HK1199262A1 - Methods and systems for forming boronic acids and intermediates thereof - Google Patents

Methods and systems for forming boronic acids and intermediates thereof

Info

Publication number
HK1199262A1
HK1199262A1 HK14112835.8A HK14112835A HK1199262A1 HK 1199262 A1 HK1199262 A1 HK 1199262A1 HK 14112835 A HK14112835 A HK 14112835A HK 1199262 A1 HK1199262 A1 HK 1199262A1
Authority
HK
Hong Kong
Prior art keywords
intermediates
systems
methods
boronic acids
forming boronic
Prior art date
Application number
HK14112835.8A
Other languages
English (en)
Chinese (zh)
Inventor
Catherine A Menning
D Wayne Blaylock
Mark V M Emonds
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of HK1199262A1 publication Critical patent/HK1199262A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/24—Stationary reactors without moving elements inside
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/02—Lithium compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00002—Chemical plants
    • B01J2219/00004—Scale aspects
    • B01J2219/00011—Laboratory-scale plants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00002—Chemical plants
    • B01J2219/00027—Process aspects
    • B01J2219/0004—Processes in series
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00051—Controlling the temperature
    • B01J2219/00074—Controlling the temperature by indirect heating or cooling employing heat exchange fluids
    • B01J2219/00087—Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements outside the reactor
    • B01J2219/00094—Jackets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00051—Controlling the temperature
    • B01J2219/00074—Controlling the temperature by indirect heating or cooling employing heat exchange fluids
    • B01J2219/00087—Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements outside the reactor
    • B01J2219/00099—Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements outside the reactor the reactor being immersed in the heat exchange medium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/0059—Sequential processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00788—Three-dimensional assemblies, i.e. the reactor comprising a form other than a stack of plates
    • B01J2219/00792—One or more tube-shaped elements
    • B01J2219/00795—Spiral-shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00801—Means to assemble
    • B01J2219/0081—Plurality of modules
    • B01J2219/00813—Fluidic connections
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00822—Metal
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00858—Aspects relating to the size of the reactor
    • B01J2219/0086—Dimensions of the flow channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00867—Microreactors placed in series, on the same or on different supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00873—Heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00891—Feeding or evacuation
    • B01J2219/00894—More than two inlets

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
HK14112835.8A 2011-09-14 2014-12-23 Methods and systems for forming boronic acids and intermediates thereof HK1199262A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161534768P 2011-09-14 2011-09-14
PCT/US2012/055605 WO2013040479A1 (en) 2011-09-14 2012-09-14 Methods and systems for forming boronic acids and intermediates thereof

Publications (1)

Publication Number Publication Date
HK1199262A1 true HK1199262A1 (en) 2015-06-26

Family

ID=47830429

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14112835.8A HK1199262A1 (en) 2011-09-14 2014-12-23 Methods and systems for forming boronic acids and intermediates thereof

Country Status (14)

