HK1179871A1 - 作為 氧化酶抑制劑的吡唑並吡啶衍生物 - Google Patents

作為 氧化酶抑制劑的吡唑並吡啶衍生物

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Publication number
HK1179871A1
HK1179871A1 HK13107167.7A HK13107167A HK1179871A1 HK 1179871 A1 HK1179871 A1 HK 1179871A1 HK 13107167 A HK13107167 A HK 13107167A HK 1179871 A1 HK1179871 A1 HK 1179871A1
Authority
HK
Hong Kong
Prior art keywords
nadph
pyridine derivatives
oxidase inhibitors
pyrazolo pyridine
nadph oxidase
Prior art date
Application number
HK13107167.7A
Other languages
English (en)
Inventor
Patrick Page
Mike Orchard
Laetitia Fioraso-Cartier
Bianca Mottironi
Original Assignee
Genkyotex Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genkyotex Sa filed Critical Genkyotex Sa
Publication of HK1179871A1 publication Critical patent/HK1179871A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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HK13107167.7A 2007-03-22 2013-06-19 作為 氧化酶抑制劑的吡唑並吡啶衍生物 HK1179871A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89628407P 2007-03-22 2007-03-22
EP07109555A EP2002835A1 (en) 2007-06-04 2007-06-04 Pyrazolo pyridine derivatives as NADPH oxidase inhibitors

Publications (1)

Publication Number Publication Date
HK1179871A1 true HK1179871A1 (zh) 2013-10-11

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
HK10108322.0A HK1141734A1 (zh) 2007-03-22 2010-09-02 作為 氧化酶抑制劑的吡唑並吡啶衍生物
HK13107167.7A HK1179871A1 (zh) 2007-03-22 2013-06-19 作為 氧化酶抑制劑的吡唑並吡啶衍生物

Family Applications Before (1)

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HK10108322.0A HK1141734A1 (zh) 2007-03-22 2010-09-02 作為 氧化酶抑制劑的吡唑並吡啶衍生物

Country Status (18)

Country Link
US (2) US8389518B2 (zh)
EP (3) EP2002835A1 (zh)
JP (2) JP5715340B2 (zh)
CN (2) CN101686967B (zh)
AU (1) AU2008228186C1 (zh)
BR (1) BRPI0808824B8 (zh)
CA (1) CA2676954C (zh)
CY (2) CY1113556T1 (zh)
DK (2) DK2139477T3 (zh)
ES (2) ES2398994T3 (zh)
HK (2) HK1141734A1 (zh)
HR (2) HRP20130143T1 (zh)
IL (1) IL201009A (zh)
PL (2) PL2139477T3 (zh)
PT (2) PT2545918E (zh)
RS (2) RS52640B (zh)
SI (2) SI2139477T1 (zh)
WO (1) WO2008113856A1 (zh)

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KR102507967B1 (ko) 2016-09-09 2023-03-09 인사이트 코포레이션 Hpk1 조절제로서의 피라졸로피리딘 유도체 및 암을 치료하기 위한 이의 용도
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WO2018152220A1 (en) 2017-02-15 2018-08-23 Incyte Corporation Pyrazolopyridine compounds and uses thereof
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US10722495B2 (en) 2017-09-08 2020-07-28 Incyte Corporation Cyanoindazole compounds and uses thereof
EP3479843A1 (en) 2017-11-01 2019-05-08 GenKyoTex Suisse SA Use of nox inhibitors for treatment of cancer
MX2020008656A (es) 2018-02-20 2020-12-09 Incyte Corp Derivados de n-(fenil)-2-(fenil)pirimidina-4-carboxamida y compuestos relacionados como inhibidores de la cinasa de progenitores hematopoyeticos 1 (hpk1) para tratar el cancer.
US10752635B2 (en) 2018-02-20 2020-08-25 Incyte Corporation Indazole compounds and uses thereof
US10745388B2 (en) 2018-02-20 2020-08-18 Incyte Corporation Indazole compounds and uses thereof
US11299473B2 (en) 2018-04-13 2022-04-12 Incyte Corporation Benzimidazole and indole compounds and uses thereof
CN109846900B (zh) * 2018-05-25 2021-07-23 四川大学 还原型烟酰胺腺嘌呤二核苷酸磷酸在制备抗病毒药物中的用途
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BRPI0808824B1 (pt) 2020-10-13
EP2545918B1 (en) 2014-08-06
BRPI0808824B8 (pt) 2021-05-25
EP2139477B1 (en) 2012-12-12
CA2676954A1 (en) 2008-09-25
WO2008113856A1 (en) 2008-09-25
SI2139477T1 (sl) 2013-02-28
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