HK1211921A1 - Inhibitor compounds - Google Patents
Inhibitor compoundsInfo
- Publication number
- HK1211921A1 HK1211921A1 HK15112642.0A HK15112642A HK1211921A1 HK 1211921 A1 HK1211921 A1 HK 1211921A1 HK 15112642 A HK15112642 A HK 15112642A HK 1211921 A1 HK1211921 A1 HK 1211921A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- inhibitor compounds
- inhibitor
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1216017.2A GB201216017D0 (en) | 2012-09-07 | 2012-09-07 | Inhibitor compounds |
PCT/GB2013/052360 WO2014037750A1 (fr) | 2012-09-07 | 2013-09-09 | Composés inhibiteurs |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1211921A1 true HK1211921A1 (en) | 2016-06-03 |
Family
ID=47137117
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15112642.0A HK1211921A1 (en) | 2012-09-07 | 2015-12-23 | Inhibitor compounds |
Country Status (22)
Country | Link |
---|---|
US (6) | US9409907B2 (fr) |
EP (2) | EP2892889B1 (fr) |
JP (2) | JP6216791B2 (fr) |
CN (1) | CN104837829B (fr) |
AU (2) | AU2013311434B2 (fr) |
BR (1) | BR112015004489B1 (fr) |
CA (1) | CA2884006C (fr) |
CY (1) | CY1119714T1 (fr) |
DK (2) | DK2892889T3 (fr) |
ES (2) | ES2655194T3 (fr) |
GB (1) | GB201216017D0 (fr) |
HK (1) | HK1211921A1 (fr) |
HR (1) | HRP20171835T1 (fr) |
HU (1) | HUE036259T2 (fr) |
LT (1) | LT2892889T (fr) |
NO (1) | NO2892889T3 (fr) |
PL (1) | PL2892889T3 (fr) |
PT (1) | PT2892889T (fr) |
RS (1) | RS56750B1 (fr) |
RU (1) | RU2673079C2 (fr) |
SI (1) | SI2892889T1 (fr) |
WO (1) | WO2014037750A1 (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
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US9017724B2 (en) | 2004-02-24 | 2015-04-28 | The General Hospital Corporation | Catalytic radiofluorination |
CA2978149C (fr) | 2008-03-21 | 2019-02-12 | The General Hospital Corporation | Derives d'inositol destines a la detection et au traitement de la maladie d'alzheimer et de troubles connexes |
GB201104267D0 (en) | 2011-03-14 | 2011-04-27 | Cancer Rec Tech Ltd | Pyrrolopyridineamino derivatives |
GB201216018D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Pharmacologically active compounds |
GB201216017D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Inhibitor compounds |
RU2718876C2 (ru) * | 2013-08-23 | 2020-04-15 | Ньюфарма, Инк. | Некоторые химические соединения, композиции и способы |
GB201403536D0 (en) * | 2014-02-28 | 2014-04-16 | Cancer Rec Tech Ltd | Inhibitor compounds |
JP6616934B2 (ja) * | 2014-05-22 | 2019-12-04 | 株式会社 資生堂 | レナリドミドの光学分割方法 |
WO2016133935A1 (fr) * | 2015-02-17 | 2016-08-25 | Neupharma, Inc. | Entités chimiques, compositions et méthodes particulières |
CA2981844A1 (fr) | 2015-04-17 | 2016-10-20 | Netherlands Translational Research Center B.V. | Biomarqueurs pronostiques pour chimiotherapie basee sur un inhibiteur de ttk |
SG11201709837RA (en) * | 2015-05-29 | 2017-12-28 | Teijin Pharma Ltd | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF |
CN106366093B (zh) | 2015-07-21 | 2020-08-18 | 广州再极医药科技有限公司 | 稠环嘧啶类化合物、中间体、其制备方法、组合物和应用 |
GB201522532D0 (en) * | 2015-12-21 | 2016-02-03 | Cancer Rec Tech Ltd | Novel pyrrolo[3,2-c]pyridine-6-amino derivatives |
EP3497087B1 (fr) | 2016-08-15 | 2021-11-10 | Neupharma, Inc. | Dérivés de pyrrolo[1,2-c]pyrimidine, imidazol[1,5-c]pyrimidine, quinazoline, purine et imidazo[1,5-a][1,3,5]triazine en tant qu'inhibiteurs de la tyrosine kinase pour le traitement du cancer |
AR110238A1 (es) | 2016-11-28 | 2019-03-13 | Teijin Pharma Ltd | Derivado de pirido[3,4-d]pirimidina y su sal farmacéuticamente aceptable |
ES2905437T3 (es) | 2016-11-28 | 2022-04-08 | Teijin Pharma Ltd | Cristal de derivado de pirido[3,4-d]pirimidina o solvato del mismo |
EP3641745A1 (fr) * | 2017-06-20 | 2020-04-29 | The Institute of Cancer Research : The Royal Cancer Hospital | Méthodes et utilisations médicales |
GB201709840D0 (en) * | 2017-06-20 | 2017-08-02 | Inst Of Cancer Research: Royal Cancer Hospital | Methods and medical uses |
EP3701304B1 (fr) | 2017-10-26 | 2022-05-04 | CommScope Connectivity Belgium BVBA | Système de télécommunication |
GB201809460D0 (en) | 2018-06-08 | 2018-07-25 | Crt Pioneer Fund Lp | Salt form |
GB201809458D0 (en) | 2018-06-08 | 2018-07-25 | Crt Pioneer Fund Lp | Salt form |
CA3156777A1 (fr) | 2019-10-30 | 2021-05-06 | Fusheng ZHOU | Compose cyclique condense heterocyclique substitue, son procede de preparation et son utilisation pharmaceutique |
KR102396930B1 (ko) * | 2020-01-15 | 2022-05-12 | 한국과학기술연구원 | 피리도[3,4-d]피리미딘 유도체 및 이를 포함하는 치료용 약학 조성물 |
WO2022002118A1 (fr) * | 2020-07-01 | 2022-01-06 | 四川海思科制药有限公司 | Dérivé hétérocyclique à cycles fusionnés et son utilisation médicale |
BR112023009531A2 (pt) | 2020-11-18 | 2023-10-03 | Deciphera Pharmaceuticals Llc | Gcn2 e inibidores de perk quinase e métodos de uso dos mesmos |
