HK1199873A1 - 激酶抑制劑 - Google Patents

激酶抑制劑

Info

Publication number
HK1199873A1
HK1199873A1 HK15100163.4A HK15100163A HK1199873A1 HK 1199873 A1 HK1199873 A1 HK 1199873A1 HK 15100163 A HK15100163 A HK 15100163A HK 1199873 A1 HK1199873 A1 HK 1199873A1
Authority
HK
Hong Kong
Prior art keywords
kinase inhibitors
kinase
inhibitors
Prior art date
Application number
HK15100163.4A
Other languages
English (en)
Inventor
．范尼爾
‧雷伊
‧阿爾卡拉斯
‧潘查爾
‧詹寧斯
‧阿爾馬尼
‧克裡德蘭德
‧赫爾利
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of HK1199873A1 publication Critical patent/HK1199873A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK15100163.4A 2011-12-09 2015-01-07 激酶抑制劑 HK1199873A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11192894 2011-12-09
EP12187932 2012-10-10
PCT/EP2012/074450 WO2013083606A1 (en) 2011-12-09 2012-12-05 Kinase inhibitors

Publications (1)

Publication Number Publication Date
HK1199873A1 true HK1199873A1 (zh) 2015-07-24

Family

ID=47469888

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15100163.4A HK1199873A1 (zh) 2011-12-09 2015-01-07 激酶抑制劑

Country Status (19)

Country Link
US (2) US8835431B2 (zh)
EP (1) EP2788348B1 (zh)
JP (1) JP6145849B2 (zh)
KR (1) KR20140105459A (zh)
CN (1) CN103974953B (zh)
AR (1) AR089113A1 (zh)
AU (1) AU2012347352B2 (zh)
BR (1) BR112014013177A2 (zh)
CA (1) CA2860479A1 (zh)
HK (1) HK1199873A1 (zh)
IL (1) IL232959A (zh)
MX (1) MX351958B (zh)
MY (1) MY167216A (zh)
PH (1) PH12014501278A1 (zh)
RU (1) RU2623734C9 (zh)
SG (2) SG10201604656YA (zh)
TW (1) TWI568732B (zh)
WO (1) WO2013083606A1 (zh)
ZA (1) ZA201404157B (zh)

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MY167216A (en) * 2011-12-09 2018-08-14 Chiesi Farm Spa Kinase inhibitors
AU2012347350C1 (en) 2011-12-09 2017-01-19 Chiesi Farmaceutici S.P.A. Kinase inhibitors
BR112014013178A2 (pt) * 2011-12-09 2017-06-13 Chiesi Farm Spa composto, composição farmacêutica e uso de um composto
BR112015029970A2 (pt) 2013-06-06 2017-07-25 Chiesi Farm Spa inibidores de cinase
WO2017108737A1 (en) * 2015-12-23 2017-06-29 Chiesi Farmaceutici S.P.A. 1-(3-tert-butyl-phenyl)-3-(4-([1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro- naphthalen-1-yl)-urea derivatives and their use as p38 mapk inhibitors
US10364245B2 (en) * 2017-06-07 2019-07-30 Chiesi Farmaceutici S.P.A. Kinase inhibitors
WO2019071147A1 (en) 2017-10-05 2019-04-11 Fulcrum Therapeutics, Inc. INHIBITORS OF KINASE P38 REDUCING EXPRESSION OF DUX4 GENE AND DOWNSTREAM GENES FOR THE TREATMENT OF FSHD
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
CN108424372B (zh) * 2018-05-11 2021-08-10 浙江华贝药业有限责任公司 2，2，2-三氟-n-[(s)-4-羰基四氢萘-1-基]-乙酰胺的纯化工艺
RU2676692C1 (ru) * 2018-08-01 2019-01-10 Российская Федерация, От Имени Которой Выступает Министерство Промышленности И Торговли Российской Федерации Способ получения n-фенил-2-нафтиламина
JP7323926B2 (ja) 2019-10-31 2023-08-09 株式会社タカゾノ 巻回体
JP7333062B2 (ja) 2019-10-31 2023-08-24 株式会社タカゾノ 巻回体
JP7301362B2 (ja) 2019-10-31 2023-07-03 株式会社タカゾノ 芯体

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US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
YU25500A (sh) 1999-05-11 2003-08-29 Pfizer Products Inc. Postupak za sintezu analoga nukleozida
DE60024830T2 (de) 1999-07-09 2006-06-14 Boehringer Ingelheim Pharma Verfahren zur herstellung heteroarylsubstituierter ureaverbindungen
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WO2005018624A2 (en) * 2003-08-22 2005-03-03 Boehringer Ingelheim Pharmaceuticals, Inc. Methods of treating copd and pulmonary hypertension
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WO2006009741A1 (en) 2004-06-23 2006-01-26 Eli Lilly And Company Kinase inhibitors
EP1609789A1 (en) 2004-06-23 2005-12-28 Eli Lilly And Company Ureido-pyrazole derivatives and their use as kinase inhibitors
NZ552868A (en) 2004-08-12 2009-07-31 Pfizer Triazolopyridinylsulfanyl derivatives as P38 MAP kinase inhibitors
JP2008509985A (ja) 2004-08-18 2008-04-03 ファルマシア アンド アップジョン カンパニー リミテッド ライアビリティ カンパニー 炎症治療用の新規トリアゾロピリジン化合物
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WO2010108058A2 (en) 2009-03-20 2010-09-23 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Small molecule inhibitors of dusp6 and uses therefor
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GB201005589D0 (en) * 2010-04-01 2010-05-19 Respivert Ltd Novel compounds
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GB201009731D0 (en) * 2010-06-10 2010-07-21 Pulmagen Therapeutics Inflamma Kinase inhibitors
AU2012347350C1 (en) * 2011-12-09 2017-01-19 Chiesi Farmaceutici S.P.A. Kinase inhibitors
BR112014013178A2 (pt) * 2011-12-09 2017-06-13 Chiesi Farm Spa composto, composição farmacêutica e uso de um composto
MY167216A (en) * 2011-12-09 2018-08-14 Chiesi Farm Spa Kinase inhibitors

Also Published As

Publication number Publication date
US20140343055A1 (en) 2014-11-20
US8835431B2 (en) 2014-09-16
US20130150361A1 (en) 2013-06-13
CN103974953B (zh) 2016-06-29
PH12014501278B1 (en) 2014-09-08
RU2014123031A (ru) 2016-01-27
IL232959A0 (en) 2014-08-03
KR20140105459A (ko) 2014-09-01
BR112014013177A2 (pt) 2017-06-13
RU2623734C2 (ru) 2017-06-29
WO2013083606A1 (en) 2013-06-13
EP2788348B1 (en) 2016-10-19
JP6145849B2 (ja) 2017-06-14
CN103974953A (zh) 2014-08-06
US9029373B2 (en) 2015-05-12
TW201331200A (zh) 2013-08-01
ZA201404157B (en) 2015-12-23
IL232959A (en) 2016-11-30
MY167216A (en) 2018-08-14
RU2623734C9 (ru) 2017-09-18
CA2860479A1 (en) 2013-06-13
AR089113A1 (es) 2014-07-30
MX351958B (es) 2017-11-06
AU2012347352A1 (en) 2014-07-03
PH12014501278A1 (en) 2014-09-08
TWI568732B (zh) 2017-02-01
MX2014006629A (es) 2014-07-09
AU2012347352B2 (en) 2016-12-15
JP2015502948A (ja) 2015-01-29
EP2788348A1 (en) 2014-10-15
SG10201604656YA (en) 2016-07-28
SG11201402986RA (en) 2014-12-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20201208