DK2430002T3 - FREMGANGSMÅDE TIL FREMSTILLING AF EN FORBINDELSE, DER ER ANVENDELIG SOM EN INHIBITOR AF TAFla - Google Patents
FREMGANGSMÅDE TIL FREMSTILLING AF EN FORBINDELSE, DER ER ANVENDELIG SOM EN INHIBITOR AF TAFlaInfo
- Publication number
- DK2430002T3 DK2430002T3 DK10721758.0T DK10721758T DK2430002T3 DK 2430002 T3 DK2430002 T3 DK 2430002T3 DK 10721758 T DK10721758 T DK 10721758T DK 2430002 T3 DK2430002 T3 DK 2430002T3
- Authority
- DK
- Denmark
- Prior art keywords
- tafla
- inhibitor
- preparing
- procedure
- relationship used
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09290366 | 2009-05-15 | ||
PCT/EP2010/056426 WO2010130718A1 (en) | 2009-05-15 | 2010-05-11 | Process for the preparation of a compound useful as an inhibitor of tafia |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2430002T3 true DK2430002T3 (da) | 2013-11-04 |
Family
ID=41259362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10721758.0T DK2430002T3 (da) | 2009-05-15 | 2010-05-11 | FREMGANGSMÅDE TIL FREMSTILLING AF EN FORBINDELSE, DER ER ANVENDELIG SOM EN INHIBITOR AF TAFla |
Country Status (23)
Country | Link |
---|---|
US (1) | US8865906B2 (da) |
EP (1) | EP2430002B1 (da) |
JP (1) | JP5706397B2 (da) |
KR (1) | KR20120016651A (da) |
CN (1) | CN102459192B (da) |
AU (1) | AU2010247431B2 (da) |
BR (1) | BRPI1010571A2 (da) |
CA (1) | CA2760748A1 (da) |
CY (1) | CY1114493T1 (da) |
DK (1) | DK2430002T3 (da) |
ES (1) | ES2431068T3 (da) |
HK (1) | HK1168102A1 (da) |
HR (1) | HRP20130881T1 (da) |
IL (1) | IL216202A (da) |
MX (1) | MX2011011849A (da) |
MY (1) | MY157304A (da) |
PL (1) | PL2430002T3 (da) |
PT (1) | PT2430002E (da) |
RS (1) | RS52963B (da) |
RU (1) | RU2538506C2 (da) |
SG (1) | SG176558A1 (da) |
SI (1) | SI2430002T1 (da) |
WO (1) | WO2010130718A1 (da) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX358628B (es) * | 2010-03-18 | 2018-08-28 | Daiichi Sankyo Co Ltd | Derivado de imidazol sustituido con cicloalquilo. |
JP5778133B2 (ja) * | 2010-03-18 | 2015-09-16 | 第一三共株式会社 | シクロプロパンカルボン酸誘導体 |
CN103201269A (zh) * | 2010-11-11 | 2013-07-10 | 赛诺菲 | 3-(6-氨基-吡啶-3基)-2-丙烯酸衍生物的制备方法 |
WO2013076178A1 (en) | 2011-11-25 | 2013-05-30 | Sanofi | Crystalline salts of r)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1h-imidazol-4-yl)-propionic acid |
EP2782576B1 (en) | 2011-11-25 | 2016-05-18 | Sanofi | Sodium salt of (r)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1h-imidazol-4-yl)-propionic acid |
EP2805705B1 (en) | 2013-05-23 | 2016-11-09 | IP Gesellschaft für Management mbH | Packaging with one or more administration units comprising a sodium salt of (R)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1 H-imidazol-4-yl)-propionic acid |
DK3589606T3 (da) * | 2017-03-01 | 2024-01-02 | Boehringer Ingelheim Int | Overgangsmetal-katalyseret protodecarboxylering af alfa-halo-akrylsyrederivater |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4216218A (en) * | 1979-02-23 | 1980-08-05 | American Hoechst Corporation | Antidepressant and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines |
IT1177017B (it) * | 1984-10-22 | 1987-08-26 | Ravizza Spa | Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico |
FR2693192B1 (fr) * | 1992-07-02 | 1994-08-12 | Rhone Poulenc Agrochimie | Dérivés de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides. |
KR20010094731A (ko) * | 1998-12-24 | 2001-11-01 | 후지야마 아키라 | 이미다졸 화합물 및 그의 의약 용도 |
US8710232B2 (en) | 2004-04-22 | 2014-04-29 | Sanofi-Aventis Deutschland Gmbh | Imidazole derivatives used as TAFIa inhibitors |
DE102004020186A1 (de) * | 2004-04-22 | 2005-11-17 | Aventis Pharma Deutschland Gmbh | Heterocyclylessigsäuren als Inhibitoren von TAFla |
-
2010
- 2010-05-11 CN CN201080030161.5A patent/CN102459192B/zh not_active Expired - Fee Related
- 2010-05-11 WO PCT/EP2010/056426 patent/WO2010130718A1/en active Application Filing
- 2010-05-11 AU AU2010247431A patent/AU2010247431B2/en not_active Ceased
- 2010-05-11 SI SI201030336T patent/SI2430002T1/sl unknown
- 2010-05-11 SG SG2011084332A patent/SG176558A1/en unknown
- 2010-05-11 KR KR1020117029984A patent/KR20120016651A/ko not_active Application Discontinuation
- 2010-05-11 US US13/319,474 patent/US8865906B2/en not_active Expired - Fee Related
- 2010-05-11 BR BRPI1010571A patent/BRPI1010571A2/pt not_active IP Right Cessation
- 2010-05-11 DK DK10721758.0T patent/DK2430002T3/da active
- 2010-05-11 RS RS20130435A patent/RS52963B/en unknown
- 2010-05-11 ES ES10721758T patent/ES2431068T3/es active Active
- 2010-05-11 JP JP2012510266A patent/JP5706397B2/ja not_active Expired - Fee Related
- 2010-05-11 MY MYPI2011004871A patent/MY157304A/en unknown
- 2010-05-11 MX MX2011011849A patent/MX2011011849A/es active IP Right Grant
- 2010-05-11 PL PL10721758T patent/PL2430002T3/pl unknown
- 2010-05-11 EP EP10721758.0A patent/EP2430002B1/en active Active
- 2010-05-11 CA CA2760748A patent/CA2760748A1/en not_active Abandoned
- 2010-05-11 PT PT107217580T patent/PT2430002E/pt unknown
- 2010-05-11 RU RU2011151044/04A patent/RU2538506C2/ru not_active IP Right Cessation
-
2011
- 2011-11-08 IL IL216202A patent/IL216202A/en not_active IP Right Cessation
-
2012
- 2012-09-12 HK HK12108882.0A patent/HK1168102A1/xx not_active IP Right Cessation
-
2013
- 2013-09-18 HR HRP20130881AT patent/HRP20130881T1/hr unknown
- 2013-10-09 CY CY20131100888T patent/CY1114493T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
US8865906B2 (en) | 2014-10-21 |
PL2430002T3 (pl) | 2013-12-31 |
KR20120016651A (ko) | 2012-02-24 |
HK1168102A1 (en) | 2012-12-21 |
AU2010247431A1 (en) | 2011-12-01 |
JP5706397B2 (ja) | 2015-04-22 |
SG176558A1 (en) | 2012-01-30 |
CA2760748A1 (en) | 2010-11-18 |
PT2430002E (pt) | 2013-09-11 |
IL216202A (en) | 2015-07-30 |
IL216202A0 (en) | 2012-01-31 |
RU2011151044A (ru) | 2013-06-20 |
