HK1188993A1 - 製備 -鹵代- -硝基咪唑化合物的方法 - Google Patents

製備 -鹵代- -硝基咪唑化合物的方法

Info

Publication number
HK1188993A1
HK1188993A1 HK14102050.7A HK14102050A HK1188993A1 HK 1188993 A1 HK1188993 A1 HK 1188993A1 HK 14102050 A HK14102050 A HK 14102050A HK 1188993 A1 HK1188993 A1 HK 1188993A1
Authority
HK
Hong Kong
Prior art keywords
halo
preparing
nitroimidazole compound
nitroimidazole
compound
Prior art date
Application number
HK14102050.7A
Other languages
English (en)
Inventor
Fumitaka Goto
Noriaki Takemura
Tadaaki Otani
Takeshi Hasegawa
Hidetsugu Tsubouchi
Naoto Utsumi
Shigekazu Fujita
Hideaki Kuroda
Takuya Shitsuta
Hirofumi Sasaki
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of HK1188993A1 publication Critical patent/HK1188993A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
HK14102050.7A 2002-10-15 2014-03-03 製備 -鹵代- -硝基咪唑化合物的方法 HK1188993A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002299896 2002-10-15
JP2003037914 2003-02-17

Publications (1)

Publication Number Publication Date
HK1188993A1 true HK1188993A1 (zh) 2014-05-23

Family

ID=32109445

Family Applications (2)

Application Number Title Priority Date Filing Date
HK06103740A HK1083830A1 (en) 2002-10-15 2006-03-24 1-Substituted 4-nitroimidazole compound and process for producing the same
HK14102050.7A HK1188993A1 (zh) 2002-10-15 2014-03-03 製備 -鹵代- -硝基咪唑化合物的方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK06103740A HK1083830A1 (en) 2002-10-15 2006-03-24 1-Substituted 4-nitroimidazole compound and process for producing the same

Country Status (17)

Country Link
US (4) US7368579B2 (zh)
EP (2) EP2644599B1 (zh)
JP (1) JP5014315B2 (zh)
KR (1) KR100655670B1 (zh)
AR (1) AR041605A1 (zh)
AU (1) AU2003301282B2 (zh)
BR (1) BR0313566A (zh)
CA (1) CA2494710C (zh)
EG (1) EG24885A (zh)
ES (1) ES2526892T3 (zh)
HK (2) HK1083830A1 (zh)
MX (1) MXPA05002414A (zh)
MY (1) MY145079A (zh)
PL (1) PL375103A1 (zh)
RU (1) RU2324682C2 (zh)
TW (2) TWI331607B (zh)
WO (1) WO2004035547A1 (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7368579B2 (en) * 2002-10-15 2008-05-06 Otsuka Pharmaceutical Co., Ltd. 1-substituted-4-nitroimidazole compound and process for producing the same
PL1678185T3 (pl) * 2003-10-31 2009-04-30 Otsuka Pharma Co Ltd Związki 2,3-dihydro-6-nitroimidazo[2,1-B]oksazolu do leczenia gruźlicy
TWI300409B (en) 2004-02-18 2008-09-01 Otsuka Pharma Co Ltd Method for producing 4-nitroimidazole compound
TW200624422A (en) * 2004-09-27 2006-07-16 Otsuka Pharma Co Ltd Process for production of 2-chloro-4-nitroimidazole
CN100338039C (zh) * 2004-11-29 2007-09-19 南京圣和药业有限公司 奥硝唑光学对映体的制备及纯化方法
MX2008001210A (es) * 2005-07-28 2008-03-24 Otsuka Pharma Co Ltd Composicion farmaceutica que comprende derivados de 2,3-dihidro-6-nitroimidazo{2,1-b]oxazol.
AR070301A1 (es) * 2007-05-08 2010-03-31 Otsuka Pharma Co Ltd Compuesto epoxi y metodo para producir el mismo
WO2010021409A1 (en) * 2008-08-21 2010-02-25 Dynamit Nobel Gmbh Explosivstoff - Und Systemtechnik Methods for the production of 2-halo-4-nitroimidazole and intermediates thereof
TW201200523A (en) 2010-01-29 2012-01-01 Otsuka Pharma Co Ltd Synthetic intermediate of oxazole compound and method for producing the same
US9572809B2 (en) 2012-07-18 2017-02-21 Spero Trinem, Inc. Combination therapy to treat Mycobacterium diseases
CN103396369B (zh) * 2013-08-14 2016-03-23 盐城工学院 一种制备2-氯-4-硝基咪唑的方法
RU2019136972A (ru) 2017-04-26 2021-05-26 Басф Се Замещенные сукцинимидные производные в качестве пестицидов
EP3696177A1 (en) 2019-02-12 2020-08-19 Basf Se Heterocyclic compounds for the control of invertebrate pests
WO2020202205A1 (en) * 2019-04-01 2020-10-08 Council Of Scientific And Industrial Research Process for the preparation of derivatives of 1,1-dialkylethane-1,2-diols as useful intermediates
US11958818B2 (en) 2019-05-01 2024-04-16 Boehringer Ingelheim International Gmbh (R)-(2-methyloxiran-2-yl)methyl 4-bromobenzenesulfonate

