BR112014029189A2 - síntese aperfeiçoada - Google Patents
síntese aperfeiçoadaInfo
- Publication number
- BR112014029189A2 BR112014029189A2 BR112014029189A BR112014029189A BR112014029189A2 BR 112014029189 A2 BR112014029189 A2 BR 112014029189A2 BR 112014029189 A BR112014029189 A BR 112014029189A BR 112014029189 A BR112014029189 A BR 112014029189A BR 112014029189 A2 BR112014029189 A2 BR 112014029189A2
- Authority
- BR
- Brazil
- Prior art keywords
- improved synthesis
- provides
- present
- class
- steroid saponin
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 3
- 238000003786 synthesis reaction Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 150000005856 steroid saponins Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 229930002600 steroidal saponin Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J17/005—Glycosides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012902119A AU2012902119A0 (en) | 2012-05-23 | Improved synthesis | |
| AU2013204005A AU2013204005B2 (en) | 2012-05-23 | 2013-04-11 | Improved synthesis |
| PCT/AU2013/000416 WO2013173862A1 (en) | 2012-05-23 | 2013-04-24 | Improved synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014029189A2 true BR112014029189A2 (pt) | 2017-06-27 |
Family
ID=49622929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014029189A BR112014029189A2 (pt) | 2012-05-23 | 2013-04-24 | síntese aperfeiçoada |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20150105543A1 (https=) |
| EP (1) | EP2852607B1 (https=) |
| JP (1) | JP2015517535A (https=) |
| CN (1) | CN104395333B (https=) |
| AU (1) | AU2013204005B2 (https=) |
| BR (1) | BR112014029189A2 (https=) |
| CA (1) | CA2874030A1 (https=) |
| EA (1) | EA201492194A1 (https=) |
| HK (1) | HK1202876A1 (https=) |
| IN (1) | IN2014DN10846A (https=) |
| MX (1) | MX356853B (https=) |
| TW (1) | TWI609025B (https=) |
| WO (1) | WO2013173862A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103193858B (zh) * | 2013-04-12 | 2016-08-03 | 中国海洋大学 | 螺甾碱烷型糖苷生物碱的合成方法 |
| AU2018217439B2 (en) * | 2017-02-10 | 2021-11-25 | Oncology Research International Limited | Steroid saponins with anti-cancer activity |
| CN110790811A (zh) * | 2019-10-10 | 2020-02-14 | 华南农业大学 | 双相体系氯化铝水解制备薯蓣皂素方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1115346C (zh) * | 2000-10-20 | 2003-07-23 | 中国科学院上海有机化学研究所 | 鼠李糖取代的β－D－葡萄糖基－薯蓣皂甙的皂甙库、制备方法和用途 |
| CN101130568B (zh) * | 2007-09-07 | 2011-06-15 | 中国科学院上海有机化学研究所 | 一类喷脑皂甙类化合物、合成方法及其用途 |
| JP5706815B2 (ja) * | 2008-04-08 | 2015-04-22 | スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ | トリテルペンであるサポニン、その合成法および使用 |
| CN101635335B (zh) * | 2008-07-25 | 2013-02-27 | 深圳市比克电池有限公司 | 圆柱电池卷芯入壳机 |
-
2013
- 2013-04-11 AU AU2013204005A patent/AU2013204005B2/en active Active
- 2013-04-24 WO PCT/AU2013/000416 patent/WO2013173862A1/en not_active Ceased
- 2013-04-24 IN IN10846DEN2014 patent/IN2014DN10846A/en unknown
- 2013-04-24 HK HK15103375.2A patent/HK1202876A1/xx unknown
- 2013-04-24 US US14/403,110 patent/US20150105543A1/en not_active Abandoned
- 2013-04-24 CA CA2874030A patent/CA2874030A1/en not_active Abandoned
- 2013-04-24 EA EA201492194A patent/EA201492194A1/ru unknown
- 2013-04-24 BR BR112014029189A patent/BR112014029189A2/pt not_active IP Right Cessation
- 2013-04-24 JP JP2015512969A patent/JP2015517535A/ja not_active Ceased
- 2013-04-24 CN CN201380034397.XA patent/CN104395333B/zh active Active
- 2013-04-24 MX MX2014014056A patent/MX356853B/es active IP Right Grant
- 2013-04-24 EP EP13794398.1A patent/EP2852607B1/en not_active Not-in-force
- 2013-05-17 TW TW102117564A patent/TWI609025B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EA201492194A1 (ru) | 2015-04-30 |
