HK1183030A1 - 抗病毒的雜環化合物 - Google Patents

抗病毒的雜環化合物

Info

Publication number
HK1183030A1
HK1183030A1 HK13110430.2A HK13110430A HK1183030A1 HK 1183030 A1 HK1183030 A1 HK 1183030A1 HK 13110430 A HK13110430 A HK 13110430A HK 1183030 A1 HK1183030 A1 HK 1183030A1
Authority
HK
Hong Kong
Prior art keywords
antiviral compounds
heterocyclic antiviral
heterocyclic
compounds
antiviral
Prior art date
Application number
HK13110430.2A
Other languages
English (en)
Inventor
Leanna Renee Staben
Francisco Xavier Talamas
Ryan Craig Schoenfeld
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1183030A1 publication Critical patent/HK1183030A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK13110430.2A 2010-07-07 2013-09-09 抗病毒的雜環化合物 HK1183030A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36222010P 2010-07-07 2010-07-07
PCT/EP2011/061180 WO2012004212A1 (en) 2010-07-07 2011-07-04 Heterocyclic antiviral compounds

Publications (1)

Publication Number Publication Date
HK1183030A1 true HK1183030A1 (zh) 2013-12-13

Family

ID=44532771

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13110430.2A HK1183030A1 (zh) 2010-07-07 2013-09-09 抗病毒的雜環化合物

Country Status (14)

Country Link
US (1) US8329712B2 (zh)
EP (1) EP2590960B1 (zh)
JP (1) JP5651239B2 (zh)
KR (1) KR101445506B1 (zh)
CN (1) CN102971305B (zh)
AR (1) AR082187A1 (zh)
BR (1) BR112013000245A2 (zh)
CA (1) CA2801670A1 (zh)
ES (1) ES2481411T3 (zh)
HK (1) HK1183030A1 (zh)
MX (1) MX2012014235A (zh)
RU (1) RU2572558C2 (zh)
TW (1) TWI423975B (zh)
WO (1) WO2012004212A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2477342T3 (es) * 2010-08-13 2014-07-16 F. Hoffmann-La Roche Ag Compuestos heteroc�clicos antivirales
US10968218B2 (en) * 2016-11-03 2021-04-06 Hoffmann-La Roche Inc. Tetrahydropyridopyrimidines for the treatment and prophylaxis of hepatitis B virus infection
KR102645467B1 (ko) 2018-10-18 2024-03-11 삼성디스플레이 주식회사 표시장치의 제조방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2029472C1 (ru) * 1989-09-26 1995-02-27 Сумитомо Кемикал Компани Лимитед Производные урацила, промежуточные соединения, гербицидная композиция и способ борьбы с сорняками
WO2005086853A2 (en) * 2004-03-10 2005-09-22 Primet Precision Materials, Inc. Multi-carbide material manufacture and methods of use
GB0428475D0 (en) * 2004-12-30 2005-02-02 4 Aza Bioscience Nv Pyrido(3,2-D)pyrimidine derivatives and pharmaceutical compositions useful as medicines for the treatment of autoimmune disorders
CA2612788A1 (en) * 2005-06-24 2006-12-28 Steven Cesar Alfons De Jonghe Pyrido(3,2-d)pyrimidines and pharmaceutical compositions useful for treating hepatitis c
US8673929B2 (en) * 2006-07-20 2014-03-18 Gilead Sciences, Inc. 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives and pharmaceutical compositions useful for treating viral infections
US8338435B2 (en) * 2006-07-20 2012-12-25 Gilead Sciences, Inc. Substituted pyrido(3,2-D) pyrimidines and pharmaceutical compositions for treating viral infections
RU2010111551A (ru) * 2007-08-29 2011-10-10 Шеринг Корпорейшн (US) Замещенные индольные производные и способы их применения
NZ618277A (en) 2007-09-17 2015-07-31 Abbvie Bahamas Ltd Uracil or thymine derivative for treating hepatitis c
ATE512954T1 (de) * 2007-09-17 2011-07-15 Abbott Lab Als inhibitoren des hepatitis-c-virus (hcv) geeignete n-phenyldioxohydropyrimidine
BRPI0920513A2 (pt) * 2008-09-26 2019-09-24 F Hoffamann La Roche Ag derivados de pirina ou pirazina para tratar hcv
AR077004A1 (es) * 2009-06-09 2011-07-27 Hoffmann La Roche Compuestos heterociclicos antivirales

Also Published As

Publication number Publication date
WO2012004212A1 (en) 2012-01-12
MX2012014235A (es) 2013-01-28
TW201206932A (en) 2012-02-16
US8329712B2 (en) 2012-12-11
CN102971305B (zh) 2016-02-03
TWI423975B (zh) 2014-01-21
JP2013530198A (ja) 2013-07-25
BR112013000245A2 (pt) 2016-05-24
AR082187A1 (es) 2012-11-21
KR20130036316A (ko) 2013-04-11
JP5651239B2 (ja) 2015-01-07
CN102971305A (zh) 2013-03-13
EP2590960B1 (en) 2014-06-11
RU2572558C2 (ru) 2016-01-20
CA2801670A1 (en) 2012-01-12
KR101445506B1 (ko) 2014-09-26
US20120009144A1 (en) 2012-01-12
ES2481411T3 (es) 2014-07-30
EP2590960A1 (en) 2013-05-15
RU2013102400A (ru) 2014-08-20

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20200704