HK1207684A1 - 線粒體毒性試驗 - Google Patents

線粒體毒性試驗

Info

Publication number
HK1207684A1
HK1207684A1 HK15108295.8A HK15108295A HK1207684A1 HK 1207684 A1 HK1207684 A1 HK 1207684A1 HK 15108295 A HK15108295 A HK 15108295A HK 1207684 A1 HK1207684 A1 HK 1207684A1
Authority
HK
Hong Kong
Prior art keywords
toxicity test
mitochondrial toxicity
mitochondrial
test
toxicity
Prior art date
Application number
HK15108295.8A
Other languages
English (en)
Inventor
Fredrik Sjvall
Johannes Ehinger
Magnus Hansson
Eskil Elmer
Derek Gregory Batcheller
Original Assignee
Neurovive Pharmaceutical Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurovive Pharmaceutical Ab filed Critical Neurovive Pharmaceutical Ab
Publication of HK1207684A1 publication Critical patent/HK1207684A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5076—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
    • G01N33/5079—Mitochondria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15108295.8A 2012-10-05 2015-08-26 線粒體毒性試驗 HK1207684A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201270609 2012-10-05
PCT/EP2013/070666 WO2014053617A1 (en) 2012-10-05 2013-10-04 Mitochondrial toxicity test

Publications (1)

Publication Number Publication Date
HK1207684A1 true HK1207684A1 (zh) 2016-02-05

Family

ID=47137411

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15108295.8A HK1207684A1 (zh) 2012-10-05 2015-08-26 線粒體毒性試驗

Country Status (19)

Country Link
US (1) US20150253306A1 (zh)
EP (1) EP2904391B1 (zh)
JP (1) JP6300806B2 (zh)
KR (1) KR20150063557A (zh)
CN (1) CN104704361B (zh)
AU (1) AU2013326508A1 (zh)
BR (1) BR112015007290A2 (zh)
CA (1) CA2886921A1 (zh)
CL (1) CL2015000789A1 (zh)
EA (1) EA201590686A1 (zh)
ES (1) ES2665522T3 (zh)
HK (1) HK1207684A1 (zh)
IL (1) IL237759B (zh)
MX (1) MX2015003980A (zh)
NZ (1) NZ630856A (zh)
PH (1) PH12015500519B1 (zh)
SG (1) SG11201501345XA (zh)
TW (1) TWI616533B (zh)
WO (1) WO2014053617A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104297442B (zh) * 2014-11-03 2016-08-17 天津中医药大学 内源性小分子物质在快速检测早期心脏毒性方面的应用
JP7109190B2 (ja) 2015-03-27 2022-07-29 アジレント・テクノロジーズ・インク 生細胞の統合された代謝ベースラインおよび代謝能を決定するための方法およびシステム
US20210375467A1 (en) * 2018-06-26 2021-12-02 Ribonova Inc. Systems and Methods for Computing Measurements for Mitochondrial Diseases
JP7030667B2 (ja) 2018-09-28 2022-03-07 株式会社東芝 電力系統事故原因推定装置、電力系統事故原因推定システム、電力系統事故原因推定用コンピュータプログラムおよび電力系統事故原因推定方法
WO2020236580A1 (en) * 2019-05-17 2020-11-26 The Regents Of The University Of California Mitochondrial respirometry in frozen specimens
CN111024937A (zh) * 2019-11-20 2020-04-17 辉源生物科技（上海）有限公司 检测对肝脏线粒体功能存在影响的候选药物的方法
CN111579763B (zh) * 2020-04-09 2023-04-07 北京博瑞世安科技有限公司 检测白细胞线粒体呼吸功能的方法及检测肾阴虚症的方法
CN111607632A (zh) * 2020-05-29 2020-09-01 中国人民解放军陆军第八十二集团军医院 一种肌肉组织的线粒体呼吸功能原位测定方法
KR102273163B1 (ko) * 2020-09-10 2021-07-05 주식회사 파이안바이오테크놀로지 혈소판 유래 미토콘드리아의 수득 방법 및 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2186636A1 (en) * 1994-03-30 1995-10-12 Corinna Herrnstadt Diagnosis, therapy and cellular and animal models for diseases associated with mitochondrial defects
CN1230531C (zh) * 2002-12-09 2005-12-07 清华大学 从样品中分离细胞粒子的方法
US10920260B2 (en) * 2008-08-15 2021-02-16 Erasmus University Medical Center Rotterdam Methods and devices for assessment of mitochondrial function
WO2011150221A2 (en) * 2010-05-26 2011-12-01 Knopp Neurosciences, Inc. Compounds and methods of modulating mitochondrial bioenergetic efficiency through an interaction with atp synthase (complex v) and its subunits
US9581600B2 (en) * 2010-12-09 2017-02-28 André Arsenault In vitro mitochondrial function test (MFT) and uses thereof

Also Published As

Publication number Publication date
TW201428106A (zh) 2014-07-16
CA2886921A1 (en) 2014-04-10
MX2015003980A (es) 2015-07-06
NZ630856A (en) 2016-08-26
BR112015007290A2 (pt) 2017-07-04
IL237759B (en) 2018-06-28
PH12015500519A1 (en) 2015-04-27
TWI616533B (zh) 2018-03-01
US20150253306A1 (en) 2015-09-10
CN104704361B (zh) 2018-01-16
CN104704361A (zh) 2015-06-10
JP6300806B2 (ja) 2018-03-28
KR20150063557A (ko) 2015-06-09
SG11201501345XA (en) 2015-03-30
CL2015000789A1 (es) 2015-07-10
ES2665522T3 (es) 2018-04-26
WO2014053617A1 (en) 2014-04-10
AU2013326508A1 (en) 2015-03-19
EP2904391A1 (en) 2015-08-12
JP2015535690A (ja) 2015-12-17
EP2904391B1 (en) 2018-01-17
EA201590686A1 (ru) 2015-07-30
PH12015500519B1 (en) 2015-04-27

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