HK1168102A1 - Process for the preparation of a compound useful as an inhibitor of tafia - Google Patents
Process for the preparation of a compound useful as an inhibitor of tafiaInfo
- Publication number
- HK1168102A1 HK1168102A1 HK12108882.0A HK12108882A HK1168102A1 HK 1168102 A1 HK1168102 A1 HK 1168102A1 HK 12108882 A HK12108882 A HK 12108882A HK 1168102 A1 HK1168102 A1 HK 1168102A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- preparation
- tafia
- inhibitor
- compound useful
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09290366 | 2009-05-15 | ||
| PCT/EP2010/056426 WO2010130718A1 (en) | 2009-05-15 | 2010-05-11 | Process for the preparation of a compound useful as an inhibitor of tafia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1168102A1 true HK1168102A1 (en) | 2012-12-21 |
Family
ID=41259362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12108882.0A HK1168102A1 (en) | 2009-05-15 | 2012-09-12 | Process for the preparation of a compound useful as an inhibitor of tafia |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8865906B2 (pt) |
| EP (1) | EP2430002B1 (pt) |
| JP (1) | JP5706397B2 (pt) |
| KR (1) | KR20120016651A (pt) |
| CN (1) | CN102459192B (pt) |
| AU (1) | AU2010247431B2 (pt) |
| BR (1) | BRPI1010571A2 (pt) |
| CA (1) | CA2760748A1 (pt) |
| CY (1) | CY1114493T1 (pt) |
| DK (1) | DK2430002T3 (pt) |
| ES (1) | ES2431068T3 (pt) |
| HK (1) | HK1168102A1 (pt) |
| HR (1) | HRP20130881T1 (pt) |
| IL (1) | IL216202A (pt) |
| MX (1) | MX2011011849A (pt) |
| MY (1) | MY157304A (pt) |
| PL (1) | PL2430002T3 (pt) |
| PT (1) | PT2430002E (pt) |
| RS (1) | RS52963B (pt) |
| RU (1) | RU2538506C2 (pt) |
| SG (1) | SG176558A1 (pt) |
| SI (1) | SI2430002T1 (pt) |
| WO (1) | WO2010130718A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2548871T3 (da) * | 2010-03-18 | 2017-11-06 | Daiichi Sankyo Co Ltd | Cycloalkylsubstitueret imidazolderivat |
| JP5778133B2 (ja) * | 2010-03-18 | 2015-09-16 | 第一三共株式会社 | シクロプロパンカルボン酸誘導体 |
| SG189420A1 (en) | 2010-11-11 | 2013-05-31 | Sanofi Sa | Process for the preparation of 3-(6-amino-pyridin-3yl)-2-acrylic acid derivatives |
| EP2782575B1 (en) | 2011-11-25 | 2016-04-20 | Sanofi | Crystalline salts of r)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1h-imidazol-4-yl)-propionic acid |
| US9102657B2 (en) | 2011-11-25 | 2015-08-11 | Sanofi | Sodium salt of (R)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1H-imidazol-4-yl)-propionic acid |
| EP3184095A1 (en) | 2013-05-23 | 2017-06-28 | IP Gesellschaft für Management mbH | Administration units comprising polymorph 1 of 2-(2-methylamino-pyrimidin-4-yl]-1h-indole-5-carboxylic acid [(s)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl]-amide |
| NZ755847A (en) * | 2017-03-01 | 2021-12-24 | Boehringer Ingelheim Int | Transition metal-catalyzed protodecarboxylation of α-halo-acrylic acid derivatives |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4216218A (en) * | 1979-02-23 | 1980-08-05 | American Hoechst Corporation | Antidepressant and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines |
| IT1177017B (it) * | 1984-10-22 | 1987-08-26 | Ravizza Spa | Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico |
| FR2693192B1 (fr) * | 1992-07-02 | 1994-08-12 | Rhone Poulenc Agrochimie | Dérivés de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides. |
| BR9917112A (pt) * | 1998-12-24 | 2002-01-29 | Fujisawa Pharmaceutical Co | Compostos de imidazol e seu uso medicinal |
| US8710232B2 (en) | 2004-04-22 | 2014-04-29 | Sanofi-Aventis Deutschland Gmbh | Imidazole derivatives used as TAFIa inhibitors |
| DE102004020186A1 (de) * | 2004-04-22 | 2005-11-17 | Aventis Pharma Deutschland Gmbh | Heterocyclylessigsäuren als Inhibitoren von TAFla |
-
2010
- 2010-05-11 RU RU2011151044/04A patent/RU2538506C2/ru not_active IP Right Cessation
- 2010-05-11 DK DK10721758.0T patent/DK2430002T3/da active
- 2010-05-11 KR KR1020117029984A patent/KR20120016651A/ko not_active Application Discontinuation
- 2010-05-11 BR BRPI1010571A patent/BRPI1010571A2/pt not_active IP Right Cessation
- 2010-05-11 WO PCT/EP2010/056426 patent/WO2010130718A1/en active Application Filing
- 2010-05-11 JP JP2012510266A patent/JP5706397B2/ja not_active Expired - Fee Related
- 2010-05-11 EP EP10721758.0A patent/EP2430002B1/en active Active
- 2010-05-11 US US13/319,474 patent/US8865906B2/en not_active Expired - Fee Related
- 2010-05-11 PL PL10721758T patent/PL2430002T3/pl unknown
- 2010-05-11 SG SG2011084332A patent/SG176558A1/en unknown
- 2010-05-11 ES ES10721758T patent/ES2431068T3/es active Active
- 2010-05-11 SI SI201030336T patent/SI2430002T1/sl unknown
- 2010-05-11 PT PT107217580T patent/PT2430002E/pt unknown
- 2010-05-11 RS RS20130435A patent/RS52963B/en unknown
- 2010-05-11 MX MX2011011849A patent/MX2011011849A/es active IP Right Grant
- 2010-05-11 CA CA2760748A patent/CA2760748A1/en not_active Abandoned
- 2010-05-11 MY MYPI2011004871A patent/MY157304A/en unknown
- 2010-05-11 AU AU2010247431A patent/AU2010247431B2/en not_active Ceased
- 2010-05-11 CN CN201080030161.5A patent/CN102459192B/zh not_active Expired - Fee Related
-
2011
- 2011-11-08 IL IL216202A patent/IL216202A/en not_active IP Right Cessation
-
2012
- 2012-09-12 HK HK12108882.0A patent/HK1168102A1/xx not_active IP Right Cessation
-
2013
- 2013-09-18 HR HRP20130881AT patent/HRP20130881T1/hr unknown
- 2013-10-09 CY CY20131100888T patent/CY1114493T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012526763A (ja) | 2012-11-01 |
| CA2760748A1 (en) | 2010-11-18 |
| CN102459192A (zh) | 2012-05-16 |
| PT2430002E (pt) | 2013-09-11 |
| MY157304A (en) | 2016-05-31 |
| CY1114493T1 (el) | 2016-10-05 |
| IL216202A (en) | 2015-07-30 |
| BRPI1010571A2 (pt) | 2019-09-24 |
| US8865906B2 (en) | 2014-10-21 |
| RU2538506C2 (ru) | 2015-01-10 |
| AU2010247431A1 (en) | 2011-12-01 |
| CN102459192B (zh) | 2015-06-24 |
| WO2010130718A1 (en) | 2010-11-18 |
| EP2430002B1 (en) | 2013-07-24 |
| DK2430002T3 (da) | 2013-11-04 |
| AU2010247431B2 (en) | 2015-02-19 |
| ES2431068T3 (es) | 2013-11-25 |
| US20120245358A1 (en) | 2012-09-27 |
| KR20120016651A (ko) | 2012-02-24 |
| PL2430002T3 (pl) | 2013-12-31 |
| RU2011151044A (ru) | 2013-06-20 |
| MX2011011849A (es) | 2011-12-08 |
| EP2430002A1 (en) | 2012-03-21 |
| IL216202A0 (en) | 2012-01-31 |
| SI2430002T1 (sl) | 2013-10-30 |
| HRP20130881T1 (hr) | 2013-10-25 |
| SG176558A1 (en) | 2012-01-30 |
| RS52963B (en) | 2014-02-28 |
| JP5706397B2 (ja) | 2015-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20170511 |