AR245935A1 - Procedimiento para la preparacion de alquil-1 nitro-5 imidazoles. - Google Patents

Procedimiento para la preparacion de alquil-1 nitro-5 imidazoles.

Info

Publication number
AR245935A1
AR245935A1 AR89312974A AR31297489A AR245935A1 AR 245935 A1 AR245935 A1 AR 245935A1 AR 89312974 A AR89312974 A AR 89312974A AR 31297489 A AR31297489 A AR 31297489A AR 245935 A1 AR245935 A1 AR 245935A1
Authority
AR
Argentina
Prior art keywords
alkyl
imidazoles
nitro
preparation
following formula
Prior art date
Application number
AR89312974A
Other languages
English (en)
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8800414A external-priority patent/FR2625997B1/fr
Priority claimed from FR8807773A external-priority patent/FR2632640B1/fr
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Application granted granted Critical
Publication of AR245935A1 publication Critical patent/AR245935A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE ALQUIL-1 NITRO-5 IMIDAZOLES DE LA FORMULA (I), EN LA CUAL R ES HIDROGENO O ALQUILO;R1 ES ALQUILO, DONDE SE HACE ACTUAR UN SULFATO DE ALQUILO DE LA SIGUIENTE FORMULA: R1O-SO2-OR1, SOBRE UN DERIVADO DEL IMIDAZOL QUE RESPONDE A LA SIGUIENTE FORMULA (II), EN LA CUAL X ES UN GRUPO ALCANOILO OXIALQUILO, OPERANDOSE EN UN SOLVENTE ORGANICO, SEGUIDO POR HIDROLISIS EN CALIENTE, EVENTUALMENTE IN SITU, DEL PRODUCTO OBTENIDO.
AR89312974A 1988-01-15 1989-01-12 Procedimiento para la preparacion de alquil-1 nitro-5 imidazoles. AR245935A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8800414A FR2625997B1 (fr) 1988-01-15 1988-01-15 Procede de preparation du dimethyl-1,2 nitro-5 imidazole
FR8807773A FR2632640B1 (fr) 1988-06-10 1988-06-10 Procede de preparation d'alkyl-1 nitro-5 imidazoles

Publications (1)

Publication Number Publication Date
AR245935A1 true AR245935A1 (es) 1994-03-30

Family

ID=26226445

Family Applications (1)

Application Number Title Priority Date Filing Date
AR89312974A AR245935A1 (es) 1988-01-15 1989-01-12 Procedimiento para la preparacion de alquil-1 nitro-5 imidazoles.

Country Status (21)

