HK1202458A1 - 用於治療糖尿病的葡萄糖激酶活化劑組合物 - Google Patents
用於治療糖尿病的葡萄糖激酶活化劑組合物Info
- Publication number
- HK1202458A1 HK1202458A1 HK15103235.2A HK15103235A HK1202458A1 HK 1202458 A1 HK1202458 A1 HK 1202458A1 HK 15103235 A HK15103235 A HK 15103235A HK 1202458 A1 HK1202458 A1 HK 1202458A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- diabetes
- treatment
- glucokinase activator
- activator compositions
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261648110P | 2012-05-17 | 2012-05-17 | |
PCT/US2013/041076 WO2013173417A2 (en) | 2012-05-17 | 2013-05-15 | Glucokinase activator compositions for the treatment of diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1202458A1 true HK1202458A1 (zh) | 2015-10-02 |
Family
ID=48576527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15103235.2A HK1202458A1 (zh) | 2012-05-17 | 2015-03-31 | 用於治療糖尿病的葡萄糖激酶活化劑組合物 |
Country Status (16)
Country | Link |
---|---|
US (3) | US10004782B2 (zh) |
EP (1) | EP2849776B1 (zh) |
JP (1) | JP6234443B2 (zh) |
KR (2) | KR102371364B1 (zh) |
CN (1) | CN104349790A (zh) |
AU (2) | AU2013262895A1 (zh) |
BR (1) | BR112014028622A2 (zh) |
CA (1) | CA2872021C (zh) |
EA (1) | EA201492109A1 (zh) |
ES (1) | ES2878001T3 (zh) |
HK (1) | HK1202458A1 (zh) |
IL (1) | IL235484A0 (zh) |
IN (1) | IN2014DN09554A (zh) |
MX (1) | MX360304B (zh) |
SG (2) | SG10201609644UA (zh) |
WO (1) | WO2013173417A2 (zh) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2799591C (en) | 2010-05-26 | 2019-06-11 | Transtech Pharma, Inc. | Use of metformin in combination with a glucokinase activator and compositions comprising metformin and a glucokinase activator |
KR102371364B1 (ko) | 2012-05-17 | 2022-03-07 | 브이티브이 테라퓨틱스 엘엘씨 | 당뇨병 치료를 위한 글루코키나아제 활성화제 조성물 |
KR102408480B1 (ko) | 2018-05-30 | 2022-06-10 | 이삼구 | 당뇨질환의 치료용 조성물 |
WO2019228366A1 (zh) * | 2018-05-31 | 2019-12-05 | 华领医药技术(上海)有限公司 | 含葡萄糖激酶激活剂和α-葡萄糖苷酶抑制剂的药物组合、组合物和制剂及其制备方法和用途 |
CN112040945A (zh) * | 2018-06-12 | 2020-12-04 | Vtv治疗有限责任公司 | 葡萄糖激酶激活剂与胰岛素或胰岛素类似物组合的治疗用途 |
AU2020426356A1 (en) * | 2020-01-31 | 2022-08-25 | Hua Medicine (Shanghai) Ltd. | Treating treatment-resistant diabetes with glucokinase activator |
US11872221B2 (en) | 2020-01-31 | 2024-01-16 | Hua Medicine (Shanghai) Ltd. | Treating untreated or treatment-resistant diabetes with glucokinase activator |
US11857536B2 (en) | 2020-06-04 | 2024-01-02 | Hua Medicine (Shanghai) Ltd. | Glucokinase activator for treating diabetes with renal impairment |
WO2021243645A1 (en) * | 2020-06-04 | 2021-12-09 | Hua Medicine (Shanghai) Ltd. | Glucokinase activator for treating diabetes with renal impairment |
CN116056760A (zh) * | 2020-06-08 | 2023-05-02 | 维特卫治疗有限责任公司 | {2-[3-环己基-3-(反式-4-丙氧基-环己基)-脲基]-噻唑-5-基硫烷基}-乙酸的结晶形式及其用途 |
KR20230048502A (ko) * | 2020-06-08 | 2023-04-11 | 브이티브이 테라퓨틱스 엘엘씨 | {2-[3-사이클로헥실-3-(트랜스-4-프로폭시-사이클로헥실)-우레이도]-티아졸-5-일설파닐}-아세트산의 염 또는 공결정 및 그의 용도 |
CN115350268A (zh) * | 2022-08-24 | 2022-11-18 | 深圳青澜生物技术有限公司 | 一种用于治疗糖尿病的制剂、微针及其制备工艺 |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
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AT323195B (de) | 1973-03-16 | 1975-06-25 | Hurka Wilhelm | Verfahren zur herstellung neuer salze von biguaniden |
FR2243684B1 (zh) | 1973-09-19 | 1977-01-28 | Semb | |
