組合物及其治療方法

Info

Publication number
HK1212207A1
HK1212207A1 HK16100005.5A HK16100005A HK1212207A1 HK 1212207 A1 HK1212207 A1 HK 1212207A1 HK 16100005 A HK16100005 A HK 16100005A HK 1212207 A1 HK1212207 A1 HK 1212207A1
Authority
HK
Hong Kong
Prior art keywords
compositions
methods
treatment therewith
pyrrolopyrimidine compounds
substituted pyrrolopyrimidine
Prior art date
Application number
HK16100005.5A
Other languages
English (en)
Inventor
Andrew Antony Calabrese
Brandon David Jeffy
Dale Robinson
Dan Zhu
Dehua Huang
Jan Elsner
John Frederick Boylan
Lida Tehrani
Mark A Nagy
Raj Kumar Raheja
Paul Erdman
Rama K Narla
Roy L Harris
Tam Minh Tran
Jennifer R Riggs
Yuhong Ning
Shuichan Xu
Original Assignee
Signal Pharm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50031611&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1212207(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Signal Pharm Llc filed Critical Signal Pharm Llc
Publication of HK1212207A1 publication Critical patent/HK1212207A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK16100005.5A 2013-01-16 2016-01-04 經取代吡咯並嘧啶化合物、其組合物及其治療方法 HK1212207A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361753259P 2013-01-16 2013-01-16
PCT/US2014/011612 WO2014113429A2 (en) 2013-01-16 2014-01-15 Substituted pyrrolopyrimidine compounds, compositions thereof, and methods of treatment therewith

Publications (1)

Publication Number Publication Date
HK1212207A1 true HK1212207A1 (zh) 2016-06-10

Family

ID=50031611

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16100005.5A HK1212207A1 (zh) 2013-01-16 2016-01-04 經取代吡咯並嘧啶化合物、其組合物及其治療方法

Country Status (24)

Country Link
US (3) US9346812B2 (zh)
EP (2) EP3202403A1 (zh)
JP (1) JP2016505041A (zh)
KR (1) KR20150108389A (zh)
CN (1) CN105188704B (zh)
AR (1) AR094494A1 (zh)
AU (1) AU2014207641A1 (zh)
BR (1) BR112015016997A2 (zh)
CA (1) CA2897985A1 (zh)
CL (1) CL2015001990A1 (zh)
EA (1) EA201591327A1 (zh)
EC (1) ECSP15030799A (zh)
ES (1) ES2638179T3 (zh)
HK (1) HK1212207A1 (zh)
IL (1) IL239901A0 (zh)
MX (1) MX2015009209A (zh)
NI (1) NI201500094A (zh)
NZ (1) NZ630467A (zh)
PE (1) PE20151995A1 (zh)
PH (1) PH12015501576A1 (zh)
SG (1) SG11201505446WA (zh)
TW (1) TW201441227A (zh)
WO (1) WO2014113429A2 (zh)
ZA (1) ZA201505011B (zh)

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BR112018009252A2 (pt) 2015-11-06 2018-11-06 Samumed Llc tratamento da osteoartrite
CN105646496B (zh) * 2016-01-20 2018-07-20 华侨大学 一种7H-吡咯并[2,3-d]嘧啶衍生物、其合成方法及应用
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CN108727400B (zh) * 2017-05-24 2021-07-09 四川晶华生物科技有限公司 一种治疗肿瘤的化合物
EA202091003A1 (ru) * 2017-10-27 2020-09-11 Байер Акциенгезельшафт Новые производные пиразолопирролопиримидиндиона в качестве ингибиторов p2x3
CN112203659A (zh) * 2017-12-28 2021-01-08 财团法人生物技术开发中心 作为tyro3、axl和mertk(tam)家族受体酪氨酸激酶抑制剂的杂环化合物
KR102577242B1 (ko) 2017-12-28 2023-09-11 주식회사 대웅제약 카이네이즈 저해제로서의 아미노-메틸피페리딘 유도체
JP6995428B2 (ja) 2017-12-28 2022-01-14 デウン ファーマシューティカル カンパニー リミテッド キナーゼ阻害剤としてのオキシ－フルオロピペリジン誘導体
UA125551C2 (uk) * 2018-05-15 2022-04-13 Юніверсіті Оф Теннессі Рісерч Фаундейшн Спосіб лікування тричі негативного раку молочної залози або раку яєчника
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WO2022235054A1 (ko) * 2021-05-03 2022-11-10 주식회사 제이비케이랩 2,6-디클로로-4-(4-(4-하이드록시사이클로헥실아미노)-7h-피롤로[2,3-d]피리미딘-5-일)페놀을 유효성분으로 포함하는 암의 예방, 개선 또는 치료용 약학적 조성물

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US20160324861A1 (en) 2016-11-10
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