HK1083830A1 - 1-Substituted 4-nitroimidazole compound and process for producing the same - Google Patents

1-Substituted 4-nitroimidazole compound and process for producing the same

Info

Publication number
HK1083830A1
HK1083830A1 HK06103740A HK06103740A HK1083830A1 HK 1083830 A1 HK1083830 A1 HK 1083830A1 HK 06103740 A HK06103740 A HK 06103740A HK 06103740 A HK06103740 A HK 06103740A HK 1083830 A1 HK1083830 A1 HK 1083830A1
Authority
HK
Hong Kong
Prior art keywords
substituted
producing
same
nitroimidazole compound
nitroimidazole
Prior art date
Application number
HK06103740A
Other languages
English (en)
Inventor
Fumitaka Goto
Noriaki Takemura
Tadaaki Otani
Takeshi Hasegawa
Hidetsugu Tsubouchi
Naoto Utsumi
Shigekazu Fujita
Hideaki Kuroda
Takuya Shitsuta
Hirofumi Sasaki
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of HK1083830A1 publication Critical patent/HK1083830A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK06103740A 2002-10-15 2006-03-24 1-Substituted 4-nitroimidazole compound and process for producing the same HK1083830A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002299896 2002-10-15
JP2003037914 2003-02-17
PCT/JP2003/013134 WO2004035547A1 (ja) 2002-10-15 2003-10-14 １位置換―４―ニトロイミダゾール化合物及びその製造法

Publications (1)

Publication Number Publication Date
HK1083830A1 true HK1083830A1 (en) 2006-08-11

Family

ID=32109445

Family Applications (2)

Application Number Title Priority Date Filing Date
HK06103740A HK1083830A1 (en) 2002-10-15 2006-03-24 1-Substituted 4-nitroimidazole compound and process for producing the same
HK14102050.7A HK1188993A1 (en) 2002-10-15 2014-03-03 Method for preparing a 2-halo-4-nitroimidazole compound 2--4-

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK14102050.7A HK1188993A1 (en) 2002-10-15 2014-03-03 Method for preparing a 2-halo-4-nitroimidazole compound 2--4-

Country Status (17)

Country Link
US (4) US7368579B2 (xx)
EP (2) EP2644599B1 (xx)
JP (1) JP5014315B2 (xx)
KR (1) KR100655670B1 (xx)
AR (1) AR041605A1 (xx)
AU (1) AU2003301282B2 (xx)
BR (1) BR0313566A (xx)
CA (1) CA2494710C (xx)
EG (1) EG24885A (xx)
ES (1) ES2526892T3 (xx)
HK (2) HK1083830A1 (xx)
MX (1) MXPA05002414A (xx)
MY (1) MY145079A (xx)
PL (1) PL375103A1 (xx)
RU (1) RU2324682C2 (xx)
TW (2) TW200838855A (xx)
WO (1) WO2004035547A1 (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004035547A1 (ja) * 2002-10-15 2004-04-29 Otsuka Pharmaceutical Co., Ltd. １位置換―４―ニトロイミダゾール化合物及びその製造法
KR100851802B1 (ko) * 2003-10-31 2008-08-13 오쓰까 세이야꾸 가부시키가이샤 결핵의 치료를 위한2,3-디히드로-6-니트로이미다조[2,1-ｂ]옥사졸 화합물
TWI300409B (en) 2004-02-18 2008-09-01 Otsuka Pharma Co Ltd Method for producing 4-nitroimidazole compound
TW200624422A (en) * 2004-09-27 2006-07-16 Otsuka Pharma Co Ltd Process for production of 2-chloro-4-nitroimidazole
CN100338039C (zh) * 2004-11-29 2007-09-19 南京圣和药业有限公司 奥硝唑光学对映体的制备及纯化方法
KR101294921B1 (ko) * 2005-07-28 2013-08-08 오츠카 세이야쿠 가부시키가이샤 2,3-디히드로-6-니트로이미다조〔2,1-ｂ〕옥사졸 유도체 함유 제약 조성물
AR070301A1 (es) 2007-05-08 2010-03-31 Otsuka Pharma Co Ltd Compuesto epoxi y metodo para producir el mismo
US8558005B2 (en) * 2008-08-21 2013-10-15 Dynamit Nobel Gmbh Explosivstoff-Und Systemtechnik Methods for the production of 2-halo-4-nitroimidazole and intermediates thereof
TW201200523A (en) 2010-01-29 2012-01-01 Otsuka Pharma Co Ltd Synthetic intermediate of oxazole compound and method for producing the same
WO2014014845A1 (en) 2012-07-18 2014-01-23 Vertex Pharmaceuticals Incorporated Combination therapy comprising|1 -ethyl-3-[5-[2-{1 -hydroxy-1 -methyl-ethyl}pyrimidin-5-yl]-7-(tetra hydrofuran-2-|yl}-1 h-benzimidazol-2-yl]urea and derivatives thereof to treat mycobacterium|diseases
CN103396369B (zh) * 2013-08-14 2016-03-23 盐城工学院 一种制备2-氯-4-硝基咪唑的方法
JP2020517672A (ja) 2017-04-26 2020-06-18 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 殺有害生物剤としての置換スクシンイミド誘導体
EP3696177A1 (en) 2019-02-12 2020-08-19 Basf Se Heterocyclic compounds for the control of invertebrate pests
WO2020202205A1 (en) * 2019-04-01 2020-10-08 Council Of Scientific And Industrial Research Process for the preparation of derivatives of 1,1-dialkylethane-1,2-diols as useful intermediates
JP2022530775A (ja) 2019-05-01 2022-07-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング （ｒ）－（２－メチルオキシラン－２－イル）メチル ４－ブロモベンゼンスルホネート

