HK1204340A1 - 用於器官移植排斥的蛋白質及基因生物標志物 - Google Patents
用於器官移植排斥的蛋白質及基因生物標志物Info
- Publication number
- HK1204340A1 HK1204340A1 HK15104780.9A HK15104780A HK1204340A1 HK 1204340 A1 HK1204340 A1 HK 1204340A1 HK 15104780 A HK15104780 A HK 15104780A HK 1204340 A1 HK1204340 A1 HK 1204340A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- rejection
- protein
- organ transplants
- gene biomarkers
- biomarkers
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
- G01N2800/245—Transplantation related diseases, e.g. graft versus host disease
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34107110P | 2010-03-25 | 2010-03-25 | |
US201161452288P | 2011-03-14 | 2011-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1204340A1 true HK1204340A1 (zh) | 2015-11-13 |
Family
ID=44673660
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15104780.9A HK1204340A1 (zh) | 2010-03-25 | 2015-05-19 | 用於器官移植排斥的蛋白質及基因生物標志物 |
Country Status (6)
Country | Link |
---|---|
US (3) | US9535075B2 (zh) |
EP (2) | EP2550371A4 (zh) |
CA (1) | CA2794255C (zh) |
ES (1) | ES2798114T3 (zh) |
HK (1) | HK1204340A1 (zh) |
WO (1) | WO2011119980A1 (zh) |
Families Citing this family (25)
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WO2011006119A2 (en) | 2009-07-09 | 2011-01-13 | The Scripps Research Institute | Gene expression profiles associated with chronic allograft nephropathy |
CN102854323B (zh) * | 2011-12-23 | 2013-08-07 | 中国人民解放军第三〇九医院 | 移植肾排斥反应早期诊断试剂盒及其使用方法 |
CN102854306B (zh) * | 2011-12-23 | 2013-08-07 | 中国人民解放军第三〇九医院 | 用于预警肾移植后排斥反应的试剂盒及其使用方法 |
CN102854305B (zh) * | 2011-12-23 | 2013-08-07 | 中国人民解放军第三〇九医院 | 移植肾排斥反应预警试剂盒及其使用方法 |
WO2013187556A1 (en) * | 2012-06-14 | 2013-12-19 | Scripps Korea Antibody Institute | Novel antibody specific for clec14a and uses thereof |
EP2698636A1 (en) | 2012-08-13 | 2014-02-19 | Fundació Institut d'Investigació Biomèdica de Bellvitge | Methods and reagents for prevention and/or treatment of transplant rejection |
US9816088B2 (en) | 2013-03-15 | 2017-11-14 | Abvitro Llc | Single cell bar-coding for antibody discovery |
WO2015035203A1 (en) * | 2013-09-06 | 2015-03-12 | Immucor Gti Diagnostics, Inc. | Compositions and methods for assessing acute rejection in renal transplantation |
US20160376652A1 (en) * | 2013-09-06 | 2016-12-29 | Immucor Gti Diagnostics, Inc. | Compositions and methods for diagnosis and prediction of solid organ graft rejection |
CN103698508B (zh) * | 2014-01-08 | 2016-05-18 | 陈娟 | 一种结缔组织病早期肺间质病变诊断试剂盒 |
WO2015138803A1 (en) * | 2014-03-12 | 2015-09-17 | Icahn School Of Medicine At Mount Sinai | Method for identifying kidney allograft recipients at risk for chronic injury |
US11104951B2 (en) | 2014-05-22 | 2021-08-31 | The Scripps Research Institute | Molecular signatures for distinguishing liver transplant rejections or injuries |
EP3825418A3 (en) * | 2014-05-22 | 2021-09-15 | The Scripps Research Institute | Molecular signatures for distinguishing liver transplant rejections or injuries |
US10443100B2 (en) | 2014-05-22 | 2019-10-15 | The Scripps Research Institute | Gene expression profiles associated with sub-clinical kidney transplant rejection |
US11572587B2 (en) | 2014-06-26 | 2023-02-07 | Icahn School Of Medicine At Mount Sinai | Method for diagnosing subclinical and clinical acute rejection by analysis of predictive gene sets |
CN104198691B (zh) * | 2014-08-14 | 2016-08-17 | 上海睿康生物科技有限公司 | 一种稳定的α-淀粉酶检测试剂盒 |
EP3194593B1 (en) | 2014-09-15 | 2019-02-06 | AbVitro LLC | High-throughput nucleotide library sequencing |
WO2016075232A1 (en) * | 2014-11-12 | 2016-05-19 | Institut National De La Sante Et De La Recherche Medicale | Gene signature associated with tolerance to renal allograft |
