MX2011010934A - Proceso para la preparacion de un ester del acido bifenil-2-il-carbamico. - Google Patents

Proceso para la preparacion de un ester del acido bifenil-2-il-carbamico.

Info

Publication number
MX2011010934A
MX2011010934A MX2011010934A MX2011010934A MX2011010934A MX 2011010934 A MX2011010934 A MX 2011010934A MX 2011010934 A MX2011010934 A MX 2011010934A MX 2011010934 A MX2011010934 A MX 2011010934A MX 2011010934 A MX2011010934 A MX 2011010934A
Authority
MX
Mexico
Prior art keywords
preparation
biphenyl
acid ester
ylcarbamic acid
compound
Prior art date
Application number
MX2011010934A
Other languages
English (en)
Inventor
Matthew Peter John
Dean David Edney
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MX2011010934A publication Critical patent/MX2011010934A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/33—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Abstract

Un proceso para la preparación del compuesto de la fórmula (II): (ver fórmula (II)) Un proceso para la preparación del compuesto de la fórmula (ver fórmula (VI) con un compuesto de la fórmula (IV): (ver fórmula (IV)) en un solvente adecuado.
MX2011010934A 2009-04-14 2010-04-14 Proceso para la preparacion de un ester del acido bifenil-2-il-carbamico. MX2011010934A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16904609P 2009-04-14 2009-04-14
PCT/EP2010/054893 WO2010119064A1 (en) 2009-04-14 2010-04-14 Process for the preparation of a biphenyl-2-ylcarbamic acid ester

Publications (1)

Publication Number Publication Date
MX2011010934A true MX2011010934A (es) 2011-11-02

Family

ID=42224367

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011010934A MX2011010934A (es) 2009-04-14 2010-04-14 Proceso para la preparacion de un ester del acido bifenil-2-il-carbamico.

Country Status (15)

Country Link
US (1) US8519138B2 (es)
EP (1) EP2419409B1 (es)
JP (2) JP5540075B2 (es)
KR (1) KR101720154B1 (es)
CN (1) CN102395563B (es)
AU (1) AU2010238504B2 (es)
BR (1) BRPI1013562B1 (es)
CA (1) CA2758353C (es)
EA (1) EA022030B1 (es)
ES (1) ES2535326T3 (es)
IL (1) IL215550A (es)
MX (1) MX2011010934A (es)
SG (1) SG175023A1 (es)
WO (1) WO2010119064A1 (es)
ZA (1) ZA201107378B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT107101A (pt) 2013-08-02 2015-02-02 Univ De Coimbra Painéis flexíveis de aerogel hidrofóbico reforçado com feltro de fibras
CN106632257B (zh) * 2016-12-15 2019-02-12 上海市奉贤区中心医院 Gsk961081及其中间体的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU506657B2 (en) * 1975-12-10 1980-01-17 Wellcome Foundation Limited, The Isoquinoline derivatives
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
ES2351392T3 (es) * 2003-02-14 2011-02-03 Theravance Inc Derivados bifenilo que tienen actividad agonista de receptores beta2-adrenérgicos y actividad antagonista de receptores muscarínicos.
EP1615881A2 (en) * 2003-04-01 2006-01-18 Theravance, Inc. Diarylmethyl and related compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
CA2543858C (en) * 2003-11-21 2014-04-15 Theravance, Inc. Compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
TWI374883B (en) * 2004-08-16 2012-10-21 Theravance Inc Crystalline form of a biphenyl compound
EP1833822A2 (en) * 2004-08-16 2007-09-19 Theravance, Inc. Compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
JP2008546695A (ja) * 2005-06-13 2008-12-25 セラヴァンス， インコーポレーテッド ムスカリン受容体アンタゴニストとして有用なビフェニル化合物
GB0602778D0 (en) 2006-02-10 2006-03-22 Glaxo Group Ltd Novel compound
TW200811104A (en) * 2006-04-25 2008-03-01 Theravance Inc Crystalline forms of a dimethylphenyl compound