US5552160A (en) | 1991-01-25 | 1996-09-03 | Nanosystems L.L.C. | Surface modified NSAID nanoparticles |
US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
US6794412B1 (en) * | 1999-03-11 | 2004-09-21 | Bristol-Myers Squibb Pharma Company | Treatment of thrombosis by combined use of a factor Xa inhibitor and aspirin |
DE60036367T2 (de) * | 1999-06-21 | 2008-05-29 | Eli Lilly And Co., Indianapolis | Synergitische verwendung von thiazolidinedionen und glucagon-ähnlichem peptid-1 und dessen agonisten für die behandlung von nicht-insulin-abhängigen diabetes |
US6294546B1 (en) * | 1999-08-30 | 2001-09-25 | The Broad Of Trustees Of The Leland Stanford Junior University | Uses of diterpenoid triepoxides as an anti-proliferative agent |
US6608038B2 (en) * | 2000-03-15 | 2003-08-19 | Novartis Ag | Methods and compositions for treatment of diabetes and related conditions via gene therapy |
CA2744893A1 (en) | 2002-06-27 | 2004-01-08 | Novo Nordisk A/S | Aryl carbonyl derivatives as glucokinase activators |
JP4432901B2 (ja) | 2003-02-26 | 2010-03-17 | 萬有製薬株式会社 | ヘテロアリールカルバモイルベンゼン誘導体 |
JP4386035B2 (ja) | 2003-07-14 | 2009-12-16 | ソニー株式会社 | 情報提供システム、放送局特定サーバ、関連情報提供サーバ、コンテンツ配信サーバ、記録媒体販売サーバ及び情報提供方法 |
WO2005023766A1 (en) | 2003-09-11 | 2005-03-17 | Biocon Limited | Salt of atorvastatin with metformin |
MXPA06007667A (es) | 2004-01-06 | 2006-09-01 | Novo Nordisk As | Heteroaril-ureas y su uso como activadores de glucocinasa. |
CN1910166B (zh) * | 2004-01-06 | 2012-01-04 | 诺和诺德公司 | 杂芳基脲及其作为葡糖激酶活化剂的用途 |
EP1758611A2 (en) * | 2004-06-17 | 2007-03-07 | Novo Nordisk A/S | Use of liver-selective glucokinase activators |
WO2006110809A2 (en) | 2005-04-12 | 2006-10-19 | Elan Pharma International, Limited | Nanoparticulate lipase inhibitor formulations |
US20100028439A1 (en) | 2005-05-23 | 2010-02-04 | Elan Pharma International Limited | Nanoparticulate stabilized anti-hypertensive compositions |
ATE547396T1 (de) | 2005-07-08 | 2012-03-15 | Novo Nordisk As | Dicycloalkylcarbamoyl-harnstoffe als glucokinase- aktivatoren |
CN101258137A (zh) * | 2005-07-08 | 2008-09-03 | 诺沃-诺迪斯克有限公司 | 双环烷基脲葡糖激酶活化剂 |
WO2007006760A1 (en) | 2005-07-08 | 2007-01-18 | Novo Nordisk A/S | Dicycloalkyl urea glucokinase activators |
EP1904467B1 (en) | 2005-07-14 | 2013-05-01 | Novo Nordisk A/S | Urea glucokinase activators |
EP2091947A2 (en) | 2006-12-20 | 2009-08-26 | Takeda San Diego, Inc. | Glucokinase activators |
US8138185B2 (en) | 2007-01-09 | 2012-03-20 | Novo Nordisk A/S | Urea glucokinase activators |
WO2009140624A2 (en) | 2008-05-16 | 2009-11-19 | Takeda San Diego, Inc. | Glucokinase activators |
EP2305737A4 (en) | 2008-07-22 | 2015-03-04 | Kureha Corp | PROCESS FOR PRODUCING POLYARYLENE SULFIDE HAVING REDUCED HALOGEN TERMINAL GROUP CONTENT |
WO2010107610A1 (en) * | 2009-03-17 | 2010-09-23 | Merck Sharp & Dohme Corp. | Method for treatment of diabetes and related conditions with combination therapy and compositions containing such compounds |
KR20150046382A (ko) | 2009-04-16 | 2015-04-29 | 다이쇼 세이야꾸 가부시끼가이샤 | 제약 조성물 |
KR101190957B1 (ko) | 2009-08-25 | 2012-10-15 | 한올바이오파마주식회사 | 메트포르민 카페익산염, 그의 제조방법, 그를 포함하는 약학 조성물 및 그를 포함하는 복합제제 |