WO2017066390A1 (en) * | 2015-10-13 | 2017-04-20 | The Trustees Of The University Of Pennsylvania | Methods for using enriched exosomes as a platform for monitoring organ status |
WO2017100259A1 (en) * | 2015-12-08 | 2017-06-15 | Icahn School Of Medicine At Mount Sinai | Pretransplant prediction of post-transplant acute rejection |
WO2019107673A1 (ko) * | 2017-11-29 | 2019-06-06 | 서울대학교병원 | Abo 혈액형 부적합 이식시의 항체-매개성 거부반응의 모니터링을 위한 바이오마커 |
CN112236137A (zh) | 2018-04-16 | 2021-01-15 | 西奈山伊坎医学院 | 利用移植前接受者血液中转录组标志预测急性排斥反应和肾脏同种异体移植物丧失的方法和试剂盒 |
JP2022531660A (ja) * | 2019-05-06 | 2022-07-08 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 移植拒絶反応の非hlaマーカー |
EP4177608A1 (en) | 2021-11-05 | 2023-05-10 | Medizinische Hochschule Hannover | Biomarker panel for diagnosing pulmonary dysfunction |
WO2024068521A1 (en) * | 2022-09-26 | 2024-04-04 | Fundación Para La Formación E Investigación Sanitaria De La Región De Murcia | In vitro method for predicting organ transplant rejection |
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US20030104371A1 (en) | 1997-09-24 | 2003-06-05 | Strom Terry B. | Methods of evaluating transplant rejection |
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US6607879B1 (en) | 1998-02-09 | 2003-08-19 | Incyte Corporation | Compositions for the detection of blood cell and immunological response gene expression |
US6235311B1 (en) | 1998-03-18 | 2001-05-22 | Bristol-Myers Squibb Company | Pharmaceutical composition containing a combination of a statin and aspirin and method |
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US20110189680A1 (en) * | 2008-05-30 | 2011-08-04 | The University Of British Columbia | Methods of Diagnosing Rejection of a Kidney Allograft Using Genomic or Proteomic Expression Profiling |
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US20110201519A1 (en) | 2008-08-18 | 2011-08-18 | Sarwal Minnie M | Methods and Compositions for Determining a Graft Tolerant Phenotype in a Subject |
KR100928403B1 (ko) | 2008-10-01 | 2009-11-26 | 경북대학교 산학협력단 | 티지비엠 신증의 진단용 조성물 및 키트 |
EP2387618B1 (en) * | 2009-01-15 | 2014-05-21 | The Board of Trustees of The Leland Stanford Junior University | Biomarker panel for diagnosis and prediction of graft rejection |
US8734786B2 (en) | 2009-09-16 | 2014-05-27 | Northwestern University | Use of ECDI-fixed cell tolerance as a method for preventing allograft rejection |
CN103154736B (zh) | 2010-05-13 | 2016-04-06 | 新泽西医科和牙科大学 | 用于检测和诊断神经变性疾病的诊断性自身抗体谱 |
-
2011
- 2011-03-25 US US13/635,667 patent/US9535075B2/en active Active
- 2011-03-25 EP EP11760327.4A patent/EP2550371A4/en not_active Withdrawn
- 2011-03-25 EP EP14168535.4A patent/EP2803735B1/en active Active
- 2011-03-25 CA CA2794255A patent/CA2794255C/en active Active
- 2011-03-25 WO PCT/US2011/030026 patent/WO2011119980A1/en active Application Filing
- 2011-03-25 ES ES14168535T patent/ES2798114T3/es active Active
-
2015
- 2015-05-19 HK HK15104780.9A patent/HK1204340A1/zh unknown
-
2016
- 2016-11-22 US US15/359,308 patent/US20170227549A1/en not_active Abandoned
-
2021
- 2021-01-29 US US17/162,093 patent/US11768208B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2550371A1 (en) | 2013-01-30 |
WO2011119980A1 (en) | 2011-09-29 |
US20210199669A1 (en) | 2021-07-01 |
EP2803735A1 (en) | 2014-11-19 |
EP2803735B1 (en) | 2020-03-25 |
US11768208B2 (en) | 2023-09-26 |
EP2550371A4 (en) | 2013-11-20 |
US20170227549A1 (en) | 2017-08-10 |
US20130143755A1 (en) | 2013-06-06 |
CA2794255C (en) | 2020-01-14 |
US9535075B2 (en) | 2017-01-03 |
CA2794255A1 (en) | 2011-09-29 |
ES2798114T3 (es) | 2020-12-09 |
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