HK120196A - Improvements in or relating to beta lactam production - Google Patents

Improvements in or relating to beta lactam production Download PDF

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Publication number
HK120196A
HK120196A HK120196A HK120196A HK120196A HK 120196 A HK120196 A HK 120196A HK 120196 A HK120196 A HK 120196A HK 120196 A HK120196 A HK 120196A HK 120196 A HK120196 A HK 120196A
Authority
HK
Hong Kong
Prior art keywords
alpha
aminoacyl
penicillin
desacetoxy
isolating
Prior art date
Application number
HK120196A
Other languages
English (en)
Inventor
Diago Jose
Ludescher Johannes
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HK120196A publication Critical patent/HK120196A/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK120196A 1990-01-22 1996-07-11 Improvements in or relating to beta lactam production HK120196A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT12790 1990-01-22

Publications (1)

Publication Number Publication Date
HK120196A true HK120196A (en) 1996-07-19

Family

ID=3482233

Family Applications (1)

Application Number Title Priority Date Filing Date
HK120196A HK120196A (en) 1990-01-22 1996-07-11 Improvements in or relating to beta lactam production

Country Status (12)

Country Link
US (1) US5840885A (https=)
EP (2) EP0976755A1 (https=)
JP (1) JPH089626B2 (https=)
KR (1) KR0177176B1 (https=)
AT (1) ATE256687T1 (https=)
DE (1) DE69133346T2 (https=)
ES (1) ES2213137T3 (https=)
GB (1) GB2240102B (https=)
HK (1) HK120196A (https=)
HU (1) HU221200B1 (https=)
PL (2) PL167136B1 (https=)
TW (1) TW265344B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9115203D0 (en) * 1991-07-15 1991-08-28 Biochemie Gmbh Improvements in or relating to beta lactam production
ES2050621B1 (es) * 1992-11-06 1994-12-16 Antibioticos Sa Un procedimiento mejorado para la preparacion de 6-*-aminopenicilinas.
CN1035435C (zh) * 1993-03-16 1997-07-16 沈阳医药工业研究所 半合成青霉素缩合新工艺
CN1034177C (zh) * 1993-12-02 1997-03-05 山东新华制药厂 头孢氨苄的制备方法
GB9423459D0 (en) * 1994-11-21 1995-01-11 Biochemie Gmbh Silylation process
GB9513115D0 (en) * 1995-06-28 1995-08-30 Biochemie Sa Organic compounds
US5908929A (en) * 1996-12-05 1999-06-01 Vitara Chemicals Limited Process for the manufacture of the antibiotic 7-(D-α-amino-α-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid (cephalexin) and pharmaceutically acceptable salts thereof
EP0953569A1 (en) * 1998-04-29 1999-11-03 Gist-Brocades B.V. Preparation of beta-lactam antibiotics in the presence of urea or amide
WO2004092177A1 (en) 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolopyrazines and methods of making and using the same
WO2004092173A2 (en) 2003-04-09 2004-10-28 Biogen Idec Ma Inc. A2a adenosine receptor antagonists
WO2004092170A2 (en) 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagon ists
KR101420451B1 (ko) * 2006-05-19 2014-07-16 디에스엠 시노켐 파마슈티칼스 네덜란드 비.브이. 세파드록실의 결정화 방법

