HK1207585A1 - 含有馬鞭草烯酮衍生物的神經退行性疾病治療或者預防用藥物組合物 - Google Patents

含有馬鞭草烯酮衍生物的神經退行性疾病治療或者預防用藥物組合物

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Publication number
HK1207585A1
HK1207585A1 HK15108341.2A HK15108341A HK1207585A1 HK 1207585 A1 HK1207585 A1 HK 1207585A1 HK 15108341 A HK15108341 A HK 15108341A HK 1207585 A1 HK1207585 A1 HK 1207585A1
Authority
HK
Hong Kong
Prior art keywords
treating
pharmaceutical composition
composition containing
neurodegenerative disease
preventing neurodegenerative
Prior art date
Application number
HK15108341.2A
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English (en)
Inventor
金源起
崔容碩
宋受美
Original Assignee
Univ Korea Res & Bus Found
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Filing date
Publication date
Application filed by Univ Korea Res & Bus Found filed Critical Univ Korea Res & Bus Found
Publication of HK1207585A1 publication Critical patent/HK1207585A1/zh

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    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
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    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Coloring Foods And Improving Nutritive Qualities (AREA)
HK15108341.2A 2012-06-05 2015-08-27 含有馬鞭草烯酮衍生物的神經退行性疾病治療或者預防用藥物組合物 HK1207585A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20120060314 2012-06-05
PCT/KR2013/004932 WO2013183920A1 (ko) 2012-06-05 2013-06-04 베르베논 유도체를 함유하는 퇴행성 뇌질환 치료 또는 예방용 약학 조성물

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HK1207585A1 true HK1207585A1 (zh) 2016-02-05

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US (2) US9603842B2 (zh)
EP (1) EP2857007B1 (zh)
JP (1) JP5934839B2 (zh)
KR (1) KR101459612B1 (zh)
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AU (1) AU2013272429B2 (zh)
BR (1) BR112014030325B1 (zh)
CA (1) CA2875396C (zh)
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HK (1) HK1207585A1 (zh)
HU (1) HUE037638T2 (zh)
IL (1) IL236112B (zh)
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PT (1) PT2857007T (zh)
RU (1) RU2611349C2 (zh)
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TR (1) TR201807981T4 (zh)
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Families Citing this family (7)

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Publication number Priority date Publication date Assignee Title
US9603842B2 (en) 2012-06-05 2017-03-28 Korea University Research And Business Foundation Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease
WO2016122289A2 (ko) * 2015-01-30 2016-08-04 고려대학교산학협력단 베르베논 유도체를 포함하는 재관류 시술의 부작용을 감소 또는 예방하기 위한 조성물
US9447015B1 (en) * 2015-04-15 2016-09-20 Valent Biosciences Corporation (S)-2′-vinyl-abscisic acid derivatives
KR102008995B1 (ko) 2017-11-10 2019-08-08 충북대학교 산학협력단 산삼 유래 신규 화합물 및 이의 항혈전 용도
KR102145416B1 (ko) 2018-09-11 2020-08-19 신풍제약 주식회사 베르베논 유도체를 포함하는 암 치료 또는 예방용 조성물
JP7199534B2 (ja) 2018-11-14 2023-01-05 ネクスモス カンパニー リミテッド アプタマーを有効成分として含む退行性脳疾患の治療及び予防用組成物
KR102555329B1 (ko) * 2020-04-22 2023-07-17 신풍제약주식회사 베르베논 유도체를 포함하는 안구질환의 치료 또는 예방용 약학조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4036884A (en) * 1971-02-04 1977-07-19 So. Ci. Bre. Process for the manufacture of a new derivative of alpha-pinene and new medicaments based on this derivative
SE465649B (sv) * 1989-02-09 1991-10-14 Jan Loefquist Foerfarande foer bekaempning av den sextandade granbarkborren, pityogenes chalcographus, genom applicering av en inhibitoriskt aktiv maengd av (+) och/eller (-) -verbenon paa gran
IT1251615B (it) * 1991-10-04 1995-05-17 Golgi Sa Medicamento ad attivita' antielastasica.
US6214888B1 (en) * 1996-09-18 2001-04-10 Applied Genetics Incorporated Dermatological compounds
IT1312537B1 (it) * 1999-04-16 2002-04-22 Euphar Group Srl Derivati del (-)- verbenone.
AU2000238755A1 (en) * 2000-03-10 2001-09-24 Applied Genetics Incorporated Dermatics Dermatological compounds
US20040092583A1 (en) 2001-01-02 2004-05-13 Elizabeth Shanahan-Prendergast Treatment for inhibiting neoplastic lesions
US7270835B2 (en) 2001-06-20 2007-09-18 Metaproteomics, Llc Compositions that treat or inhibit pathological conditions associated with inflammatory response
RU2418577C1 (ru) * 2009-12-24 2011-05-20 Общество С Ограниченной Ответственностью "Томская Фармацевтическая Фабрика" (Ооо "Тфф") Средство для лечения болезни паркинсона
US9603842B2 (en) 2012-06-05 2017-03-28 Korea University Research And Business Foundation Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease

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