HK1163087A1 - 得自於藤黃樹脂的經分餾的產物及其醫藥用途 - Google Patents
得自於藤黃樹脂的經分餾的產物及其醫藥用途Info
- Publication number
- HK1163087A1 HK1163087A1 HK12103749.4A HK12103749A HK1163087A1 HK 1163087 A1 HK1163087 A1 HK 1163087A1 HK 12103749 A HK12103749 A HK 12103749A HK 1163087 A1 HK1163087 A1 HK 1163087A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- same
- products obtained
- medical uses
- fractionated products
- gamboge resin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW099119107A TWI432191B (zh) | 2010-06-11 | 2010-06-11 | 分離自藤黃樹脂的化合物以及包含有此等化合物的藥學組成物 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1163087A1 true HK1163087A1 (zh) | 2012-09-07 |
Family
ID=44951548
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK12103749.4A HK1163087A1 (zh) | 2010-06-11 | 2012-04-17 | 得自於藤黃樹脂的經分餾的產物及其醫藥用途 |
HK12103748.5A HK1163086A1 (zh) | 2010-06-11 | 2012-04-17 | 得自於藤黃樹脂的新穎化合物及其醫藥用途 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK12103748.5A HK1163086A1 (zh) | 2010-06-11 | 2012-04-17 | 得自於藤黃樹脂的新穎化合物及其醫藥用途 |
Country Status (5)
Country | Link |
---|---|
US (4) | US9498463B2 (zh) |
EP (6) | EP2395006B1 (zh) |
JP (2) | JP5558408B2 (zh) |
HK (2) | HK1163087A1 (zh) |
TW (1) | TWI432191B (zh) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014011251A2 (en) * | 2012-03-26 | 2014-01-16 | Silcotek Corp. | Coated article and chemical vapor deposition process |
TWI432191B (zh) | 2010-06-11 | 2014-04-01 | Taiwan Sunpan Biotechnology Dev Co Ltd | 分離自藤黃樹脂的化合物以及包含有此等化合物的藥學組成物 |
CN102617590A (zh) * | 2012-03-07 | 2012-08-01 | 广州牌牌生物科技有限公司 | 一种新藤黄酸制备工艺 |
CN102603767A (zh) * | 2012-03-07 | 2012-07-25 | 广州牌牌生物科技有限公司 | 一种藤黄酸分离纯化生产工艺 |
CN103664984A (zh) * | 2013-11-28 | 2014-03-26 | 江苏康缘药业股份有限公司 | 从藤黄中提取的抗肿瘤化合物及其制备方法与用途 |
CN103664983A (zh) * | 2013-11-28 | 2014-03-26 | 江苏康缘药业股份有限公司 | 从藤黄中提取的抗肿瘤化合物及其制备方法与用途 |
CN103664979A (zh) * | 2013-11-28 | 2014-03-26 | 江苏康缘药业股份有限公司 | 从藤黄中提取的抗肿瘤化合物及其制备方法与用途 |
CN103664986B (zh) * | 2013-11-28 | 2015-11-25 | 江苏康缘药业股份有限公司 | 从藤黄中提取的抗肿瘤化合物及其制备方法与用途 |
CN105213366B (zh) * | 2014-07-03 | 2018-11-16 | 上海中医药大学 | 藤黄酮化合物的医药用途及其药物组合物 |
CN104817569B (zh) * | 2015-03-07 | 2017-11-03 | 宝鸡文理学院 | 一种同时分离藤黄中四种藤黄酸类成分的方法 |
WO2017040623A1 (en) | 2015-09-01 | 2017-03-09 | Silcotek Corp. | Thermal chemical vapor deposition coating |
CN107648217B (zh) * | 2017-09-29 | 2020-08-18 | 中国农业科学院哈尔滨兽医研究所 | 新藤黄酸或其衍生物在制备用于预防和/或治疗由细菌引起的相关疾病的药物中的用途 |
WO2020252306A1 (en) | 2019-06-14 | 2020-12-17 | Silcotek Corp. | Nano-wire growth |
CN111166738B (zh) * | 2020-01-10 | 2022-06-14 | 桂林医学院 | 毛蕊异黄酮衍生物在制备抑制内皮细胞增殖药物中的应用 |
TWI728709B (zh) * | 2020-02-19 | 2021-05-21 | 台灣森本生物科技開發股份有限公司 | 含有得自於藤黃樹脂的丙酮萃取產物的藥學組成物以及由該組成物所製得的配方 |
CN113880857B (zh) * | 2021-11-11 | 2023-03-10 | 山东大学 | 多异戊烯基取代的笼状氧杂蒽酮类化合物及其制备方法和应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6462041B1 (en) | 1999-05-21 | 2002-10-08 | Cytovia, Inc. | Gambogic acid, analogs and derivatives as activators of caspases and inducers of apoptosis |
CN1245407C (zh) | 2002-06-17 | 2006-03-15 | 杭州博大药物研究所 | 藤黄酸类化合物的复合物,其制备方法和以该复合物为活性成份的药物组合物 |
