HK1210616A1 - 用於製備 激酶抑制劑的方法 - Google Patents
用於製備 激酶抑制劑的方法Info
- Publication number
- HK1210616A1 HK1210616A1 HK15111400.4A HK15111400A HK1210616A1 HK 1210616 A1 HK1210616 A1 HK 1210616A1 HK 15111400 A HK15111400 A HK 15111400A HK 1210616 A1 HK1210616 A1 HK 1210616A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- fms
- preparation
- kinase inhibitors
- fms kinase
- inhibitors
- Prior art date
Links
- 108010058398 Macrophage Colony-Stimulating Factor Receptor Proteins 0.000 title 2
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/18—Bridged systems
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- C—CHEMISTRY; METALLURGY
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- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- AIDS & HIV (AREA)
- Transplantation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261680446P | 2012-08-07 | 2012-08-07 | |
PCT/US2013/053602 WO2014025679A1 (en) | 2012-08-07 | 2013-08-05 | Process for the preparation of c-fms kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1210616A1 true HK1210616A1 (zh) | 2016-04-29 |
Family
ID=48980367
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15110017.1A HK1209418A1 (zh) | 2012-08-07 | 2015-10-14 | 用於製備 激酶抑制劑的方法 |
HK15111400.4A HK1210616A1 (zh) | 2012-08-07 | 2015-11-19 | 用於製備 激酶抑制劑的方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15110017.1A HK1209418A1 (zh) | 2012-08-07 | 2015-10-14 | 用於製備 激酶抑制劑的方法 |
Country Status (13)
Country | Link |
---|---|
US (2) | US9029352B2 (zh) |
EP (2) | EP2882744B8 (zh) |
JP (1) | JP6290884B2 (zh) |
CN (2) | CN107266405A (zh) |
AR (2) | AR092070A1 (zh) |
AU (2) | AU2013299926B2 (zh) |
ES (2) | ES2607807T3 (zh) |
HK (2) | HK1209418A1 (zh) |
IN (1) | IN2015DN00660A (zh) |
JO (2) | JOP20180012A1 (zh) |
TW (2) | TWI608004B (zh) |
UY (1) | UY34972A (zh) |
WO (1) | WO2014025679A1 (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI752980B (zh) | 2016-07-18 | 2022-01-21 | 比利時商健生藥品公司 | 4-氰基-n-(2-(4,4-二甲基環己-1-烯-1-基)-6-(2,2,6,6-四甲基四氫-2h-哌喃-4-基)吡啶-3-基)-1h-咪唑-2-甲醯胺之晶型 |
TW201811326A (zh) | 2016-07-18 | 2018-04-01 | 比利時商健生藥品公司 | 4-氰基-n-(2-(4,4-二甲基環己-1-烯-1-基)-6-(2,2,6,6-四甲基四氫-2h-哌喃-4-基)吡啶-3-基)-1h-咪唑-2-甲醯胺之鹽形式 |
JP6831558B2 (ja) * | 2016-08-23 | 2021-02-17 | 株式会社Hbcフナト | 脳機能改善組成物 |
EP3589324A1 (en) * | 2017-03-03 | 2020-01-08 | Janssen Biotech, Inc. | Co-therapy comprising a small molecule csf-1r inhibitor and an agonistic antibody that specifically binds cd40 for the treatment of cancer |
WO2020222109A1 (en) | 2019-05-02 | 2020-11-05 | Janssen Biotech, Inc. | Csf-1/csf-1r gene set |
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- 2013-08-06 TW TW102128026A patent/TWI608004B/zh active
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TW201741292A (zh) | 2017-12-01 |
WO2014025679A1 (en) | 2014-02-13 |
JP6290884B2 (ja) | 2018-03-07 |
EP2882744A1 (en) | 2015-06-17 |
AU2013299926A1 (en) | 2015-05-21 |
AU2013299926B2 (en) | 2017-06-01 |
TW201408664A (zh) | 2014-03-01 |
AU2017201415C1 (en) | 2019-05-23 |
EP3091006B1 (en) | 2018-01-17 |
CN104520295A (zh) | 2015-04-15 |
AU2017201415A1 (en) | 2017-03-16 |
US9029352B2 (en) | 2015-05-12 |
UY34972A (es) | 2014-02-28 |
AR092070A1 (es) | 2015-03-18 |
ES2607807T3 (es) | 2017-04-04 |
CN104520295B (zh) | 2017-07-18 |
IN2015DN00660A (zh) | 2015-06-26 |
HK1209418A1 (zh) | 2016-04-01 |
US20150232439A1 (en) | 2015-08-20 |
TWI608004B (zh) | 2017-12-11 |
EP2882744B8 (en) | 2016-11-09 |
TWI646090B (zh) | 2019-01-01 |
JOP20180012A1 (ar) | 2019-01-30 |
AU2017201415B2 (en) | 2019-01-03 |
EP2882744B1 (en) | 2016-09-21 |
ES2658773T3 (es) | 2018-03-12 |
EP3091006A1 (en) | 2016-11-09 |
JP2015524471A (ja) | 2015-08-24 |
CN107266405A (zh) | 2017-10-20 |
AR117002A2 (es) | 2021-06-30 |
JO3248B1 (ar) | 2018-09-16 |
US20140045789A1 (en) | 2014-02-13 |
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