HK1207885A1 - Differentiation of human embryonic stem cells into pancreatic endoderm - Google Patents

Differentiation of human embryonic stem cells into pancreatic endoderm Download PDF

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Publication number
HK1207885A1
HK1207885A1 HK15108511.6A HK15108511A HK1207885A1 HK 1207885 A1 HK1207885 A1 HK 1207885A1 HK 15108511 A HK15108511 A HK 15108511A HK 1207885 A1 HK1207885 A1 HK 1207885A1
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HK
Hong Kong
Prior art keywords
differentiation
stem cells
pancreatic endoderm
embryonic stem
human embryonic
Prior art date
Application number
HK15108511.6A
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English (en)
Chinese (zh)
Inventor
Alireza Rezania
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Janssen Biotech, Inc.
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Publication date
Application filed by Janssen Biotech, Inc. filed Critical Janssen Biotech, Inc.
Publication of HK1207885A1 publication Critical patent/HK1207885A1/xx

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/005—Protein-free medium
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/065—Modulators of histone acetylation
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/19—Growth and differentiation factors [GDF]
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK15108511.6A 2012-05-07 2013-05-07 Differentiation of human embryonic stem cells into pancreatic endoderm HK1207885A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261643684P 2012-05-07 2012-05-07
US201261643684P 2012-05-07
PCT/US2013/039940 WO2013169769A1 (en) 2012-05-07 2013-05-07 Differentiation of human embryonic stem cells into pancreatic endoderm

Publications (1)

Publication Number Publication Date
HK1207885A1 true HK1207885A1 (en) 2016-02-12

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Application Number Title Priority Date Filing Date
HK15108511.6A HK1207885A1 (en) 2012-05-07 2013-05-07 Differentiation of human embryonic stem cells into pancreatic endoderm

Country Status (17)

Country Link
US (1) US20140162359A1 (enExample)
EP (1) EP2847319A4 (enExample)
JP (1) JP6450674B2 (enExample)
KR (1) KR20150014478A (enExample)
CN (1) CN104284977A (enExample)
AR (1) AR090970A1 (enExample)
AU (1) AU2013259706A1 (enExample)
BR (1) BR112014027783A2 (enExample)
CA (1) CA2872770A1 (enExample)
HK (1) HK1207885A1 (enExample)
IL (1) IL235132A0 (enExample)
IN (1) IN2014DN08561A (enExample)
MX (1) MX2014013524A (enExample)
PH (1) PH12014502686A1 (enExample)
RU (1) RU2668814C2 (enExample)
SG (1) SG11201406884SA (enExample)
WO (1) WO2013169769A1 (enExample)

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EP3008170A4 (en) 2013-06-11 2016-11-09 Harvard College SC-CELLS AND COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF
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CN107614678B (zh) 2014-12-18 2021-04-30 哈佛学院校长同事会 干细胞来源的β细胞的产生方法及其使用方法
US10443042B2 (en) 2014-12-18 2019-10-15 President And Fellows Of Harvard College Serum-free in vitro directed differentiation protocol for generating stem cell-derived beta cells and uses thereof
CN106467918B (zh) * 2015-08-18 2020-07-31 中国科学技术大学先进技术研究院 一种基于人皮肤细胞的胰岛素分泌细胞的诱导方法及应用
CN111094547B (zh) * 2017-06-14 2024-02-09 德国亥姆霍兹慕尼黑中心健康与环境研究中心（有限公司） 用于纯化源自人胚胎干细胞的内胚层和胰腺内胚层细胞的方法
CA3081762A1 (en) 2017-11-15 2019-05-23 Semma Therapeutics, Inc. Islet cell manufacturing compositions and methods of use
CA3108275A1 (en) 2018-08-10 2020-02-13 Vertex Pharmaceuticals Incorporated Stem cell derived islet differentiation
US12378572B2 (en) 2018-09-07 2025-08-05 Crispr Therapeutics Ag Universal donor cells
AU2020283150B2 (en) 2019-05-31 2023-08-17 Viacyte, Inc. Cell encapsulation devices with controlled oxygen diffusion distances
AU2020283056B2 (en) 2019-05-31 2023-06-08 Viacyte, Inc. A biocompatible membrane composite
US20220234006A1 (en) 2019-05-31 2022-07-28 W. L. Gore & Associates, Inc. A biocompatible membrane composite
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EP4025690A1 (en) 2019-09-05 2022-07-13 CRISPR Therapeutics AG Universal donor cells
BR112022004031A2 (pt) 2019-09-05 2022-08-16 Crispr Therapeutics Ag Células doadoras universais
US11578309B2 (en) 2020-12-31 2023-02-14 Crispr Therapeutics Ag Universal donor cells
CN113046306B (zh) * 2021-03-12 2022-10-18 广东东阳光药业有限公司 一种多能干细胞的培养方法

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Also Published As

Publication number Publication date
RU2668814C2 (ru) 2018-10-02
IN2014DN08561A (enExample) 2015-05-22
WO2013169769A1 (en) 2013-11-14
MX2014013524A (es) 2015-02-10
AU2013259706A1 (en) 2014-10-30
KR20150014478A (ko) 2015-02-06
AR090970A1 (es) 2014-12-17
BR112014027783A2 (pt) 2017-06-27
EP2847319A4 (en) 2015-12-16
CN104284977A (zh) 2015-01-14
JP2015516161A (ja) 2015-06-11
PH12014502686A1 (en) 2015-01-26
RU2014149185A (ru) 2016-06-27
IL235132A0 (en) 2014-12-31
SG11201406884SA (en) 2014-11-27
EP2847319A1 (en) 2015-03-18
US20140162359A1 (en) 2014-06-12
CA2872770A1 (en) 2013-11-14
JP6450674B2 (ja) 2019-01-09

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