| TWI609025B (zh) | 2017-12-21 |
| EP2852607A4 (en) | 2016-02-24 |
| AU2013204005B2 (en) | 2015-04-16 |
| MX2014014056A (es) | 2015-08-14 |
| EP2852607A1 (en) | 2015-04-01 |
| IN2014DN10846A (https=) | 2015-09-04 |
| HK1202876A1 (zh) | 2015-10-09 |
| TW201350497A (zh) | 2013-12-16 |
| AU2013204005A1 (en) | 2013-12-12 |
| CA2874030A1 (en) | 2013-11-28 |
| MX356853B (es) | 2018-06-18 |
| CN104395333B (zh) | 2018-01-02 |
| CN104395333A (zh) | 2015-03-04 |
| WO2013173862A1 (en) | 2013-11-28 |
| EP2852607B1 (en) | 2018-10-24 |
| US20150105543A1 (en) | 2015-04-16 |
| JP2015517535A (ja) | 2015-06-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2017225061B2 (en) | Biomarkers and methods of treating PD-1 and PD-L1 related conditions | |
| MX2018005061A (es) | Compuestos de interacción con glicanos y métodos de uso. | |
| MX2017010836A (es) | Panel biomarcador para la deteccion de cancer. | |
| CO2017003396A2 (es) | Esteroides neuroactivos, composiciones y usos de los mismos | |
| SMT202000346T1 (it) | 19-norsteroidi neuroattivi per metodi di trattamento | |
| HUE046800T2 (hu) | Idegre ható szteroidkészítmények, amelyek allopregnanolon és szulfobutil-éter-ß-ciklodextrin komplexet tartalmaznak | |
| WO2014160441A8 (en) | Neuroactive steroids, compositions, and uses thereof | |
| AR094195A1 (es) | Enjuagues bucales de haluros de zinc aminoacidos | |
| BR112017001031A2 (pt) | apresentação assistida de janelas de aplicativo | |
| PL3488852T3 (pl) | Neuroaktywne steroidy, kompozycje i ich zastosowania | |
| BR122019026188A8 (pt) | Métodos para determinar se um indivíduo tem doença hepática gordurosa não alcoólica (nafld), se um indivíduo com esteatose não alcoólica tem esteato-hepatite não alcoólica e para monitorar um indivíduo com esteatose não alcoólica para o desenvolvimento de nash | |
| BR112016002391A2 (pt) | composições tópicas e métodos de uso das mesmas | |
| BR112016019836A2 (pt) | método para analisar uma amostra de um sujeito, dispositivo de diagnóstico para utilização no diagnóstico da endometriose, kit, uso de um biomarcador, e, método para aumentar uma resposta de anticorpos em um sujeito | |
| EA201790884A1 (ru) | 6-алкил-7-гидрокси-4-ен-3-оновые стероиды в качестве промежуточных соединений для получения стероидных модуляторов fxr | |
| EP2966445A4 (en) | TINTANT FOR DYING OF TISSUE, MANUFACTURING PROCESS FOR TINTING AGENT FOR TISSUE AND TISSUE COLORING TINTANT FOR TISSUE COLORING | |
| EA201790881A1 (ru) | 5-бета-6-алкил-7-гидрокси-3-оновые стероиды в качестве промежуточных соединений для получения стероидных модуляторов fxr | |
| EP2996721A4 (en) | Methods and compositions for prognosis, diagnosis and treatment of adam8-expressing cancer | |
| EP2977760A4 (en) | Biomarker for diagnosing liver cancer | |
| HK1218860A1 (zh) | 卵巢癌疫苗及接种方法 | |
| BR112014029189A2 (pt) | síntese aperfeiçoada | |
| BR112015030310A2 (pt) | testemunhagem através de revestimento | |
| BR112019011286A2 (pt) | métodos para produzir uma composição de lipossoma, para preparar uma composição de vacina e para preparar um kit de vacina. | |
| CO7160028A2 (es) | Proteínas de la membrana exterior de histophilus somni y sus métodos antecedentes de la invención | |
| BR112013028218A2 (pt) | válvula para fabricação de solas de calçado ocas e método para uso das mesmas | |
| PL2860487T3 (pl) | Narzędzie pomiarowe do przygotowania okładziny okiennej, zestaw instalacyjny zawierający takie narządzie pomiarowe oraz sposób przygotowania okładziny okiennej |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2515 DE 19-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |