EA201492194A1 - Усовершенствованный синтез - Google Patents

Усовершенствованный синтез

Info

Publication number
EA201492194A1
EA201492194A1 EA201492194A EA201492194A EA201492194A1 EA 201492194 A1 EA201492194 A1 EA 201492194A1 EA 201492194 A EA201492194 A EA 201492194A EA 201492194 A EA201492194 A EA 201492194A EA 201492194 A1 EA201492194 A1 EA 201492194A1
Authority
EA
Eurasian Patent Office
Prior art keywords
relates
present
improved synthesis
class
preparation
Prior art date
Application number
EA201492194A
Other languages
English (en)
Russian (ru)
Inventor
Эндрю Клайв Маскрофт-Тэйлор
Филип Эндрю Маршалл
Дженифер Мэри Мэйсон
Дэвид Миллар Уолкер
Original Assignee
Онколоджи Рисерч Интернешнл Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012902119A external-priority patent/AU2012902119A0/en
Application filed by Онколоджи Рисерч Интернешнл Лимитед filed Critical Онколоджи Рисерч Интернешнл Лимитед
Publication of EA201492194A1 publication Critical patent/EA201492194A1/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005Glycosides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/256Polyterpene radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EA201492194A 2012-05-23 2013-04-24 Усовершенствованный синтез EA201492194A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2012902119A AU2012902119A0 (en) 2012-05-23 Improved synthesis
AU2013204005A AU2013204005B2 (en) 2012-05-23 2013-04-11 Improved synthesis
PCT/AU2013/000416 WO2013173862A1 (en) 2012-05-23 2013-04-24 Improved synthesis

Publications (1)

Publication Number Publication Date
EA201492194A1 true EA201492194A1 (ru) 2015-04-30

Family

ID=49622929

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201492194A EA201492194A1 (ru) 2012-05-23 2013-04-24 Усовершенствованный синтез

Country Status (13)

Country Link
US (1) US20150105543A1 (https=)
EP (1) EP2852607B1 (https=)
JP (1) JP2015517535A (https=)
CN (1) CN104395333B (https=)
AU (1) AU2013204005B2 (https=)
BR (1) BR112014029189A2 (https=)
CA (1) CA2874030A1 (https=)
EA (1) EA201492194A1 (https=)
HK (1) HK1202876A1 (https=)
IN (1) IN2014DN10846A (https=)
MX (1) MX356853B (https=)
TW (1) TWI609025B (https=)
WO (1) WO2013173862A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103193858B (zh) * 2013-04-12 2016-08-03 中国海洋大学 螺甾碱烷型糖苷生物碱的合成方法
AU2018217439B2 (en) * 2017-02-10 2021-11-25 Oncology Research International Limited Steroid saponins with anti-cancer activity
CN110790811A (zh) * 2019-10-10 2020-02-14 华南农业大学 双相体系氯化铝水解制备薯蓣皂素方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1115346C (zh) * 2000-10-20 2003-07-23 中国科学院上海有机化学研究所 鼠李糖取代的β-D-葡萄糖基-薯蓣皂甙的皂甙库、制备方法和用途
CN101130568B (zh) * 2007-09-07 2011-06-15 中国科学院上海有机化学研究所 一类喷脑皂甙类化合物、合成方法及其用途
JP5706815B2 (ja) * 2008-04-08 2015-04-22 スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ トリテルペンであるサポニン、その合成法および使用
CN101635335B (zh) * 2008-07-25 2013-02-27 深圳市比克电池有限公司 圆柱电池卷芯入壳机

Also Published As

Publication number Publication date
TWI609025B (zh) 2017-12-21
EP2852607A4 (en) 2016-02-24
BR112014029189A2 (pt) 2017-06-27
AU2013204005B2 (en) 2015-04-16
MX2014014056A (es) 2015-08-14
EP2852607A1 (en) 2015-04-01
IN2014DN10846A (https=) 2015-09-04
HK1202876A1 (zh) 2015-10-09
TW201350497A (zh) 2013-12-16
AU2013204005A1 (en) 2013-12-12
CA2874030A1 (en) 2013-11-28
MX356853B (es) 2018-06-18
CN104395333B (zh) 2018-01-02
CN104395333A (zh) 2015-03-04
WO2013173862A1 (en) 2013-11-28
EP2852607B1 (en) 2018-10-24
US20150105543A1 (en) 2015-04-16
JP2015517535A (ja) 2015-06-22

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