HK1206731A1 - Method for preparing substituted triazolopyridines - Google Patents
Method for preparing substituted triazolopyridines Download PDFInfo
- Publication number
- HK1206731A1 HK1206731A1 HK15107242.4A HK15107242A HK1206731A1 HK 1206731 A1 HK1206731 A1 HK 1206731A1 HK 15107242 A HK15107242 A HK 15107242A HK 1206731 A1 HK1206731 A1 HK 1206731A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- amino
- phenyl
- triazolo
- pyridin
- fluorophenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12175640.7 | 2012-07-10 | ||
| EP12175640 | 2012-07-10 | ||
| EP12185590 | 2012-09-24 | ||
| EP12185590.2 | 2012-09-24 | ||
| EP13170585 | 2013-06-05 | ||
| EP13170585.7 | 2013-06-05 | ||
| PCT/EP2013/064017 WO2014009219A1 (en) | 2012-07-10 | 2013-07-03 | Method for preparing substituted triazolopyridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1206731A1 true HK1206731A1 (en) | 2016-01-15 |
Family
ID=48793197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15107242.4A HK1206731A1 (en) | 2012-07-10 | 2013-07-03 | Method for preparing substituted triazolopyridines |
Country Status (24)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105431435A (zh) * | 2013-06-07 | 2016-03-23 | 拜耳制药股份公司 | 具有作为mps-1抑制剂的活性的取代的三唑并吡啶类 |
| PL3008062T3 (pl) * | 2013-06-11 | 2017-08-31 | Bayer Pharma Aktiengesellschaft | Pochodne proleki podstawionych triazolopirydyn |
| AU2014280354A1 (en) | 2013-06-11 | 2015-12-03 | Bayer Pharma Aktiengesellschaft | Combinations for the treatment of cancer comprising a Mps-1 kinase inhibitor and a mitotic inhibitor |
| WO2016166255A1 (en) | 2015-04-17 | 2016-10-20 | Netherlands Translational Research Center B.V. | Prognostic biomarkers for ttk inhibitor chemotherapy |
| TW201800408A (zh) | 2016-06-15 | 2018-01-01 | 拜耳製藥公司 | Mps-1抑制劑 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2003030937A1 (ja) * | 2001-10-05 | 2005-01-20 | 小野薬品工業株式会社 | ミトコンドリアルベンゾジアゼピン受容体アンタゴニストからなるストレス疾患の治療剤 |
| US20060074102A1 (en) * | 2004-05-14 | 2006-04-06 | Kevin Cusack | Kinase inhibitors as therapeutic agents |
| UA89503C2 (uk) * | 2004-09-13 | 2010-02-10 | Х. Луннбек А/С | Заміщені похідні аніліну |
| WO2006038116A2 (en) * | 2004-10-07 | 2006-04-13 | Warner-Lambert Company Llc | Triazolopyridine derivatives as antibacterial agents |
| US20060194823A1 (en) * | 2004-12-22 | 2006-08-31 | Georg Kettschau | Sulfonamido-macrocycles as Tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof |
| AR061229A1 (es) * | 2006-06-06 | 2008-08-13 | Schering Corp | Imidazopirazinas como inhibidores de la proteina quinasa |
| EP1870416A1 (en) * | 2006-06-21 | 2007-12-26 | Bayer Schering Pharma Aktiengesellschaft | Sulphonamido-macrocycles as tie2 inhibitors |
| MX2009002171A (es) | 2006-08-30 | 2009-05-28 | Cellzome Ltd | Derivados de triazol como inhibidores de cinasas. |
| JO3598B1 (ar) * | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| JP2010533680A (ja) | 2007-07-18 | 2010-10-28 | ノバルティス アーゲー | 二環ヘテロアリール化合物およびそれらのキナーゼ阻害剤としての使用 |
| US20110118238A1 (en) | 2007-08-23 | 2011-05-19 | Astrazeneca Ab | 2-anilinopurin-8-ones as inhibitors of ttk/mps1 for the treatment of proliferative disorders |
| MX2010002312A (es) | 2007-08-31 | 2010-03-18 | Merck Serono Sa | Compuestos de triazolopiridina y su uso como inhibidores de cinasa reguladora de señal de apoptosis. |
| GB0719803D0 (en) | 2007-10-10 | 2007-11-21 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| GB0724342D0 (en) * | 2007-12-13 | 2008-01-30 | Prolysis Ltd | Anitbacterial compositions |
| US8530689B2 (en) * | 2008-05-05 | 2013-09-10 | The Trustees Of The University Of Pennsylvania | Processes for the preparation of biphenyl compounds |
| EP2303890A4 (en) * | 2008-06-19 | 2012-04-11 | Progenics Pharm Inc | INHIBITORS OF PHOSPHATIDYLINOSITE-3-KINASE |
| MX2011008549A (es) | 2009-02-13 | 2011-12-06 | Fovea Pharmaceuticals | [1, 2, 4] triazolo [1 ,5 -a] piridinas como inhibidores de cinasa. |
| CN102413831B (zh) | 2009-04-29 | 2014-06-04 | 拜耳知识产权有限责任公司 | 取代的咪唑并喹喔啉 |
| WO2010141360A1 (en) * | 2009-06-05 | 2010-12-09 | Merck Sharp & Dohme Corp. | Biaryl benzotriazole derivatives |
| CN102459258B (zh) * | 2009-06-05 | 2015-11-25 | 赛福伦公司 | 1,2,4-三唑并[1,5a]吡啶衍生物的制备和用途 |
| WO2011026579A1 (en) | 2009-09-04 | 2011-03-10 | Bayer Schering Pharma Aktiengesellschaft | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors |
| EP2343294A1 (en) | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Substituted triazolopyridines |
| EP2343295A1 (en) | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Triazolopyridine derivates |
| EP2343297A1 (en) * | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Triazolopyridines |
| UY33452A (es) * | 2010-06-16 | 2012-01-31 | Bayer Schering Pharma Ag | Triazolopiridinas sustituidas |
| WO2012044567A2 (en) * | 2010-09-30 | 2012-04-05 | Merck Sharp & Dohme Corp. | Imidazole derivatives |
| EA023766B1 (ru) * | 2011-04-21 | 2016-07-29 | Байер Интеллектчуал Проперти Гмбх | Триазолопиридины |
| WO2012160029A1 (en) * | 2011-05-23 | 2012-11-29 | Bayer Intellectual Property Gmbh | Substituted triazolopyridines |
| UA112096C2 (uk) * | 2011-12-12 | 2016-07-25 | Байєр Інтеллектуал Проперті Гмбх | Заміщені триазолопіридини та їх застосування як інгібіторів ttk |
-
2013
- 2013-07-03 PE PE2015000017A patent/PE20150354A1/es not_active Application Discontinuation
- 2013-07-03 SG SG11201408419QA patent/SG11201408419QA/en unknown
- 2013-07-03 BR BR112015000308A patent/BR112015000308A2/pt not_active IP Right Cessation
- 2013-07-03 EP EP13737181.1A patent/EP2872506A1/en not_active Withdrawn
- 2013-07-03 NZ NZ703020A patent/NZ703020A/en not_active IP Right Cessation
- 2013-07-03 CA CA2878481A patent/CA2878481A1/en not_active Abandoned
- 2013-07-03 IN IN85DEN2015 patent/IN2015DN00085A/en unknown
- 2013-07-03 US US14/414,164 patent/US9388177B2/en not_active Expired - Fee Related
- 2013-07-03 MX MX2015000348A patent/MX2015000348A/es unknown
- 2013-07-03 KR KR20157000338A patent/KR20150040845A/ko not_active Withdrawn
- 2013-07-03 JP JP2015520907A patent/JP6238979B2/ja not_active Expired - Fee Related
- 2013-07-03 WO PCT/EP2013/064017 patent/WO2014009219A1/en active Application Filing
- 2013-07-03 AU AU2013289381A patent/AU2013289381A1/en not_active Abandoned
- 2013-07-03 CN CN201380045913.9A patent/CN104603136B/zh not_active Expired - Fee Related
- 2013-07-03 HK HK15107242.4A patent/HK1206731A1/xx unknown
- 2013-07-03 EA EA201590116A patent/EA027544B1/ru not_active IP Right Cessation
- 2013-07-03 AP AP2014008177A patent/AP3778A/en active
-
2014
- 2014-12-15 IL IL236265A patent/IL236265A/en not_active IP Right Cessation
-
2015
- 2015-01-07 TN TNP2015000008A patent/TN2015000008A1/fr unknown
- 2015-01-08 CL CL2015000038A patent/CL2015000038A1/es unknown
- 2015-01-09 PH PH12015500061A patent/PH12015500061A1/en unknown
- 2015-01-09 DO DO2015000007A patent/DOP2015000007A/es unknown
- 2015-01-09 CR CR20150006A patent/CR20150006A/es unknown
- 2015-01-09 CO CO15004251A patent/CO7160002A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IN2015DN00085A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-05-29 |
| AU2013289381A1 (en) | 2015-01-22 |
| TN2015000008A1 (en) | 2016-06-29 |
| SG11201408419QA (en) | 2015-01-29 |
| CO7160002A2 (es) | 2015-01-15 |
| US20150148542A1 (en) | 2015-05-28 |
| KR20150040845A (ko) | 2015-04-15 |
| WO2014009219A1 (en) | 2014-01-16 |
| AP3778A (en) | 2016-08-31 |
| CR20150006A (es) | 2015-02-16 |
| PH12015500061A1 (en) | 2015-03-02 |
| EA201590116A1 (ru) | 2015-07-30 |
| IL236265A (en) | 2017-07-31 |
| MX2015000348A (es) | 2015-04-14 |
| DOP2015000007A (es) | 2015-02-15 |
| EA027544B1 (ru) | 2017-08-31 |
| EP2872506A1 (en) | 2015-05-20 |
| BR112015000308A2 (pt) | 2017-06-27 |
| JP6238979B2 (ja) | 2017-11-29 |
| JP2015523372A (ja) | 2015-08-13 |
| US9388177B2 (en) | 2016-07-12 |
| PE20150354A1 (es) | 2015-03-21 |
| CN104603136B (zh) | 2017-06-27 |
| NZ703020A (en) | 2017-08-25 |
| CN104603136A (zh) | 2015-05-06 |
| AP2014008177A0 (en) | 2014-12-31 |
| CA2878481A1 (en) | 2014-01-16 |
| IL236265A0 (en) | 2015-02-26 |
| CL2015000038A1 (es) | 2015-03-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2791136B1 (en) | Substituted triazolopyridines and their use as ttk inhibitors | |
| EA023766B1 (ru) | Триазолопиридины | |
| CN104603136B (zh) | 制备取代的三唑并吡啶的方法 | |
| KR20220042293A (ko) | 질소 함유 다환 축합 고리계 화합물, 이의 약학 조성물, 제조 방법 및 용도 | |
| EP3008062B1 (en) | Prodrug derivatives of substituted triazolopyridines | |
| JP2016527193A (ja) | 置換トリアゾロピリジン | |
| EP3004092B1 (en) | Substituted triazolopyridines | |
| HK1203200B (en) | Substituted triazolopyridines and their use as ttk inhibitors | |
| HK1222652B (en) | Substituted triazolopyridines | |
| HK1182708A (en) | Substituted triazolopyridines | |
| HK1234732A1 (en) | Novel compounds |