HK1178159A1 - -吡咯烷- -基-乙氧基 -三氧雜- -三氮雜-四環 二十六碳- -壬烯檸檬酸鹽 - Google Patents

-吡咯烷- -基-乙氧基 -三氧雜- -三氮雜-四環 二十六碳- -壬烯檸檬酸鹽

Info

Publication number
HK1178159A1
HK1178159A1 HK13105191.1A HK13105191A HK1178159A1 HK 1178159 A1 HK1178159 A1 HK 1178159A1 HK 13105191 A HK13105191 A HK 13105191A HK 1178159 A1 HK1178159 A1 HK 1178159A1
Authority
HK
Hong Kong
Prior art keywords
nonaene
hexacosa
trioxa
tetracyclo
triaza
Prior art date
Application number
HK13105191.1A
Other languages
English (en)
Inventor
.迪莫克
李靜霞
.威廉
Original Assignee
生物醫藥有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 生物醫藥有限公司 filed Critical 生物醫藥有限公司
Publication of HK1178159A1 publication Critical patent/HK1178159A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK13105191.1A 2009-07-15 2013-04-29 -吡咯烷- -基-乙氧基 -三氧雜- -三氮雜-四環 二十六碳- -壬烯檸檬酸鹽 HK1178159A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22560909P 2009-07-15 2009-07-15
PCT/SG2010/000265 WO2011008172A1 (en) 2009-07-15 2010-07-14 9e-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza- tetracyclo[18.3.1.1(2,5).1(14)18)]hexacosa-1(24),2,4,9,14,16,18(26),20,22-nonaene citrate salt

Publications (1)

Publication Number Publication Date
HK1178159A1 true HK1178159A1 (zh) 2013-09-06

Family

ID=42790728

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13105191.1A HK1178159A1 (zh) 2009-07-15 2013-04-29 -吡咯烷- -基-乙氧基 -三氧雜- -三氮雜-四環 二十六碳- -壬烯檸檬酸鹽

Country Status (19)

Country Link
US (1) US9062074B2 (zh)
EP (1) EP2454266B1 (zh)
JP (2) JP6013911B2 (zh)
CN (1) CN102762577B (zh)
AR (2) AR077483A1 (zh)
BR (1) BR112012000750B1 (zh)
CA (1) CA2768210C (zh)
DK (1) DK2454266T3 (zh)
ES (1) ES2429525T3 (zh)
HK (1) HK1178159A1 (zh)
HR (1) HRP20130941T1 (zh)
MX (1) MX2012000680A (zh)
PL (1) PL2454266T3 (zh)
PT (1) PT2454266E (zh)
RU (1) RU2543721C2 (zh)
SI (1) SI2454266T1 (zh)
SM (1) SMT201300112B (zh)
TW (1) TWI537276B (zh)
WO (1) WO2011008172A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10786461B2 (en) 2014-11-17 2020-09-29 Context Biopharma Inc. Onapristone extended-release compositions and methods
BR112018005999A2 (pt) 2015-09-25 2019-01-08 Context Biopharma Inc métodos para a produção de intermediários de onapristona
KR20180113988A (ko) 2015-12-15 2018-10-17 컨텍스트 바이오파마 인코포레이티드 비정질 오나프리스톤 조성물 및 그 제조방법
US20180148471A1 (en) 2016-11-30 2018-05-31 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110603A (en) * 1993-05-27 1998-08-29 Novartis Ag Tetrahydropyran derivatives
WO2004078682A2 (en) 2003-03-05 2004-09-16 Irm Llc Cyclic compounds and compositions as protein kinase inhibitors
KR101499594B1 (ko) * 2005-11-16 2015-03-09 씨티아이 바이오파마 코포레이션 산소가 결합된 피리미딘 유도체

Also Published As

Publication number Publication date
TW201107336A (en) 2011-03-01
RU2543721C2 (ru) 2015-03-10
BR112012000750B1 (pt) 2021-05-25
JP2015164941A (ja) 2015-09-17
SI2454266T1 (sl) 2013-10-30
CA2768210C (en) 2017-08-15
MX2012000680A (es) 2012-02-28
AR077483A1 (es) 2011-08-31
TWI537276B (zh) 2016-06-11
AR114987A2 (es) 2020-11-11
DK2454266T3 (da) 2013-09-08
SMT201300112B (it) 2013-11-08
US9062074B2 (en) 2015-06-23
CN102762577B (zh) 2015-01-07
RU2012105044A (ru) 2013-08-20
US20120196876A1 (en) 2012-08-02
JP6013911B2 (ja) 2016-10-25
BR112012000750A2 (pt) 2016-08-09
EP2454266A1 (en) 2012-05-23
CN102762577A (zh) 2012-10-31
PT2454266E (pt) 2013-10-10
ES2429525T3 (es) 2013-11-15
CA2768210A1 (en) 2011-01-20
HRP20130941T1 (hr) 2013-11-08
WO2011008172A1 (en) 2011-01-20
PL2454266T3 (pl) 2014-01-31
JP2012533539A (ja) 2012-12-27
BR112012000750A8 (pt) 2018-02-06
EP2454266B1 (en) 2013-07-10

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