Also Published As

Publication number Publication date
CN102395563B (zh) 2015-05-20
EP2419409A1 (en) 2012-02-22
SG175023A1 (en) 2011-11-28
JP2014193873A (ja) 2014-10-09
CA2758353A1 (en) 2010-10-21
AU2010238504B2 (en) 2015-04-16
US20120046469A1 (en) 2012-02-23
EA022030B1 (ru) 2015-10-30
KR101720154B1 (ko) 2017-03-27
ZA201107378B (en) 2013-03-27
IL215550A (en) 2016-03-31
EA201190203A1 (ru) 2012-05-30
AU2010238504A1 (en) 2011-11-03
WO2010119064A1 (en) 2010-10-21
BRPI1013562A2 (pt) 2020-08-18
EP2419409B1 (en) 2015-01-28
US8519138B2 (en) 2013-08-27
KR20120006054A (ko) 2012-01-17
CA2758353C (en) 2017-06-06
JP5540075B2 (ja) 2014-07-02
JP5714748B2 (ja) 2015-05-07
CN102395563A (zh) 2012-03-28
ES2535326T3 (es) 2015-05-08
BRPI1013562B1 (pt) 2021-08-03
JP2012523447A (ja) 2012-10-04
IL215550A0 (en) 2011-12-29

Similar Documents

Publication Publication Date Title
MX2009001840A (es) Procedimiento para la preparacion de derivados de acido 3-dihalometilpirazol-4-carboxilico.
NZ603268A (en) Process for synthesizing oxidized lactam compounds
TW200942513A (en) Process for the preparation of fatty acid alkyl esters
MY150280A (en) Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid
IL223328A0 (en) Process for preparing a biphenyl-2-ylcarbamic acid
MX2012001411A (es) Proceso para la preparacion de derivados de acido 1-(2-halobifenil-4-il)-ciclopropanocarboxilico.
HK1168102A1 (en) Process for the preparation of a compound useful as an inhibitor of tafia
MX2012002818A (es) Nuevo procedimiento de sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable.
PL2588439T3 (pl) Sposób wytwarzania kwasu mrówkowego drogą reakcji ditlenku węgla z wodorem
MX2010009926A (es) Nuevo proceso para la preparacion de derivados de acido ciclohexancarboxilico.
MX2012001722A (es) Nuevo procedimiento de sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable.
UA117849C2 (uk) Спосіб одержання 3-заміщених складних ефірів (індол-1-іл)-оцтової кислоти
MX2010003184A (es) Nuevo procedimiento de sinstesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable.
MX2013004193A (es) Procedimiento para la preparacion de derivados de acido 3-(6-amino-piridin-3-il)-2-acrilico.
MX2011010934A (es) Proceso para la preparacion de un ester del acido bifenil-2-il-carbamico.
IL241806A0 (en) Processes for the preparation of an ester of 5-formyl-pyridine-3,2-carboxylic acid
NZ598278A (en) Process for preparing biphenyl imidazole compounds
MX369283B (es) Preparacion de 2-amino-5-ciano-n, 3-dimetilbenzamida.
MX2013002656A (es) Nuevo proceso.
MX2011009734A (es) Nuevo procedimiento de preparacion de compuestos de enaminocarbonilio.
MX2011009731A (es) Nuevo procedimiento de preparacion de compuestos de enaminocarbonilo.
MX2013002990A (es) Nuevo procedimiento de sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable.
MX2009001508A (es) Un proceso novedoso para preparar ester de acido 3-amino-5-fluoro-4-dialcoxipentanoico.
TN2010000531A1 (en) Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid
UA44354U (ru) Соединение 2-(n-ортохлорфенилсукцинимидо-3)-меркаптобензойная кислота с потенциальными биологическими свойствами

Legal Events

Date Code Title Description
FG Grant or registration