CN1235580C (zh) | 2002-08-14 | 2006-01-11 | 南京海光应用化学研究所 | 总藤黄酸制剂及其制备方法 |
CN1289505C (zh) | 2003-04-08 | 2006-12-13 | 王先荣 | 新化合物藤黄新酸的化学结构及以其为活性成份的药物制剂和用途 |
US7622497B2 (en) | 2003-12-18 | 2009-11-24 | Cytovia, Inc. | Derivatives of gambogic acid and analogs as activators of caspases and inducers of apoptosis |
CN100413868C (zh) | 2004-05-21 | 2008-08-27 | 台湾森本生物科技开发股份有限公司 | 分离自藤黄树脂并具有抑制肿瘤/癌细胞生长活性的化合物以及包含其的药物组合物 |
TWI282280B (en) | 2004-05-21 | 2007-06-11 | Taiwan Sunpan Biotechnology De | Compounds isolated from gamboge resin having activity in inhibiting the growth of tumor/cancer cells and pharmaceutical compositions comprising the same |
US7592367B2 (en) | 2005-12-23 | 2009-09-22 | Hong Kong Jockey Club Institute Of Chinese Medicine Ltd. | Compounds from Garcinia hanburyi, their use in treating cancer and method of separating epimers thereof |
CN1927861B (zh) * | 2006-07-06 | 2011-01-26 | 中国药科大学 | 一种藤黄酸衍生物及其制备方法和在制药中的应用 |
TWI432191B (zh) | 2010-06-11 | 2014-04-01 | Taiwan Sunpan Biotechnology Dev Co Ltd | 分離自藤黃樹脂的化合物以及包含有此等化合物的藥學組成物 |
-
2010
- 2010-06-11 TW TW099119107A patent/TWI432191B/zh active
-
2011
- 2011-05-06 JP JP2011103582A patent/JP5558408B2/ja active Active
- 2011-05-06 JP JP2011103554A patent/JP5441947B2/ja active Active
- 2011-05-17 US US13/068,716 patent/US9498463B2/en active Active
- 2011-05-17 US US13/068,730 patent/US20110305784A1/en not_active Abandoned
- 2011-05-24 EP EP11167253.1A patent/EP2395006B1/en active Active
- 2011-05-24 EP EP13187366.3A patent/EP2684884B1/en active Active
- 2011-05-24 EP EP13187360.6A patent/EP2684883A1/en not_active Withdrawn
- 2011-05-24 EP EP13187358.0A patent/EP2684882A1/en not_active Withdrawn
- 2011-05-24 EP EP13187370.5A patent/EP2684885A1/en not_active Withdrawn
- 2011-05-24 EP EP11167255.6A patent/EP2395007B1/en active Active
-
2012
- 2012-04-17 HK HK12103749.4A patent/HK1163087A1/zh not_active IP Right Cessation
- 2012-04-17 HK HK12103748.5A patent/HK1163086A1/zh not_active IP Right Cessation
-
2015
- 2015-12-09 US US14/964,309 patent/US20160089357A1/en not_active Abandoned
-
2016
- 2016-08-03 US US15/227,926 patent/US20160338991A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2684883A1 (en) | 2014-01-15 |
US20110305784A1 (en) | 2011-12-15 |
US20160089357A1 (en) | 2016-03-31 |
US9498463B2 (en) | 2016-11-22 |
EP2684884A1 (en) | 2014-01-15 |
US20160338991A1 (en) | 2016-11-24 |
EP2684884B1 (en) | 2016-04-27 |
JP5441947B2 (ja) | 2014-03-12 |
TW201143764A (en) | 2011-12-16 |
US20110306658A1 (en) | 2011-12-15 |
EP2395006B1 (en) | 2014-10-22 |
JP2011256162A (ja) | 2011-12-22 |
TWI432191B (zh) | 2014-04-01 |
EP2395007B1 (en) | 2014-06-25 |
JP5558408B2 (ja) | 2014-07-23 |
HK1163086A1 (zh) | 2012-09-07 |
EP2395006A1 (en) | 2011-12-14 |
JP2011256161A (ja) | 2011-12-22 |
EP2684885A1 (en) | 2014-01-15 |
EP2684882A1 (en) | 2014-01-15 |
EP2395007A1 (en) | 2011-12-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20220522 |