CA2799591C (en) * | 2010-05-26 | 2019-06-11 | Transtech Pharma, Inc. | Use of metformin in combination with a glucokinase activator and compositions comprising metformin and a glucokinase activator |
EP2392575A1 (en) * | 2010-06-04 | 2011-12-07 | LEK Pharmaceuticals d.d. | A novel synthetic approach to ß-aminobutyryl substituted compounds |
KR102371364B1 (ko) | 2012-05-17 | 2022-03-07 | 브이티브이 테라퓨틱스 엘엘씨 | 당뇨병 치료를 위한 글루코키나아제 활성화제 조성물 |
MX2015011109A (es) | 2013-03-04 | 2015-11-16 | Vtv Therapeutics Llc | Composiciones estables de activador de glucoquinasa. |
CN105188676A (zh) | 2013-03-04 | 2015-12-23 | Vtv治疗有限责任公司 | 包括葡糖激酶活化剂的固体组合物及其制备和使用方法 |
-
2013
- 2013-05-15 KR KR1020217006420A patent/KR102371364B1/ko active IP Right Grant
- 2013-05-15 WO PCT/US2013/041076 patent/WO2013173417A2/en active Application Filing
- 2013-05-15 ES ES13726933T patent/ES2878001T3/es active Active
- 2013-05-15 BR BR112014028622A patent/BR112014028622A2/pt not_active Application Discontinuation
- 2013-05-15 JP JP2015512779A patent/JP6234443B2/ja active Active
- 2013-05-15 MX MX2014013105A patent/MX360304B/es active IP Right Grant
- 2013-05-15 AU AU2013262895A patent/AU2013262895A1/en not_active Abandoned
- 2013-05-15 CA CA2872021A patent/CA2872021C/en active Active
- 2013-05-15 SG SG10201609644UA patent/SG10201609644UA/en unknown
- 2013-05-15 KR KR1020147035545A patent/KR20150013838A/ko active Application Filing
- 2013-05-15 EA EA201492109A patent/EA201492109A1/ru unknown
- 2013-05-15 EP EP13726933.8A patent/EP2849776B1/en active Active
- 2013-05-15 SG SG11201406987UA patent/SG11201406987UA/en unknown
- 2013-05-15 IN IN9554DEN2014 patent/IN2014DN09554A/en unknown
- 2013-05-15 CN CN201380024802.XA patent/CN104349790A/zh active Pending
- 2013-11-05 US US14/071,976 patent/US10004782B2/en active Active
-
2014
- 2014-11-03 IL IL235484A patent/IL235484A0/en unknown
-
2015
- 2015-03-31 HK HK15103235.2A patent/HK1202458A1/zh unknown
-
2017
- 2017-06-07 AU AU2017203835A patent/AU2017203835B2/en active Active
-
2018
- 2018-05-18 US US15/983,249 patent/US10588943B2/en active Active
-
2020
- 2020-01-16 US US16/744,956 patent/US10980861B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2017203835A1 (en) | 2017-06-22 |
CA2872021C (en) | 2022-08-16 |
WO2013173417A3 (en) | 2014-02-20 |
KR20150013838A (ko) | 2015-02-05 |
SG11201406987UA (en) | 2014-12-30 |
IL235484A0 (en) | 2014-12-31 |
EA201492109A1 (ru) | 2015-07-30 |
KR20210027547A (ko) | 2021-03-10 |
ES2878001T3 (es) | 2021-11-18 |
MX360304B (es) | 2018-10-29 |
JP6234443B2 (ja) | 2017-11-22 |
SG10201609644UA (en) | 2017-01-27 |
MX2014013105A (es) | 2015-04-08 |
CN104349790A (zh) | 2015-02-11 |
AU2017203835B2 (en) | 2018-11-22 |
JP2015517525A (ja) | 2015-06-22 |
CA2872021A1 (en) | 2013-11-21 |
AU2013262895A1 (en) | 2014-11-13 |
US20140066372A1 (en) | 2014-03-06 |
US10588943B2 (en) | 2020-03-17 |
KR102371364B1 (ko) | 2022-03-07 |
BR112014028622A2 (pt) | 2017-06-27 |
US20200138909A1 (en) | 2020-05-07 |
IN2014DN09554A (zh) | 2015-07-17 |
US20180311314A1 (en) | 2018-11-01 |
US10004782B2 (en) | 2018-06-26 |
EP2849776B1 (en) | 2021-04-21 |
WO2013173417A2 (en) | 2013-11-21 |
EP2849776A2 (en) | 2015-03-25 |
US10980861B2 (en) | 2021-04-20 |
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