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WO2002090360A1 (fr) | 2001-05-10 | 2002-11-14 | Smithkline Beecham Corporation | Composes utiles comme inhibiteurs de kinases pour le traitement de maladies hyperproliferatives |
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PL376751A1 (pl) | 2002-11-12 | 2006-01-09 | Abbott Laboratories | Bicykliczne podstawione aminy jako ligandy receptora histaminowego-3 |
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PT1899322E (pt) | 2005-06-28 | 2009-11-09 | Sanofi Aventis | Derivados de isoquinolina como inibidores de rho-cinase |
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GB0803018D0 (en) | 2008-02-19 | 2008-03-26 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
GB0812969D0 (en) | 2008-07-15 | 2008-08-20 | Sentinel Oncology Ltd | Pharmaceutical compounds |
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US9394290B2 (en) | 2010-10-21 | 2016-07-19 | Universitaet Des Saarlandes Campus Saarbruecken | Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases |
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GB201216017D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Inhibitor compounds |
GB201216018D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Pharmacologically active compounds |
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AU2014358850A1 (en) | 2013-12-06 | 2016-06-16 | F. Hoffmann-La Roche Ag | Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer |
GB201403536D0 (en) | 2014-02-28 | 2014-04-16 | Cancer Rec Tech Ltd | Inhibitor compounds |
KR20160132067A (ko) | 2014-03-11 | 2016-11-16 | 더 카운실 오브 더 퀸즐랜드 인스티튜트 오브 메디컬 리서치 | 암 공격성, 예후 및 치료에 대한 반응성의 결정 |
KR20170024120A (ko) | 2014-07-14 | 2017-03-06 | 시그날 파마소티칼 엘엘씨 | 치환된 피롤로피리미딘 화합물을 사용한 암의 치료방법, 이의 조성물 |
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GB201709840D0 (en) | 2017-06-20 | 2017-08-02 | Inst Of Cancer Research: Royal Cancer Hospital | Methods and medical uses |
EP3641745A1 (fr) | 2017-06-20 | 2020-04-29 | The Institute of Cancer Research : The Royal Cancer Hospital | Méthodes et utilisations médicales |
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2012
- 2012-09-07 GB GBGB1216017.2A patent/GB201216017D0/en not_active Ceased
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2013
- 2013-09-09 EP EP13760106.8A patent/EP2892889B1/fr active Active
- 2013-09-09 SI SI201330829T patent/SI2892889T1/sl unknown
- 2013-09-09 EP EP17192253.7A patent/EP3293183B1/fr active Active
- 2013-09-09 CN CN201380057967.7A patent/CN104837829B/zh active Active
- 2013-09-09 PT PT137601068T patent/PT2892889T/pt unknown
- 2013-09-09 WO PCT/GB2013/052360 patent/WO2014037750A1/fr active Application Filing
- 2013-09-09 CA CA2884006A patent/CA2884006C/fr active Active
- 2013-09-09 HU HUE13760106A patent/HUE036259T2/hu unknown
- 2013-09-09 ES ES13760106.8T patent/ES2655194T3/es active Active
- 2013-09-09 RU RU2015112580A patent/RU2673079C2/ru active
- 2013-09-09 NO NO13760106A patent/NO2892889T3/no unknown
- 2013-09-09 US US14/426,549 patent/US9409907B2/en active Active
- 2013-09-09 AU AU2013311434A patent/AU2013311434B2/en active Active
- 2013-09-09 DK DK13760106.8T patent/DK2892889T3/en active
- 2013-09-09 BR BR112015004489-1A patent/BR112015004489B1/pt active IP Right Grant
- 2013-09-09 JP JP2015530495A patent/JP6216791B2/ja active Active
- 2013-09-09 ES ES17192253T patent/ES2742442T3/es active Active
- 2013-09-09 RS RS20171314A patent/RS56750B1/sr unknown
- 2013-09-09 PL PL13760106T patent/PL2892889T3/pl unknown
- 2013-09-09 LT LTEP13760106.8T patent/LT2892889T/lt unknown
- 2013-09-09 DK DK17192253.7T patent/DK3293183T3/da active
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2015
- 2015-12-23 HK HK15112642.0A patent/HK1211921A1/xx unknown
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2016
- 2016-04-06 US US15/091,887 patent/US9890157B2/en active Active
- 2016-04-06 US US15/091,980 patent/US9834552B2/en active Active
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2017
- 2017-09-22 JP JP2017182377A patent/JP6496376B2/ja active Active
- 2017-11-24 HR HRP20171835TT patent/HRP20171835T1/hr unknown
- 2017-11-27 AU AU2017268488A patent/AU2017268488B2/en active Active
- 2017-12-29 CY CY20171101358T patent/CY1119714T1/el unknown
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2018
- 2018-01-08 US US15/864,499 patent/US10479788B2/en active Active
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2019
- 2019-10-10 US US16/598,717 patent/US11046688B2/en active Active
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2021
- 2021-05-13 US US17/319,231 patent/US11897877B2/en active Active
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