HK1208220A1 - Synthesis method of 9-allylcamptothecin derivatives 9- - Google Patents
Synthesis method of 9-allylcamptothecin derivatives 9-Info
- Publication number
- HK1208220A1 HK1208220A1 HK15108829.3A HK15108829A HK1208220A1 HK 1208220 A1 HK1208220 A1 HK 1208220A1 HK 15108829 A HK15108829 A HK 15108829A HK 1208220 A1 HK1208220 A1 HK 1208220A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- allylcamptothecin
- derivatives
- synthesis method
- synthesis
- allylcamptothecin derivatives
- Prior art date
Links
- 238000001308 synthesis method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/1616—Coordination complexes, e.g. organometallic complexes, immobilised on an inorganic support, e.g. ship-in-a-bottle type catalysts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410018451.8A CN104774209B (zh) | 2014-01-15 | 2014-01-15 | 一种9-烯丙基喜树碱衍生物的合成方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1208220A1 true HK1208220A1 (en) | 2016-02-26 |
Family
ID=53542388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15108829.3A HK1208220A1 (en) | 2014-01-15 | 2015-09-10 | Synthesis method of 9-allylcamptothecin derivatives 9- |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9643975B2 (ja) |
| EP (1) | EP3095785B1 (ja) |
| JP (1) | JP6216895B2 (ja) |
| KR (1) | KR101887447B1 (ja) |
| CN (1) | CN104774209B (ja) |
| AU (1) | AU2014378009B2 (ja) |
| BR (1) | BR112016016361A2 (ja) |
| CA (1) | CA2935504C (ja) |
| HK (1) | HK1208220A1 (ja) |
| MX (1) | MX365384B (ja) |
| RU (1) | RU2658017C2 (ja) |
| SG (1) | SG11201605485QA (ja) |
| WO (1) | WO2015106633A1 (ja) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6185319A (ja) * | 1984-10-03 | 1986-04-30 | Yakult Honsha Co Ltd | 抗腫瘍剤 |
| GB9510716D0 (en) * | 1995-05-26 | 1995-07-19 | Pharmacia Spa | Substituted camptothecin derivatives and process for their preparation |
| IT1282673B1 (it) * | 1996-02-23 | 1998-03-31 | Ist Naz Stud Cura Dei Tumori | Derivati della camptotecina e loro uso come agenti antitumorali |
| CN100406460C (zh) * | 2003-11-10 | 2008-07-30 | 中国科学院上海药物研究所 | 喜树碱的新衍生物、制备方法和用途 |
| CN1587265A (zh) * | 2004-07-08 | 2005-03-02 | 浙江大学 | 10－烷氧基喜树碱衍生物及其制备方法与应用 |
| CN101033230B (zh) * | 2006-03-10 | 2010-12-08 | 中国科学院上海药物研究所 | 一类喜树碱衍生物及其应用 |
| CN101337966B (zh) * | 2007-07-06 | 2011-05-18 | 江苏恒瑞医药股份有限公司 | 一种制备高纯度伊立替康的方法 |
| CN102046634B (zh) * | 2008-05-29 | 2013-04-24 | 日本迈科洛生物制药有限公司 | 喜树碱衍生物的制备方法 |
| CN101880285B (zh) * | 2010-06-24 | 2012-07-04 | 华东师范大学 | 一种烯丙基取代喜树碱化合物的合成方法 |
| TWI417248B (zh) | 2011-12-23 | 2013-12-01 | Ind Tech Res Inst | 熱電材料與其製造方法、以及包含其熱電模組 |
| CN102627653B (zh) * | 2012-03-20 | 2014-10-29 | 南京臣功制药股份有限公司 | 盐酸伊立替康的制备方法 |
| WO2013179144A2 (en) * | 2012-06-01 | 2013-12-05 | Oxalys Pharmaceuticals | Chemical suppressors of neurotoxicity in synucleinopathic diseases |
-
2014
- 2014-01-15 CN CN201410018451.8A patent/CN104774209B/zh active Active
- 2014-12-31 MX MX2016009179A patent/MX365384B/es active IP Right Grant
- 2014-12-31 JP JP2016564366A patent/JP6216895B2/ja not_active Expired - Fee Related
- 2014-12-31 BR BR112016016361A patent/BR112016016361A2/pt not_active Application Discontinuation
- 2014-12-31 KR KR1020167022281A patent/KR101887447B1/ko active IP Right Grant
- 2014-12-31 CA CA2935504A patent/CA2935504C/en active Active
- 2014-12-31 WO PCT/CN2014/096002 patent/WO2015106633A1/zh active Application Filing
- 2014-12-31 RU RU2016133470A patent/RU2658017C2/ru active
- 2014-12-31 EP EP14878733.6A patent/EP3095785B1/en not_active Not-in-force
- 2014-12-31 US US15/111,452 patent/US9643975B2/en active Active
- 2014-12-31 SG SG11201605485QA patent/SG11201605485QA/en unknown
- 2014-12-31 AU AU2014378009A patent/AU2014378009B2/en not_active Ceased
-
2015
- 2015-09-10 HK HK15108829.3A patent/HK1208220A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP3095785A4 (en) | 2016-11-23 |
| US20160340364A1 (en) | 2016-11-24 |
| JP6216895B2 (ja) | 2017-10-18 |
| BR112016016361A2 (pt) | 2017-08-08 |
| MX2016009179A (es) | 2016-09-09 |
| MX365384B (es) | 2019-05-31 |
| RU2658017C2 (ru) | 2018-06-19 |
| EP3095785B1 (en) | 2018-02-07 |
| CN104774209B (zh) | 2018-06-19 |
| AU2014378009B2 (en) | 2017-09-07 |
| WO2015106633A1 (zh) | 2015-07-23 |
| KR101887447B1 (ko) | 2018-08-10 |
| CA2935504C (en) | 2018-10-23 |
| AU2014378009A1 (en) | 2016-07-21 |
| EP3095785A1 (en) | 2016-11-23 |
| US9643975B2 (en) | 2017-05-09 |
| JP2017507170A (ja) | 2017-03-16 |
| KR20160144962A (ko) | 2016-12-19 |
| CN104774209A (zh) | 2015-07-15 |
| RU2016133470A (ru) | 2018-02-20 |
| SG11201605485QA (en) | 2016-08-30 |
| CA2935504A1 (en) | 2015-07-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230118 |