HK1199843A1 - Oral spray formulations and methods for administration of sildenafil - Google Patents

Oral spray formulations and methods for administration of sildenafil

Info

Publication number
HK1199843A1
HK1199843A1 HK15100438.3A HK15100438A HK1199843A1 HK 1199843 A1 HK1199843 A1 HK 1199843A1 HK 15100438 A HK15100438 A HK 15100438A HK 1199843 A1 HK1199843 A1 HK 1199843A1
Authority
HK
Hong Kong
Prior art keywords
sildenafil
administration
methods
spray formulations
oral spray
Prior art date
Application number
HK15100438.3A
Other languages
English (en)
Chinese (zh)
Inventor
David Bergstrom
Foye Opawale
Original Assignee
Suda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suda Ltd filed Critical Suda Ltd
Publication of HK1199843A1 publication Critical patent/HK1199843A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK15100438.3A 2011-12-05 2015-01-15 Oral spray formulations and methods for administration of sildenafil HK1199843A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161566879P 2011-12-05 2011-12-05
PCT/US2012/067763 WO2013085904A1 (en) 2011-12-05 2012-12-04 Oral spray formulations and methods for administration of sildenafil

Publications (1)

Publication Number Publication Date
HK1199843A1 true HK1199843A1 (en) 2015-07-24

Family

ID=47430090

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15100438.3A HK1199843A1 (en) 2011-12-05 2015-01-15 Oral spray formulations and methods for administration of sildenafil

Country Status (14)

Country Link
US (1) US9186321B2 (es)
EP (1) EP2787967B1 (es)
JP (1) JP6047174B2 (es)
KR (1) KR20140117360A (es)
CN (1) CN104822368B (es)
AU (1) AU2012347997B2 (es)
BR (1) BR112014013650A2 (es)
CA (1) CA2858364C (es)
HK (1) HK1199843A1 (es)
IL (1) IL232970A0 (es)
RU (1) RU2611403C1 (es)
SG (1) SG11201402938RA (es)
WO (1) WO2013085904A1 (es)
ZA (1) ZA201404091B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9370518B2 (en) * 2013-11-08 2016-06-21 Insys Development Company, Inc. Sildenafil sublingual spray formulation
NO2723977T3 (es) 2014-03-19 2018-03-10
CA2981615A1 (en) * 2015-04-03 2016-10-06 Insys Development Company, Inc. Sildenafil sublingual spray formulations
US10111833B2 (en) 2015-04-03 2018-10-30 Insys Development Company, Inc. Sildenafil sublingual spray formulations
BR102015020720A2 (pt) * 2015-08-27 2017-03-01 Henrique Leonardo Pereira Luis composição hidrofíilica atóxica, bioidêntica e biodegradável à base de partículas micronizadas de acido hialurônico, com propriedades mucoadesivas e carreadoras via transmucosa aglutinadas por bioengenharia a um ipde5, para tratamento de disfunção erétil, com aplicação em sistema de spray de aerossol sublingual
WO2018070971A1 (ru) * 2016-10-10 2018-04-19 Товарыство З Обмэжэною Видповидальнистю Науково-Выробныча Фирма "Микрохим" Фармацевтическая композиция в форме оромукозного спрея для лечения эректильной дисфункции и легочной артериальной гипертензии
CN109996547A (zh) * 2016-10-31 2019-07-09 苏达有限公司 粘膜活性剂递送
JP2023502004A (ja) * 2019-11-07 2023-01-20 ノヴォ ノルディスク アー／エス Ｇｌｐ－１作動薬、ｓｇｌｔ２阻害剤、およびｎ－（８－（２－ヒドロキシベンゾイル）アミノ）カプリル酸の塩を含む固形組成物
CN111110633B (zh) * 2020-01-21 2022-12-02 合肥医工医药股份有限公司 一种他达拉非喷雾剂及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030082107A1 (en) * 1997-10-01 2003-05-01 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer
US20030077229A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
DE19834506A1 (de) 1998-07-31 2000-02-03 Hexal Ag Transmucosales therapeutisches System zur Anwendung von Sildenafil
JP2002533380A (ja) * 1998-12-23 2002-10-08 アルザ・コーポレーション 多孔性粒子を含む剤形
IL139456A0 (en) * 1999-11-08 2001-11-25 Pfizer Compounds for the treatment of female sexual dysfunction
AU3048501A (en) 1999-11-18 2001-05-30 Natco Pharma Limited An improved pharmaceutical composition for treating male erectile dysfunction
CN1277021A (zh) * 2000-06-20 2000-12-20 王建华 一种治疗阳痿病的喷雾剂药物及其制备方法
DE10248601B4 (de) * 2002-10-17 2006-05-24 Goldstein, Naum, Dr.habil.nat. Pharmazeutisches Mittel zur endonasalen Applikation bei der Behandlung von Krankheiten und Störungen des zentralen Nervensystems
WO2005077374A1 (en) 2004-02-06 2005-08-25 Becton, Dickinson And Company Formulations of phosphodiesterase 5 inhibitors and methods of use
US7554270B2 (en) * 2004-05-17 2009-06-30 Tokyo Ohka Kogyo Co., Ltd. Composition for dielectric of plasma display panel, laminate for dielectric, and method for forming the dielectric
CN101014321A (zh) * 2004-08-23 2007-08-08 曼金德公司 5型磷酸二酯酶抑制剂的肺部给予
EP1898879A1 (en) 2005-06-23 2008-03-19 Schering Corporation Rapidly absorbing oral formulations of pde5 inhibitors
AU2007204208A1 (en) * 2006-01-11 2007-07-19 Astrazeneca Ab Morpholino pyrimidine derivatives and their use in therapy
US20090317461A1 (en) * 2006-08-02 2009-12-24 Wm. Wrigley Jr. Company Oral compositions effective for the treatment of oral cavity malodor associated with the consumption of odor-causing compounds
JP5686978B2 (ja) * 2009-03-18 2015-03-18 第一三共ヘルスケア株式会社 シルデナフィルクエン酸塩含有内服液剤及びその液剤含有容器

Also Published As

Publication number Publication date
JP2015500285A (ja) 2015-01-05
US9186321B2 (en) 2015-11-17
SG11201402938RA (en) 2014-07-30
AU2012347997B2 (en) 2017-07-20
CA2858364A1 (en) 2013-06-13
EP2787967B1 (en) 2018-10-31
AU2012347997A1 (en) 2014-07-03
US20150051216A1 (en) 2015-02-19
CN104822368A (zh) 2015-08-05
JP6047174B2 (ja) 2016-12-21
WO2013085904A1 (en) 2013-06-13
BR112014013650A2 (pt) 2017-07-04
NZ625922A (en) 2015-05-29
EP2787967A1 (en) 2014-10-15
RU2611403C1 (ru) 2017-02-21
CA2858364C (en) 2018-07-24
KR20140117360A (ko) 2014-10-07
CN104822368B (zh) 2019-01-11
ZA201404091B (en) 2017-11-29
IL232970A0 (en) 2014-08-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20221202