Country Link
US (1) US4925949A (es)
EP (1) EP0325512B1 (es)
JP (1) JP2539022B2 (es)
KR (1) KR890011856A (es)
CN (1) CN1023221C (es)
AR (1) AR245935A1 (es)
AU (1) AU608932B2 (es)
CA (1) CA1310325C (es)
DE (1) DE68904436T2 (es)
DK (1) DK14589A (es)
ES (1) ES2054035T3 (es)
FI (1) FI890185A (es)
GR (1) GR3006827T3 (es)
HU (1) HU200446B (es)
IE (1) IE890090L (es)
IL (1) IL88943A (es)
MX (1) MX169215B (es)
NO (1) NO171910C (es)
PT (1) PT89442B (es)
SU (1) SU1648249A3 (es)
YU (1) YU46966B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2625999B1 (fr) * 1988-01-15 1990-06-08 Rhone Poulenc Sante Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles
FR2625998B1 (fr) * 1988-01-15 1990-06-08 Rhone Poulenc Sante Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles
FR2659326A1 (fr) * 1990-03-12 1991-09-13 Rhone Poulenc Sante Procede de preparation d'hydroxyalkyl-1 nitro-5 imidazoles.
US5344937A (en) * 1993-04-20 1994-09-06 Eli Lilly And Company Alkyl substituted nitroimidazole acetic acids
CN1046040C (zh) * 1994-11-29 1999-10-27 联华电子股份有限公司 与总线位数相匹配的存贮器直接存取结构
ZA200500918B (en) * 2002-10-15 2006-12-27 Otsuka Pharma Co Ltd 1-substituted 4-nitroimidazole compound and process for producing the same
AR041605A1 (es) * 2002-10-15 2005-05-26 Otsuka Pharma Co Ltd Compuesto 1- sustituido-4-nitroimidazol y metodo para preparar el mismo
TWI300409B (en) * 2004-02-18 2008-09-01 Otsuka Pharma Co Ltd Method for producing 4-nitroimidazole compound
RU2528025C1 (ru) * 2013-03-29 2014-09-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный исследовательский Томский государственный университет" (ТГУ) Способ получения диметридазола
CN108689941B (zh) * 2018-06-08 2023-05-16 湖北省宏源药业科技股份有限公司 一种合成1,2-二甲基-5-硝基咪唑的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1216238A (fr) * 1957-09-14 1960-04-22 Rhone Poulenc Sa Nouveaux dérivés du nitro-5 imidazole et leur préparation
IT1051571B (it) * 1974-03-07 1981-05-20 Finotto Martino Procedimento di fabbricazione di i 2 dimetil 5 nitro imidazolo
DE2414280C2 (de) * 1974-03-25 1981-12-17 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 1-Methyl-5-nitroimidazolen
IT1098864B (it) * 1978-09-19 1985-09-18 Farchemia Spa Processo per la preparazione di nitroimidazoli
DE3026846A1 (de) * 1980-07-16 1982-02-11 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 1,2-dimethyl-5-nitroimidazol
DE3132025A1 (de) * 1981-08-13 1983-03-03 Basf Ag, 6700 Ludwigshafen Verfahren zur gewinnung von 1,2-dimethyl-5-nitroimidazol von hoher reinheit
EP0126183A1 (de) * 1982-12-23 1984-11-28 A. Nattermann & Cie. GmbH Substituierte 5(4)-Nitroimidazole sowie Verfahren zu ihrer Herstellung
FR2625999B1 (fr) * 1988-01-15 1990-06-08 Rhone Poulenc Sante Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles
FR2625998B1 (fr) * 1988-01-15 1990-06-08 Rhone Poulenc Sante Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles

Also Published As

Publication number Publication date
AU2845189A (en) 1989-07-20
FI890185A (fi) 1989-07-16
JPH01213268A (ja) 1989-08-28
CA1310325C (fr) 1992-11-17
ES2054035T3 (es) 1994-08-01
YU46966B (sh) 1994-09-09
AU608932B2 (en) 1991-04-18
HUT49585A (en) 1989-10-30
CN1023221C (zh) 1993-12-22
SU1648249A3 (ru) 1991-05-07
DE68904436T2 (de) 1993-07-29
MX169215B (es) 1993-06-24
JP2539022B2 (ja) 1996-10-02
NO171910C (no) 1993-05-19
NO171910B (no) 1993-02-08
PT89442A (pt) 1990-02-08
PT89442B (pt) 1993-09-30
EP0325512B1 (fr) 1993-01-20
NO890159D0 (no) 1989-01-13
DE68904436D1 (de) 1993-03-04
EP0325512A1 (fr) 1989-07-26
KR890011856A (ko) 1989-08-22
DK14589D0 (da) 1989-01-13
GR3006827T3 (es) 1993-06-30
NO890159L (no) 1989-07-17
HU200446B (en) 1990-06-28
FI890185A0 (fi) 1989-01-13
CN1035824A (zh) 1989-09-27
YU7189A (en) 1990-12-31
IE890090L (en) 1989-07-15
IL88943A0 (en) 1989-08-15
DK14589A (da) 1989-07-16
IL88943A (en) 1994-05-30
US4925949A (en) 1990-05-15

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