RS52963B (en) | 2014-02-28 |
MY157304A (en) | 2016-05-31 |
SI2430002T1 (sl) | 2013-10-30 |
EP2430002A1 (en) | 2012-03-21 |
RU2538506C2 (ru) | 2015-01-10 |
WO2010130718A1 (en) | 2010-11-18 |
CY1114493T1 (el) | 2016-10-05 |
HRP20130881T1 (hr) | 2013-10-25 |
CN102459192A (zh) | 2012-05-16 |
MX2011011849A (es) | 2011-12-08 |
US20120245358A1 (en) | 2012-09-27 |
JP2012526763A (ja) | 2012-11-01 |
EP2430002B1 (en) | 2013-07-24 |
BRPI1010571A2 (pt) | 2019-09-24 |
CN102459192B (zh) | 2015-06-24 |
ES2431068T3 (es) | 2013-11-25 |
AU2010247431B2 (en) | 2015-02-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK2791134T3 (da) | Kemisk forbindelse, der er anvendelig som mellemprodukt til fremstilling af en catechol-o-methyltransferasehæmmer | |
DK2310382T3 (da) | Amidophenoxyindazoler, der er anvendelige som hæmmere af c-met | |
DK2421825T3 (da) | Azetidinyldiamider som monoacylglycerollipase-inhibitorer | |
DK2662352T3 (da) | Fremgangsmåde til fremstilling af phenylacetamidforbindelse | |
DK2470546T3 (da) | HEXAHYDROOXAZINOPTERIDIN- forbindelser til anvendelse som mTOR INHIBITORER | |
DK2346888T3 (da) | Fremgangsmåde til fremstilling af som SGLT-inhibitorer anvendelige forbindelser | |
DK2746265T3 (da) | Heterocyclisk derivat som mikrosomal prostaglandin-E-syntase-(mPGEs)-inhibitor | |
DK2693881T3 (da) | Substituerede n-phenylpyrimidin-2-amin-analoger som inhibitorer af axl-kinase | |
DK2467204T3 (da) | Fremgangsmåde til fremstilling af en sorbent | |
DK2496562T3 (da) | Fremgangsmåde til fremstilling af calcobutrol | |
DK3406337T3 (da) | Fremgangsmåde til fremstilling af en hydrokrakningskatalysator | |
DK3511330T3 (da) | Syntetisk mellemprodukt, der er anvendeligt til fremstilling af triazolopyridin-c-met-inhibitorer | |
DK2406253T3 (da) | Benzofuranylderivater anvendt som glucokinase-inhibitorer | |
DK2491037T3 (da) | Quinazolin-4(3h)-onderivater, der anvendes som pi3-kinase-inhibitorer | |
DK2691079T3 (da) | Bionedbrydelige sammensætninger, der er egnet til kontrolleret udløsning | |
DK2242750T3 (da) | Konformationelt begrænsede biphenyl-derivater til anvendelse som hepatitis C-virusinhibitorer | |
DK2475657T3 (da) | 5-Alkynylthien-2-ylcarboxylsyrer som inhibitorer af flaviviridae-vira | |
DK2429486T3 (da) | Fremgangsmåde til fremstilling af en tværbundet gel | |
DK2204453T3 (da) | Fremgangsmåde til celle-fri fremstilling af kemikalier | |
DK2411397T3 (da) | Isothiazol-pyrimidindionderivater som modulatorer af TRPA1 | |
DK2526425T3 (da) | Fremgangsmåde til diagnosticering af endometriel receptivitet | |
DK2595948T3 (da) | Fremgangsmåde til fremstilling af ingenol-3-angelat | |
DK2421819T3 (da) | Fremgangsmåde til iodering af aromatiske forbindelser | |
DK2424959T3 (da) | Fremgangsmåde til fremstilling af en hydrokrakningskatalysator | |
DK2430002T3 (da) | FREMGANGSMÅDE TIL FREMSTILLING AF EN FORBINDELSE, DER ER ANVENDELIG SOM EN INHIBITOR AF TAFla |