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341548A (en) * 1964-04-29 1967-09-12 Hoffmann La Roche Nitroimidazoles and their preparation
US3435049A (en) * 1965-05-19 1969-03-25 Hoffmann La Roche Nitroimidazole derivatives
DE2414280C2 (de) 1974-03-25 1981-12-17 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 1-Methyl-5-nitroimidazolen
US4183941A (en) 1978-08-21 1980-01-15 John R. A. Simoons Treatment of rheumatoid arthritis and related diseases
AR245935A1 (es) 1988-01-15 1994-03-30 Rhone Poulenc Sante Procedimiento para la preparacion de alquil-1 nitro-5 imidazoles.
US5344937A (en) 1993-04-20 1994-09-06 Eli Lilly And Company Alkyl substituted nitroimidazole acetic acids
US5668127A (en) 1995-06-26 1997-09-16 Pathogenesis Corporation Nitroimidazole antibacterial compounds and methods of use thereof
TWI347946B (en) * 2002-10-11 2011-09-01 Otsuka Pharma Co Ltd 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound
WO2004035547A1 (ja) * 2002-10-15 2004-04-29 Otsuka Pharmaceutical Co., Ltd. １位置換―４―ニトロイミダゾール化合物及びその製造法
TWI300409B (en) * 2004-02-18 2008-09-01 Otsuka Pharma Co Ltd Method for producing 4-nitroimidazole compound

Also Published As

Publication number Publication date
TWI331607B (en) 2010-10-11
CA2494710A1 (en) 2004-04-29
HK1188993A1 (en) 2014-05-23
MY145079A (en) 2011-12-15
US7807843B2 (en) 2010-10-05
RU2005114534A (ru) 2006-01-20
EP2644599A1 (en) 2013-10-02
TW200838855A (en) 2008-10-01
TW200410943A (en) 2004-07-01
EG24885A (en) 2010-12-06
EP2644599B1 (en) 2014-12-10
WO2004035547A1 (ja) 2004-04-29
ES2526892T3 (es) 2015-01-16
PL375103A1 (en) 2005-11-28
EP1553088A1 (en) 2005-07-13
US7368579B2 (en) 2008-05-06
BR0313566A (pt) 2005-06-21
CA2494710C (en) 2011-05-03
US20120130082A1 (en) 2012-05-24
JP2009102329A (ja) 2009-05-14
US20060079697A1 (en) 2006-04-13
RU2324682C2 (ru) 2008-05-20
MXPA05002414A (es) 2005-06-22
US20080097107A1 (en) 2008-04-24
AR041605A1 (es) 2005-05-26
KR100655670B1 (ko) 2007-02-28
JP5014315B2 (ja) 2012-08-29
US20080200689A1 (en) 2008-08-21
US8129544B2 (en) 2012-03-06
KR20050046013A (ko) 2005-05-17
AU2003301282B2 (en) 2009-04-30
AU2003301282A1 (en) 2004-05-04
EP1553088A4 (en) 2011-03-02

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20121014