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB991586A (en) * 1963-02-28 1965-05-12 Beecham Res Lab Process for the preparation of penicillins
US4123611A (en) * 1970-10-21 1978-10-31 President Of Osaka University N-protected amino compounds
JPS5343597B1 (https=) * 1970-12-25 1978-11-21
IT1043957B (it) * 1970-12-31 1980-02-29 Lorenzini Sas Inst Biochim Processo per la preparazione della forma anidra dell acido 6, d, meno alfa aminofenilacetamido penicillanico
JPS4826985A (https=) * 1971-08-12 1973-04-09
GB1459999A (en) * 1972-12-27 1976-12-31 Novo Industri As Penicillin and cephalosporin intermediates
US3904606A (en) * 1973-01-12 1975-09-09 Upjohn Co Process for preparing optically active 6-(' -amino-acetamido)penicillanic acids and 7-(' -aminoacetamido) cephalosporanic acids
FR2220531A1 (en) * 1973-03-06 1974-10-04 Aries Robert Synthesis of penicillins from 6-amino penicillanic acid - by acylation with acid chlorides using hexamethylphosphotriamide as solvent
YU36733B (en) * 1973-10-26 1984-08-31 Krka Novo Mesto Process for preparing pure anhydrous 6-zd-(-)-alfa-aminophenylacetamidoc-penicillanic acid
GB1494902A (en) * 1974-05-09 1977-12-14 Glaxo Lab Ltd Penicillins
GB1459807A (en) * 1975-05-27 1976-12-31 Proter Spa Process for the production of 7-d-a-amino-phenyl-acetamido-3- desacetoxy-cephalosporanic acid
DE2613172A1 (de) * 1976-03-27 1977-10-06 Bayer Ag Verfahren zur herstellung von penicillinen und cephalosporinen
GB1532672A (en) * 1976-07-20 1978-11-15 Bristol Myers Co Process for the preparation of amoxicillin trihydrate
YU40474B (en) * 1977-04-04 1986-02-28 Glenika Process for obtaining amoxicillin
ES459494A1 (es) * 1977-06-04 1978-05-01 Palomo Coll A Luis Procedimiento de preparacion de hidrox-alfa-aminobencilpeni-cilina.
GB2001985B (en) * 1977-08-05 1982-07-07 Lark Spa Process for the preparation of penicillanic and cephalosporanic acid derivatives
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
JPS5459296A (en) * 1977-10-14 1979-05-12 Toshin Chemical Co Production of alphaaaminoo paraahydroxybenzylpeniciline
DE2817228A1 (de) * 1978-04-20 1979-10-31 Bayer Ag Verfahren zur herstellung halbsynthetischer beta-lactamantibiotika
GB2034695B (en) * 1978-10-06 1982-10-27 Glaxo Group Ltd Acylation of 6-apa via silyl intermediates
CA1125745A (en) * 1978-11-20 1982-06-15 Joseph Kaspi PROCESS FOR PREPARING .beta.-LACTAM ANTIBIOTICS
US4248780A (en) * 1979-08-21 1981-02-03 Canada Packers Limited Process for preparing ampicillin
IT1126544B (it) * 1979-12-07 1986-05-21 Dobfar Spa Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico
IT1180207B (it) * 1984-07-30 1987-09-23 Istituto Biochimico Italiano Procedimento per la preparazione, con resa e purezza elevate, di antibiotici beta-lattamici
US5142043A (en) * 1990-05-10 1992-08-25 Biocraft Laboratories, Inc. Process for preparing cephalexin monohydrate

Also Published As

Publication number Publication date
EP0976755A1 (en) 2000-02-02
KR0177176B1 (ko) 1999-03-20
GB2240102A (en) 1991-07-24
JPH0597865A (ja) 1993-04-20
ES2213137T3 (es) 2004-08-16
US5840885A (en) 1998-11-24
HU221200B1 (en) 2002-08-28
JPH089626B2 (ja) 1996-01-31
ATE256687T1 (de) 2004-01-15
DE69133346D1 (de) 2004-01-29
DE69133346T2 (de) 2004-10-07
HU910054D0 (en) 1991-08-28
PL288790A1 (en) 1991-12-16
KR910014381A (ko) 1991-08-31
GB2240102B (en) 1993-10-20
GB9100404D0 (en) 1991-02-20
PL167748B1 (pl) 1995-10-31
EP0439096A2 (en) 1991-07-31
PL167136B1 (pl) 1995-07-31
EP0439096B1 (en) 2003-12-17
TW265344B (https=) 1995-12-11
EP0439096A3 (en) 1992-06-10

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Legal Events

Date Code Title Description
PF Patent in force
AS Change of ownership

Owner name: SANDOZ AG

Free format text: FORMER OWNER(S): SANDOZ GMBH

CHPA Change of a particular in the register (except of change of ownership)
PE Patent expired

Effective date: 20110108