HK1202876A1 - 改进的合成 - Google Patents

改进的合成 Download PDF

Info

Publication number
HK1202876A1
HK1202876A1 HK15103375.2A HK15103375A HK1202876A1 HK 1202876 A1 HK1202876 A1 HK 1202876A1 HK 15103375 A HK15103375 A HK 15103375A HK 1202876 A1 HK1202876 A1 HK 1202876A1
Authority
HK
Hong Kong
Prior art keywords
provides
present
improved synthesis
class
steroid
Prior art date
Application number
HK15103375.2A
Other languages
English (en)
Chinese (zh)
Inventor
Andrew Clive MUSCROFT-TAYLOR
Philip Andrew MARSHALL
Jennifer Mary Mason
David Millar WALKER
Original Assignee
Oncology Research International Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012902119A external-priority patent/AU2012902119A0/en
Application filed by Oncology Research International Limited filed Critical Oncology Research International Limited
Publication of HK1202876A1 publication Critical patent/HK1202876A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005—Glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15103375.2A 2012-05-23 2013-04-24 改进的合成 HK1202876A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2012902119 2012-05-23
AU2012902119A AU2012902119A0 (en) 2012-05-23 Improved synthesis
AU2013204005 2013-04-11
AU2013204005A AU2013204005B2 (en) 2012-05-23 2013-04-11 Improved synthesis
PCT/AU2013/000416 WO2013173862A1 (en) 2012-05-23 2013-04-24 Improved synthesis

Publications (1)

Publication Number Publication Date
HK1202876A1 true HK1202876A1 (zh) 2015-10-09

Family

ID=49622929

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15103375.2A HK1202876A1 (zh) 2012-05-23 2013-04-24 改进的合成

Country Status (13)

Country Link
US (1) US20150105543A1 (https=)
EP (1) EP2852607B1 (https=)
JP (1) JP2015517535A (https=)
CN (1) CN104395333B (https=)
AU (1) AU2013204005B2 (https=)
BR (1) BR112014029189A2 (https=)
CA (1) CA2874030A1 (https=)
EA (1) EA201492194A1 (https=)
HK (1) HK1202876A1 (https=)
IN (1) IN2014DN10846A (https=)
MX (1) MX356853B (https=)
TW (1) TWI609025B (https=)
WO (1) WO2013173862A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103193858B (zh) * 2013-04-12 2016-08-03 中国海洋大学 螺甾碱烷型糖苷生物碱的合成方法
AU2018217439B2 (en) * 2017-02-10 2021-11-25 Oncology Research International Limited Steroid saponins with anti-cancer activity
CN110790811A (zh) * 2019-10-10 2020-02-14 华南农业大学 双相体系氯化铝水解制备薯蓣皂素方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1115346C (zh) * 2000-10-20 2003-07-23 中国科学院上海有机化学研究所 鼠李糖取代的β－D－葡萄糖基－薯蓣皂甙的皂甙库、制备方法和用途
CN101130568B (zh) * 2007-09-07 2011-06-15 中国科学院上海有机化学研究所 一类喷脑皂甙类化合物、合成方法及其用途
JP5706815B2 (ja) * 2008-04-08 2015-04-22 スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ トリテルペンであるサポニン、その合成法および使用
CN101635335B (zh) * 2008-07-25 2013-02-27 深圳市比克电池有限公司 圆柱电池卷芯入壳机

Also Published As

Publication number Publication date
EA201492194A1 (ru) 2015-04-30
TWI609025B (zh) 2017-12-21
EP2852607A4 (en) 2016-02-24
BR112014029189A2 (pt) 2017-06-27
AU2013204005B2 (en) 2015-04-16
MX2014014056A (es) 2015-08-14
EP2852607A1 (en) 2015-04-01
IN2014DN10846A (https=) 2015-09-04
TW201350497A (zh) 2013-12-16
AU2013204005A1 (en) 2013-12-12
CA2874030A1 (en) 2013-11-28
MX356853B (es) 2018-06-18
CN104395333B (zh) 2018-01-02
CN104395333A (zh) 2015-03-04
WO2013173862A1 (en) 2013-11-28
EP2852607B1 (en) 2018-10-24
US20150105543A1 (en) 2015-04-16
JP2015517535A (ja) 2015-06-22

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