Country Link
US (1) US9145428B2 (da)
EP (1) EP2755980B1 (da)
JP (3) JP6425543B2 (da)
KR (2) KR102062323B1 (da)
CN (1) CN103827124B (da)
CA (1) CA2847858A1 (da)
CO (1) CO6930354A2 (da)
DK (1) DK2755980T3 (da)
HK (1) HK1199262A1 (da)
IL (1) IL231391A (da)
MX (1) MX2014003064A (da)
PL (1) PL2755980T3 (da)
RU (1) RU2607941C2 (da)
WO (1) WO2013040479A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3012145B1 (fr) * 2013-10-18 2015-12-18 Yriel Procede continu de preparation d'acides boroniques et de leurs derives
US9771380B2 (en) * 2014-06-09 2017-09-26 University Of Oregon Gold nanoparticles and methods of making and using gold nanoparticles
CN105056842B (zh) * 2015-07-23 2017-12-15 厦门大学 一种反应装置及其在合成硼酸酯中的应用
CN106422985A (zh) * 2016-11-30 2017-02-22 南京睿宇物联网科技有限公司 用于安全添加叔丁基锂至反应器的反应系统
JOP20190188A1 (ar) 2017-02-01 2019-08-01 Rempex Pharmaceuticals Inc جهاز وعملية تدفق مستمرة لإنتاج مشتق حمض بورونيك
EP4121414A1 (en) 2020-03-18 2023-01-25 Corteva Agriscience LLC Improved synthesis of 4-amino-6-(heterocyclic)picolinates
EP4121416A1 (en) 2020-03-18 2023-01-25 Corteva Agriscience LLC Improved synthesis of 6-aryl-4-aminopicolinates
AU2022210427A1 (en) 2021-01-21 2023-06-15 Corteva Agriscience Llc Processes related to formation of n-(3-chloro-1-(pyridin-3-yl)-1h-pyrazol-4-yl)-2-(methylsulfonyl)propanamide
CN112979688B (zh) * 2021-05-20 2022-02-01 凯莱英医药集团（天津）股份有限公司 2-氟-4-三氟甲基苯硼酸的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19858856A1 (de) * 1998-12-19 2000-06-21 Merck Patent Gmbh Verfahren zur Herstellung von Arylmetallverbindungen und deren Umsetzung mit Elektrophilen
EP1345603A4 (en) * 2000-12-20 2004-09-08 Merck & Co Inc P38 KINASE INHIBITORS (HALO-BENZO CARBONYL) HETEROCYCLO- FUSIONNES PHENYL
DE10110051C2 (de) * 2001-03-02 2003-07-03 Clariant Gmbh Verfahren zur Herstellung von Boron- und Borinsäuren
DE10139664A1 (de) * 2001-08-11 2003-02-20 Clariant Gmbh Verfahren zur Herstellung von Aryl- und Alkyl-Bor-Verbindungen in Mikroreaktoren
DE10150615A1 (de) * 2001-10-12 2003-04-30 Clariant Gmbh Verfahren zur metallorganischen Herstellung organischer Zwischenprodukte
AU2003225072A1 (en) * 2002-04-19 2003-11-03 Smithkline Beecham Corporation Novel compounds
JP4639042B2 (ja) * 2003-09-29 2011-02-23 富士フイルムファインケミカルズ株式会社 ハロゲン−リチウム交換反応を用いる有機化合物の製造法
FR2864083B1 (fr) * 2003-12-18 2007-04-13 Galderma Res & Dev Nouveaux derives d'acides phenyl-boroniques et leurs procedes de preparation.
DE102005037547A1 (de) 2005-08-09 2007-02-15 Basf Ag Verfahren zur Herstellung von Arylboronsäureestern
CA2626103C (en) * 2006-01-13 2013-07-30 Dow Agrosciences Llc 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides
AU2007204887B2 (en) 2006-01-13 2011-06-23 Corteva Agriscience Llc 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides
US7998418B1 (en) * 2006-06-01 2011-08-16 Nanotek, Llc Evaporator and concentrator in reactor and loading system
CA2695644C (en) * 2007-08-30 2015-11-24 Dow Agrosciences Llc 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides
JP5501979B2 (ja) * 2008-01-11 2014-05-28 ダウ アグロサイエンシィズ エルエルシー １−フルオロ−２−置換−３−クロロベンゼンの選択的脱プロトン化及び官能化の方法
EP2371831B1 (en) * 2008-12-25 2016-09-07 Nippon Soda Co., Ltd. Process for producing organolithium compound and process for producing substituted aromatic compound
SG11201401032YA (en) * 2011-10-26 2014-07-30 Pfizer Ltd (4-phenylimidazol-2-yl) ethylamine derivatives useful as sodium channel modulators

Also Published As

Publication number Publication date
CO6930354A2 (es) 2014-04-28
CA2847858A1 (en) 2013-03-21
KR20190112820A (ko) 2019-10-07
JP6456907B2 (ja) 2019-01-23
EP2755980A1 (en) 2014-07-23
JP2019038827A (ja) 2019-03-14
KR102062323B1 (ko) 2020-01-03
CN103827124B (zh) 2017-06-06
WO2013040479A1 (en) 2013-03-21
IL231391A (en) 2016-12-29
DK2755980T3 (da) 2020-01-27
IL231391A0 (en) 2014-04-30
JP2017095472A (ja) 2017-06-01
MX2014003064A (es) 2014-05-07
NZ622139A (en) 2015-05-29
JP2014530193A (ja) 2014-11-17
PL2755980T3 (pl) 2020-05-18
KR20140061505A (ko) 2014-05-21
EP2755980A4 (en) 2015-06-03
RU2014114533A (ru) 2015-10-20
JP6425543B2 (ja) 2018-11-21
US20130066115A1 (en) 2013-03-14
US9145428B2 (en) 2015-09-29
CN103827124A (zh) 2014-05-28
RU2607941C2 (ru) 2017-01-11
EP2755980B1 (en) 2019-10-30

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