SG11201501345XA - Mitochondrial toxicity test - Google Patents

Mitochondrial toxicity test

Info

Publication number
SG11201501345XA
SG11201501345XA SG11201501345XA SG11201501345XA SG11201501345XA SG 11201501345X A SG11201501345X A SG 11201501345XA SG 11201501345X A SG11201501345X A SG 11201501345XA SG 11201501345X A SG11201501345X A SG 11201501345XA SG 11201501345X A SG11201501345X A SG 11201501345XA
Authority
SG
Singapore
Prior art keywords
toxicity test
mitochondrial toxicity
mitochondrial
test
toxicity
Prior art date
Application number
SG11201501345XA
Inventor
Fredrik Sjövall
Johannes Ehinger
Magnus Hansson
Eskil Elmer
Derek Gregory Batcheller
Original Assignee
Neurovive Pharmaceutical Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurovive Pharmaceutical Ab filed Critical Neurovive Pharmaceutical Ab
Publication of SG11201501345XA publication Critical patent/SG11201501345XA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5076Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
    • G01N33/5079Mitochondria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201501345XA 2012-10-05 2013-10-04 Mitochondrial toxicity test SG11201501345XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201270609 2012-10-05
PCT/EP2013/070666 WO2014053617A1 (en) 2012-10-05 2013-10-04 Mitochondrial toxicity test

Publications (1)

Publication Number Publication Date
SG11201501345XA true SG11201501345XA (en) 2015-03-30

Family

ID=47137411

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201501345XA SG11201501345XA (en) 2012-10-05 2013-10-04 Mitochondrial toxicity test

Country Status (19)

Country Link
US (1) US20150253306A1 (en)
EP (1) EP2904391B1 (en)
JP (1) JP6300806B2 (en)
KR (1) KR20150063557A (en)
CN (1) CN104704361B (en)
AU (1) AU2013326508A1 (en)
BR (1) BR112015007290A2 (en)
CA (1) CA2886921A1 (en)
CL (1) CL2015000789A1 (en)
EA (1) EA201590686A1 (en)
ES (1) ES2665522T3 (en)
HK (1) HK1207684A1 (en)
IL (1) IL237759B (en)
MX (1) MX2015003980A (en)
NZ (1) NZ630856A (en)
PH (1) PH12015500519B1 (en)
SG (1) SG11201501345XA (en)
TW (1) TWI616533B (en)
WO (1) WO2014053617A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104297442B (en) * 2014-11-03 2016-08-17 天津中医药大学 The application in terms of quickly detection early stage cardiac toxicity of the endogenous small-molecule substance
EP3693737B1 (en) 2015-03-27 2022-03-30 Agilent Technologies, Inc. Method and system for determining integrated metabolic baseline and potential of living cells
WO2020006118A1 (en) * 2018-06-26 2020-01-02 Ribonova Inc. Systems and methods for computing measurements for mitochondrial diseases
JP7030667B2 (en) 2018-09-28 2022-03-07 株式会社東芝 Power system accident cause estimation device, power system accident cause estimation system, power system accident cause estimation computer program and power system accident cause estimation method
US20220195481A1 (en) * 2019-05-17 2022-06-23 The Regents Of The University Of Califormia Mitochondrial respirometry in frozen specimens
CN111024937A (en) * 2019-11-20 2020-04-17 辉源生物科技(上海)有限公司 Method for detecting drug candidates having influence on liver mitochondrial function
CN111579763B (en) * 2020-04-09 2023-04-07 北京博瑞世安科技有限公司 Method for detecting respiratory function of leucocyte mitochondria and method for detecting kidney yin deficiency
CN111607632A (en) * 2020-05-29 2020-09-01 中国人民解放军陆军第八十二集团军医院 In-situ measuring method for mitochondrial respiratory function of muscle tissue
KR102273163B1 (en) * 2020-09-10 2021-07-05 주식회사 파이안바이오테크놀로지 Method for obtaining platelet-derived mitochondria and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2186636A1 (en) * 1994-03-30 1995-10-12 Corinna Herrnstadt Diagnosis, therapy and cellular and animal models for diseases associated with mitochondrial defects
CN1230531C (en) * 2002-12-09 2005-12-07 清华大学 Method and kit for separating cell particle from sample
US10920260B2 (en) * 2008-08-15 2021-02-16 Erasmus University Medical Center Rotterdam Methods and devices for assessment of mitochondrial function
US20130273557A1 (en) * 2010-05-26 2013-10-17 Valentin Gribkoff Compounds and methods of modulating mitochondrial bioenergetic efficiency through an interaction with atp synthase (complex v) and its subunits
US9581600B2 (en) * 2010-12-09 2017-02-28 André Arsenault In vitro mitochondrial function test (MFT) and uses thereof

Also Published As

Publication number Publication date
EP2904391A1 (en) 2015-08-12
CA2886921A1 (en) 2014-04-10
CL2015000789A1 (en) 2015-07-10
KR20150063557A (en) 2015-06-09
IL237759B (en) 2018-06-28
NZ630856A (en) 2016-08-26
JP2015535690A (en) 2015-12-17
WO2014053617A1 (en) 2014-04-10
JP6300806B2 (en) 2018-03-28
HK1207684A1 (en) 2016-02-05
TW201428106A (en) 2014-07-16
CN104704361B (en) 2018-01-16
MX2015003980A (en) 2015-07-06
PH12015500519A1 (en) 2015-04-27
TWI616533B (en) 2018-03-01
EA201590686A1 (en) 2015-07-30
AU2013326508A1 (en) 2015-03-19
EP2904391B1 (en) 2018-01-17
CN104704361A (en) 2015-06-10
ES2665522T3 (en) 2018-04-26
BR112015007290A2 (en) 2017-07-04
US20150253306A1 (en) 2015-09-10
PH12015500519B1 (en) 2015-04-27

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