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341548A (en) * 1964-04-29 1967-09-12 Hoffmann La Roche Nitroimidazoles and their preparation
US3435049A (en) * 1965-05-19 1969-03-25 Hoffmann La Roche Nitroimidazole derivatives
DE2414280C2 (de) * 1974-03-25 1981-12-17 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 1-Methyl-5-nitroimidazolen
US4183941A (en) * 1978-08-21 1980-01-15 John R. A. Simoons Treatment of rheumatoid arthritis and related diseases
IL88943A (en) * 1988-01-15 1994-05-30 Rhone Poulenc Sante Process for the preparation of 1-alkyl-5-nitroimidazoles
US5344937A (en) * 1993-04-20 1994-09-06 Eli Lilly And Company Alkyl substituted nitroimidazole acetic acids
US5668127A (en) 1995-06-26 1997-09-16 Pathogenesis Corporation Nitroimidazole antibacterial compounds and methods of use thereof
AR041198A1 (es) * 2002-10-11 2005-05-04 Otsuka Pharma Co Ltd Compuesto 2,3-dihidro-6-nitroimidazo[2,1-b] oxaxol, y composiciones farmaceuticas que lo contienen
US7368579B2 (en) * 2002-10-15 2008-05-06 Otsuka Pharmaceutical Co., Ltd. 1-substituted-4-nitroimidazole compound and process for producing the same
TWI300409B (en) * 2004-02-18 2008-09-01 Otsuka Pharma Co Ltd Method for producing 4-nitroimidazole compound

Also Published As

Publication number Publication date
US8129544B2 (en) 2012-03-06
ES2526892T3 (es) 2015-01-16
AU2003301282A1 (en) 2004-05-04
TW200838855A (en) 2008-10-01
US20080097107A1 (en) 2008-04-24
PL375103A1 (en) 2005-11-28
RU2005114534A (ru) 2006-01-20
CA2494710A1 (en) 2004-04-29
AU2003301282B2 (en) 2009-04-30
US20120130082A1 (en) 2012-05-24
JP5014315B2 (ja) 2012-08-29
EP1553088A1 (en) 2005-07-13
US20080200689A1 (en) 2008-08-21
WO2004035547A1 (ja) 2004-04-29
US7368579B2 (en) 2008-05-06
KR100655670B1 (ko) 2007-02-28
EP1553088A4 (en) 2011-03-02
RU2324682C2 (ru) 2008-05-20
US7807843B2 (en) 2010-10-05
US20060079697A1 (en) 2006-04-13
BR0313566A (pt) 2005-06-21
EP2644599A1 (en) 2013-10-02
EG24885A (en) 2010-12-06
AR041605A1 (es) 2005-05-26
MXPA05002414A (es) 2005-06-22
EP2644599B1 (en) 2014-12-10
JP2009102329A (ja) 2009-05-14
TW200410943A (en) 2004-07-01
HK1083830A1 (en) 2006-08-11
CA2494710C (en) 2011-05-03
TWI331607B (en) 2010-10-11
MY145079A (en) 2011-12-15
KR20050046013A (ko) 2005-05-17

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20181014